| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Infigratinib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Infigratinib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0831961 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0659879 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0658941 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0587073 |
| LYZ | lysozyme | 0.0511879 |
| RIGI | RNA sensor RIG-I | 0.0508627 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0497956 |
| LMO7 | LIM domain 7 | 0.0482645 |
| RNF213 | ring finger protein 213 | 0.0478711 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.047721 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0452302 |
| INTS6 | integrator complex subunit 6 | 0.0450777 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0409645 |
| ANXA2 | annexin A2 | 0.0405446 |
| NPSR1 | neuropeptide S receptor 1 | 0.0402978 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0394128 |
| AREG | amphiregulin | 0.0391763 |
| SP100 | SP100 nuclear antigen | 0.0384483 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0370396 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0370291 |
| XAF1 | XIAP associated factor 1 | 0.0363786 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0361567 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0349179 |
| EGR1 | early growth response 1 | 0.0343414 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0340584 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0334174 |
| MX2 | MX dynamin-like GTPase 2 | 0.0329197 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0325337 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0317303 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0315585 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0311109 |
| PLSCR2 | phospholipid scramblase 2 | 0.0304215 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0295236 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.028408 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.027604 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.027522 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0272192 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0268127 |
| ERBIN | erbb2 interacting protein | 0.0260946 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0257813 |
| MX1 | MX dynamin-like GTPase 1 | 0.0249116 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0244014 |
| VCL | vinculin | 0.0243175 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.0237768 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0233171 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.023174 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0224078 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.022182 |
| TMC5 | transmembrane channel-like 5 | 0.0220649 |
| TJP1 | tight junction protein 1 | 0.0218548 |
| PTGR1 | prostaglandin reductase 1 | 0.0217646 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0216294 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0216131 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0215997 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0214868 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.021187 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0206851 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0198786 |
| KYNU | kynureninase | 0.0193834 |
| ITGA6 | integrin, alpha 6 | 0.0193046 |
| PLIN2 | perilipin 2 | 0.0183251 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0182443 |
| PMP22 | peripheral myelin protein 22 | 0.0182222 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0179882 |
| MCU | mitochondrial calcium uniporter | 0.017987 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0177809 |
| SPATA13 | spermatogenesis associated 13 | 0.0177032 |
| FTL | ferritin, light polypeptide | 0.0175231 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0173698 |
| SQSTM1 | sequestosome 1 | 0.0172494 |
| PLSCR1 | phospholipid scramblase 1 | 0.0172338 |
| POF1B | premature ovarian failure, 1B | 0.0170993 |
| RASAL2 | RAS protein activator like 2 | 0.0166624 |
| MCL1 | myeloid cell leukemia 1 | 0.0166331 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0163678 |
| GK | glycerol kinase | 0.0162916 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0160568 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.015946 |
| SMAD3 | SMAD family member 3 | 0.0153259 |
| SAMD9L | sterile alpha motif domain containing 9-like | 0.0151634 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0150842 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0149388 |
| MUC20 | mucin 20, cell surface associated | 0.0149134 |
| LAMA4 | laminin, alpha 4 | 0.0149004 |
| ANKRD10 | ankyrin repeat domain 10 | 0.014828 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0146796 |
| HKDC1 | hexokinase domain containing 1 | 0.0146167 |
| FHIT | fragile histidine triad | 0.0145642 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0145525 |
| MSI2 | musashi RNA-binding protein 2 | 0.0145374 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0144994 |
| ETV6 | ets variant 6 | 0.0143328 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0141902 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0141876 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.014098 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0140952 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0140526 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0140258 |
| FBXO39 | F-box protein 39 | 0.014011 |
| NABP1 | nucleic acid binding protein 1 | 0.0139689 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.18906 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.156549 |
| UBC | ubiquitin C | -0.143686 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0719602 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0678769 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0646243 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0580303 |
| TXNIP | thioredoxin interacting protein | -0.0578966 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0533667 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0532762 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0507372 |
| AHNAK | AHNAK nucleoprotein | -0.0492213 |
| RNF43 | ring finger protein 43 | -0.0479265 |
| CALR | calreticulin | -0.0469704 |
| AHI1 | Abelson helper integration site 1 | -0.0461703 |
| CANX | calnexin | -0.0459436 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0441238 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0438496 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.043277 |
| RUNX1 | runt-related transcription factor 1 | -0.0412201 |
| RRBP1 | ribosome binding protein 1 | -0.0403389 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0396648 |
| EPCAM | epithelial cell adhesion molecule | -0.0394728 |
| B2M | beta-2-microglobulin | -0.0391145 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0388708 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0376046 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0358452 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0356584 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0340081 |
| ENO1 | enolase 1, (alpha) | -0.0339469 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0338347 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.033225 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0327653 |
| PTMA | prothymosin, alpha | -0.0314521 |
| HDLBP | high density lipoprotein binding protein | -0.030844 |
| CALU | calumenin | -0.0307071 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0306311 |
| EHF | ets homologous factor | -0.0304547 |
| NDRG1 | N-myc downstream regulated 1 | -0.0301379 |
| ACTN4 | actinin, alpha 4 | -0.0295 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.02918 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0289209 |
| IFNGR1 | interferon gamma receptor 1 | -0.028626 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0286177 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0284347 |
| STK24 | serine/threonine kinase 24 | -0.0282001 |
| OGA | O-GlcNAcase | -0.0279505 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0277952 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0276791 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0276487 |
| PKM | pyruvate kinase, muscle | -0.027614 |
| RPL23 | ribosomal protein L23 | -0.0275835 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0271234 |
| SEC24D | SEC24 family member D | -0.0270298 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0268195 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0266513 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0264316 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0263888 |
| GOLGA4 | golgin A4 | -0.02637 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0263492 |
| RAB1A | RAB1A, member RAS oncogene family | -0.026247 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0262372 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0261607 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0256596 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0254487 |
| JUN | jun proto-oncogene | -0.0253951 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0253302 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0251739 |
| PCBP2 | poly(rC) binding protein 2 | -0.0250441 |
| NCKAP5 | NCK-associated protein 5 | -0.0248497 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0247022 |
| DIAPH3 | diaphanous-related formin 3 | -0.0242093 |
| RPS6 | ribosomal protein S6 | -0.0241906 |
| COG6 | component of oligomeric golgi complex 6 | -0.0240516 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0238641 |
| RPS27A | ribosomal protein S27a | -0.0229098 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0218746 |
| GOLGB1 | golgin B1 | -0.0217635 |
| WDR26 | WD repeat domain 26 | -0.0216531 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0216444 |
| XPO1 | exportin 1 | -0.0214015 |
| SUCO | SUN domain containing ossification factor | -0.0213048 |
| PTEN | phosphatase and tensin homolog | -0.021242 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0211606 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0205745 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0205616 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0204953 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0204385 |
| PRELID2 | PRELI domain containing 2 | -0.0203967 |
| MEIS2 | Meis homeobox 2 | -0.0203266 |
| GNAS | GNAS complex locus | -0.0202495 |
| SSR1 | signal sequence receptor, alpha | -0.0201738 |
| UBL3 | ubiquitin-like 3 | -0.0200859 |
| HBS1L | HBS1-like translational GTPase | -0.0200363 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.019648 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.0196434 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0194441 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0194142 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0193265 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.0189968 |
