| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/3702 |
| Similar Terms | |
| Downloads & Tools |
198 proteins with high or low expression in Indapamide relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | 1.36 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.89 |
| HLA-F | major histocompatibility complex, class I, F | 0.88 |
| COMMD8 | COMM domain containing 8 | 0.56 |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) | 0.55 |
| CDX2 | caudal type homeobox 2 | 0.52 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) | 0.52 |
| SYN1 | synapsin I | 0.49 |
| C1ORF43 | chromosome 1 open reading frame 43 | 0.47 |
| SMTN | smoothelin | 0.46 |
| C9ORF40 | chromosome 9 open reading frame 40 | 0.45 |
| XBP1 | X-box binding protein 1 | 0.44 |
| CFAP54 | cilia and flagella associated 54 | 0.42 |
| BAG4 | BCL2-associated athanogene 4 | 0.41 |
| POLE4 | polymerase (DNA-directed), epsilon 4, accessory subunit | 0.39 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.39 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.39 |
| PFDN6 | prefoldin subunit 6 | 0.38 |
| LYST | lysosomal trafficking regulator | 0.38 |
| MED29 | mediator complex subunit 29 | 0.37 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | 0.37 |
| TIMM10 | translocase of inner mitochondrial membrane 10 homolog (yeast) | 0.36 |
| DNAH6 | dynein, axonemal, heavy chain 6 | 0.36 |
| DOCK11 | dedicator of cytokinesis 11 | 0.36 |
| USP18 | ubiquitin specific peptidase 18 | 0.34 |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 0.34 |
| DCLRE1A | DNA cross-link repair 1A | 0.33 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 0.33 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | 0.33 |
| TPM2 | tropomyosin 2 (beta) | 0.33 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.33 |
| MCTS2P | malignant T cell amplified sequence 2, pseudogene | 0.32 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.32 |
| BOLA1 | bolA family member 1 | 0.32 |
| RASSF3 | Ras association (RalGDS/AF-6) domain family member 3 | 0.31 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.31 |
| ERH | enhancer of rudimentary homolog (Drosophila) | 0.31 |
| CLASRP | CLK4-associating serine/arginine rich protein | 0.3 |
| BLOC1S4 | biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino | 0.3 |
| SHLD2 | shieldin complex subunit 2 | 0.3 |
| NABP2 | nucleic acid binding protein 2 | 0.3 |
| SUMO1 | small ubiquitin-like modifier 1 | 0.3 |
| XTBD1 | XRN2 binding domain containing 1 | 0.3 |
| ZDHHC12 | zinc finger, DHHC-type containing 12 | 0.29 |
| RPS26 | ribosomal protein S26 | 0.29 |
| MED26 | mediator complex subunit 26 | 0.29 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.28 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 0.28 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.28 |
| C12ORF73 | chromosome 12 open reading frame 73 | 0.27 |
| MED8 | mediator complex subunit 8 | 0.27 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 | 0.27 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.27 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.27 |
| CRCP | CGRP receptor component | 0.27 |
| REX1BD | required for excision 1-B domain containing | 0.27 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.26 |
| RPE | ribulose-5-phosphate-3-epimerase | 0.26 |
| TRIB3 | tribbles pseudokinase 3 | 0.26 |
| KIAA0513 | KIAA0513 | 0.26 |
| RYBP | RING1 and YY1 binding protein | 0.26 |
| OBSL1 | obscurin-like 1 | 0.26 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.26 |
| MLF1 | myeloid leukemia factor 1 | 0.26 |
| RNF17 | ring finger protein 17 | 0.25 |
| C19ORF25 | chromosome 19 open reading frame 25 | 0.25 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) | 0.25 |
| SUMO2 | small ubiquitin-like modifier 2 | 0.24 |
| ZNF669 | zinc finger protein 669 | 0.24 |
| LYSMD2 | LysM, putative peptidoglycan-binding, domain containing 2 | 0.24 |
| TMSB10 | thymosin beta 10 | 0.24 |
| PTMA | prothymosin, alpha | 0.24 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.24 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.23 |
| RNF13 | ring finger protein 13 | 0.23 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.23 |
| DPP4 | dipeptidyl-peptidase 4 | 0.23 |
| ZNRD1 | zinc ribbon domain containing 1 | 0.23 |
| AEN | apoptosis enhancing nuclease | 0.23 |
| ELOC | elongin C | 0.23 |
| NEMP2 | nuclear envelope integral membrane protein 2 | 0.23 |
| ANAPC16 | anaphase promoting complex subunit 16 | 0.23 |
| BANF1 | barrier to autointegration factor 1 | 0.23 |
| FYTTD1 | forty-two-three domain containing 1 | 0.23 |
| ACTL8 | actin-like 8 | 0.23 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit | 0.23 |
| SLC4A11 | solute carrier family 4, sodium borate transporter, member 11 | 0.23 |
| TPM3 | tropomyosin 3 | 0.23 |
| PDE9A | phosphodiesterase 9A | 0.23 |
| DCTPP1 | dCTP pyrophosphatase 1 | 0.22 |
| ARSK | arylsulfatase family, member K | 0.22 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | 0.22 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 | 0.22 |
| CFAP97 | cilia and flagella associated protein 97 | 0.22 |
| GLCCI1 | glucocorticoid induced 1 | 0.22 |
| ANKRD36C | ankyrin repeat domain 36C | 0.22 |
| RPGR | retinitis pigmentosa GTPase regulator | 0.22 |
| RNF145 | ring finger protein 145 | 0.22 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ALPK3 | alpha-kinase 3 | -2.38 |
| ESPN | espin | -1.82 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -1.04 |
| KLHL23 | kelch-like family member 23 | -0.97 |
| PIP | prolactin-induced protein | -0.96 |
| MCOLN2 | mucolipin 2 | -0.89 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.84 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) | -0.81 |
| AASDH | aminoadipate-semialdehyde dehydrogenase | -0.77 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | -0.73 |
| CCDC73 | coiled-coil domain containing 73 | -0.69 |
| ZDHHC8 | zinc finger, DHHC-type containing 8 | -0.68 |
| PHLDB3 | pleckstrin homology-like domain, family B, member 3 | -0.68 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 | -0.65 |
| VAMP8 | vesicle-associated membrane protein 8 | -0.65 |
| ZNF91 | zinc finger protein 91 | -0.62 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.57 |
| CSNK1G3 | casein kinase 1, gamma 3 | -0.55 |
| KLF2 | Kruppel-like factor 2 | -0.54 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.5 |
| ACTBL2 | actin, beta-like 2 | -0.49 |
| TICAM1 | toll-like receptor adaptor molecule 1 | -0.47 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) | -0.47 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | -0.47 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa | -0.47 |
| RASA4 | RAS p21 protein activator 4 | -0.46 |
| FAAP24 | FA core complex associated protein 24 | -0.45 |
| CCDC28A | coiled-coil domain containing 28A | -0.45 |
| PLEKHA3 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 | -0.44 |
| ZNF775 | zinc finger protein 775 | -0.44 |
| ADIRF | adipogenesis regulatory factor | -0.43 |
| DOCK3 | dedicator of cytokinesis 3 | -0.42 |
| TPPP | tubulin polymerization promoting protein | -0.42 |
| FGB | fibrinogen beta chain | -0.42 |
| SPEG | SPEG complex locus | -0.41 |
| ZNF263 | zinc finger protein 263 | -0.41 |
| FN1 | fibronectin 1 | -0.41 |
| ELOVL6 | ELOVL fatty acid elongase 6 | -0.41 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.4 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 | -0.4 |
| SRD5A3 | steroid 5 alpha-reductase 3 | -0.39 |
| HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | -0.39 |
| ZER1 | zyg-11 related, cell cycle regulator | -0.39 |
| MT1F | metallothionein 1F | -0.38 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.38 |
| HSPA8 | heat shock 70kDa protein 8 | -0.38 |
| BOK | BCL2-related ovarian killer | -0.38 |
| D2HGDH | D-2-hydroxyglutarate dehydrogenase | -0.38 |
| AKAP6 | A kinase (PRKA) anchor protein 6 | -0.37 |
| BHLHA15 | basic helix-loop-helix family, member a15 | -0.37 |
| RCOR1 | REST corepressor 1 | -0.36 |
| CCDC77 | coiled-coil domain containing 77 | -0.35 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 | -0.35 |
| MYOM3 | myomesin 3 | -0.35 |
| TRMO | tRNA methyltransferase O | -0.35 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | -0.35 |
| ITPRIPL2 | inositol 1,4,5-trisphosphate receptor interacting protein-like 2 | -0.35 |
| LAMA3 | laminin, alpha 3 | -0.35 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.34 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.34 |
| CCDC167 | coiled-coil domain containing 167 | -0.34 |
| CCDC90B | coiled-coil domain containing 90B | -0.34 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 | -0.34 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | -0.34 |
| SLC25A39 | solute carrier family 25, member 39 | -0.33 |
| INHBA | inhibin, beta A | -0.33 |
| DTD2 | D-tyrosyl-tRNA deacylase 2 (putative) | -0.33 |
| COL11A1 | collagen, type XI, alpha 1 | -0.33 |
| TTYH3 | tweety family member 3 | -0.32 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.32 |
| NOTCH3 | notch 3 | -0.32 |
| C12ORF60 | chromosome 12 open reading frame 60 | -0.32 |
| RAB30 | RAB30, member RAS oncogene family | -0.32 |
| ABTB1 | ankyrin repeat and BTB (POZ) domain containing 1 | -0.32 |
| HMCN1 | hemicentin 1 | -0.31 |
| TRIM39 | tripartite motif containing 39 | -0.31 |
| GSTM5 | glutathione S-transferase mu 5 | -0.31 |
| COL2A1 | collagen, type II, alpha 1 | -0.31 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.31 |
| PEMT | phosphatidylethanolamine N-methyltransferase | -0.31 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -0.31 |
| BMPR1B | bone morphogenetic protein receptor, type IB | -0.31 |
| NAA80 | N-alpha-acetyltransferase 80, NatH catalytic subunit | -0.31 |
| FAN1 | FANCD2/FANCI-associated nuclease 1 | -0.3 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -0.3 |
| RNF126 | ring finger protein 126 | -0.3 |
| DTNA | dystrobrevin, alpha | -0.3 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) | -0.3 |
| TMEM199 | transmembrane protein 199 | -0.29 |
| SLC35B3 | solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 | -0.29 |
| ZNF672 | zinc finger protein 672 | -0.29 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.29 |
| CAPN15 | calpain 15 | -0.29 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.29 |
| GGT1 | gamma-glutamyltransferase 1 | -0.29 |
| LANCL3 | LanC lantibiotic synthetase component C-like 3 (bacterial) | -0.29 |
| RNF111 | ring finger protein 111 | -0.28 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | -0.28 |
| PUS10 | pseudouridylate synthase 10 | -0.28 |
| ACTB | actin, beta | -0.27 |
