Indomethacin Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
External Link http://ctdbase.org/detail.go?type=chem&acc=D007213
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Genes

217 genes/proteins interacting with the chemical Indomethacin from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACE angiotensin I converting enzyme
ADCY6 adenylate cyclase 6
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C4 aldo-keto reductase family 1, member C4
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX12 arachidonate 12-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ANXA5 annexin A5
APC adenomatous polyposis coli
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP2 aquaporin 2 (collecting duct)
ATF6 activating transcription factor 6
AVP arginine vasopressin
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BDKRB1 bradykinin receptor B1
BID BH3 interacting domain death agonist
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CALCA calcitonin-related polypeptide alpha
CAPN2 calpain 2, (m/II) large subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CCNB1 cyclin B1
CCND1 cyclin D1
CCND2 cyclin D2
CCNE1 cyclin E1
CCR3 chemokine (C-C motif) receptor 3
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFLAR CASP8 and FADD-like apoptosis regulator
CGB chorionic gonadotropin, beta polypeptide
COL18A1 collagen, type XVIII, alpha 1
CRH corticotropin releasing hormone
CRYAB crystallin, alpha B
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CYCS cytochrome c, somatic
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DDIT3 DNA-damage-inducible transcript 3
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAAH fatty acid amide hydrolase
FBN1 fibrillin 1
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FGF7 fibroblast growth factor 7
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GCLC glutamate-cysteine ligase, catalytic subunit
GDF15 growth differentiation factor 15
GHRL ghrelin/obestatin prepropeptide
GLO1 glyoxalase I
GNAS GNAS complex locus
GSR glutathione reductase
GSTT1 glutathione S-transferase theta 1
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
HMOX1 heme oxygenase 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSBP1 heat shock factor binding protein 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSF1 heat shock transcription factor 1
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IL10 interleukin 10
IL11 interleukin 11
IL12A interleukin 12A
IL12B interleukin 12B
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL4 interleukin 4
IL6 interleukin 6
INS insulin
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JUN jun proto-oncogene
KEAP1 kelch-like ECH-associated protein 1
KNG1 kininogen 1
LAMC1 laminin, gamma 1 (formerly LAMB2)
LDLR low density lipoprotein receptor
LEP leptin
LTA lymphotoxin alpha
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MBP myelin basic protein
MKI67 marker of proliferation Ki-67
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEFL neurofilament, light polypeptide
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPA natriuretic peptide A
NR4A1 nuclear receptor subfamily 4, group A, member 1
NT5E 5'-nucleotidase, ecto (CD73)
PABPN1 poly(A) binding protein, nuclear 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PARP1 poly (ADP-ribose) polymerase 1
PCNA proliferating cell nuclear antigen
POMC proopiomelanocortin
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PRKCB protein kinase C, beta
PRKCE protein kinase C, epsilon
PRKCH protein kinase C, eta
PTGDR2 prostaglandin D2 receptor 2
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGR1 prostaglandin reductase 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC22A8 solute carrier family 22 (organic anion transporter), member 8
SLC22A9 solute carrier family 22 (organic anion transporter), member 9
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TAC1 tachykinin, precursor 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TJP1 tight junction protein 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TP53 tumor protein p53
TRAF2 TNF receptor-associated factor 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TXN thioredoxin
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3
UGT1A4 UDP glucuronosyltransferase 1 family, polypeptide A4
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
VEGFA vascular endothelial growth factor A
VGF VGF nerve growth factor inducible
VIM vimentin
VWF von Willebrand factor
WISP1 WNT1 inducible signaling pathway protein 1
XDH xanthine dehydrogenase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon