| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Infigratinib perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Infigratinib_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.100251 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0963524 |
| TP63 | tumor protein p63 | 0.0952771 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0733488 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0721942 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0676213 |
| CD44 | CD44 molecule (Indian blood group) | 0.0658298 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0648447 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0585169 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0581634 |
| LDHA | lactate dehydrogenase A | 0.0557312 |
| HLA-B | major histocompatibility complex, class I, B | 0.0520568 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.051565 |
| TMSB4X | thymosin beta 4, X-linked | 0.0511511 |
| APP | amyloid beta (A4) precursor protein | 0.04963 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0482623 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0482323 |
| CADM2 | cell adhesion molecule 2 | 0.0475815 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0471515 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0456622 |
| ENO1 | enolase 1, (alpha) | 0.0436638 |
| VIM | vimentin | 0.0413706 |
| CANX | calnexin | 0.0405902 |
| FMNL2 | formin-like 2 | 0.0405144 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0391642 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0390565 |
| TSC22D1 | TSC22 domain family, member 1 | 0.037156 |
| EHBP1 | EH domain binding protein 1 | 0.0362383 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0358384 |
| PDE10A | phosphodiesterase 10A | 0.0350478 |
| RUNX1 | runt-related transcription factor 1 | 0.0350161 |
| RPS12 | ribosomal protein S12 | 0.0346455 |
| SP100 | SP100 nuclear antigen | 0.0334351 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0316589 |
| RIGI | RNA sensor RIG-I | 0.0310841 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0309354 |
| AHNAK | AHNAK nucleoprotein | 0.0304171 |
| RNF213 | ring finger protein 213 | 0.0299234 |
| TNS3 | tensin 3 | 0.0297648 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0297055 |
| HDAC9 | histone deacetylase 9 | 0.0291046 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.02772 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0271806 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0270908 |
| RPS18 | ribosomal protein S18 | 0.0270662 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0270582 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0265551 |
| EPHA4 | EPH receptor A4 | 0.0262758 |
| EXOC4 | exocyst complex component 4 | 0.0259781 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0258967 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0258389 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0257941 |
| DNER | delta/notch-like EGF repeat containing | 0.0257526 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.025631 |
| CAPRIN2 | caprin family member 2 | 0.0248742 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0248444 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0242238 |
| RAD51B | RAD51 paralog B | 0.0242133 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0241093 |
| EFNA5 | ephrin-A5 | 0.0239393 |
| PGK1 | phosphoglycerate kinase 1 | 0.0238675 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0236241 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0235663 |
| PRELID2 | PRELI domain containing 2 | 0.0235554 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0235276 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0234229 |
| VCL | vinculin | 0.0230174 |
| B2M | beta-2-microglobulin | 0.0217127 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0216989 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0215216 |
| PLK2 | polo-like kinase 2 | 0.0212199 |
| MYOF | myoferlin | 0.0211987 |
| SET | SET nuclear proto-oncogene | 0.0211687 |
| SQSTM1 | sequestosome 1 | 0.021166 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0208692 |
| CALR | calreticulin | 0.0208383 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.020793 |
| PLSCR1 | phospholipid scramblase 1 | 0.0202381 |
| SDC4 | syndecan 4 | 0.0202022 |
| RPL26 | ribosomal protein L26 | 0.0200518 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0200205 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0199033 |
| RPL12 | ribosomal protein L12 | 0.0194617 |
| RPL31 | ribosomal protein L31 | 0.0190333 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0190244 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0184052 |
| AEBP2 | AE binding protein 2 | 0.0183411 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0179824 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0177215 |
| PTK2 | protein tyrosine kinase 2 | 0.0174567 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0174208 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0173728 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0172103 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.017029 |
| RPL37A | ribosomal protein L37a | 0.0168319 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0167869 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0167296 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0166777 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0166704 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0166604 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.139098 |
| MT2A | metallothionein 2A | -0.0792691 |
| MT1X | metallothionein 1X | -0.0388498 |
| TMSB10 | thymosin beta 10 | -0.0375188 |
| RTN4 | reticulon 4 | -0.026082 |
| TXNRD1 | thioredoxin reductase 1 | -0.0259689 |
| ACTG1 | actin gamma 1 | -0.0254212 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0245412 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0227798 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0217766 |
| FOSL1 | FOS-like antigen 1 | -0.0208057 |
| RBM25 | RNA binding motif protein 25 | -0.020387 |
| POTEF | POTE ankyrin domain family, member F | -0.019581 |
| HMGA1 | high mobility group AT-hook 1 | -0.019308 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0189524 |
| FTL | ferritin, light polypeptide | -0.0185957 |
| TMEM41B | transmembrane protein 41B | -0.0181395 |
| SRGN | serglycin | -0.0177671 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0152454 |
| EGR1 | early growth response 1 | -0.0150719 |
| UPP1 | uridine phosphorylase 1 | -0.0139961 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0139605 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0127522 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0126156 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0124649 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0122978 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.011618 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0115334 |
| S100A10 | S100 calcium binding protein A10 | -0.0114353 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0114329 |
| RPL5 | ribosomal protein L5 | -0.0114243 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0111348 |
| AREG | amphiregulin | -0.0110552 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0104931 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.01037 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0102988 |
| RAI1 | retinoic acid induced 1 | -0.0101979 |
| EMP1 | epithelial membrane protein 1 | -0.00998211 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.00984733 |
| ANGPTL4 | angiopoietin-like 4 | -0.00968327 |
| YBX3 | Y box binding protein 3 | -0.00941899 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0093252 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0092275 |
| PRRC2C | proline-rich coiled-coil 2C | -0.00916915 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.00909732 |
| CENPF | centromere protein F, 350/400kDa | -0.00900868 |
| RPS6 | ribosomal protein S6 | -0.00878773 |
| DPP9 | dipeptidyl-peptidase 9 | -0.00863503 |
| RPS15 | ribosomal protein S15 | -0.00861414 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.00842227 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0082708 |
| RPL23 | ribosomal protein L23 | -0.00817536 |
| MKI67 | marker of proliferation Ki-67 | -0.00815839 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00808982 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.00806498 |
| UBXN4 | UBX domain protein 4 | -0.00805121 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.00798806 |
| RBM27 | RNA binding motif protein 27 | -0.00791121 |
| RPL32 | ribosomal protein L32 | -0.00790117 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.00782743 |
| PRDX1 | peroxiredoxin 1 | -0.00774088 |
| WDR45B | WD repeat domain 45B | -0.00769933 |
| MT1E | metallothionein 1E | -0.00758444 |
| CCNL1 | cyclin L1 | -0.00751015 |
| PFN1 | profilin 1 | -0.00738524 |
| KIF14 | kinesin family member 14 | -0.00731873 |
| SGO2 | shugoshin 2 | -0.00708966 |
| KIF18B | kinesin family member 18B | -0.00702751 |
| LHX1 | LIM homeobox 1 | -0.00696844 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00696344 |
| POM121C | POM121 transmembrane nucleoporin C | -0.00696115 |
| WASF2 | WAS protein family, member 2 | -0.00693356 |
| BRD4 | bromodomain containing 4 | -0.00683539 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.00681473 |
| ATN1 | atrophin 1 | -0.00675937 |
| SMC4 | structural maintenance of chromosomes 4 | -0.00672702 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00671681 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.006676 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.00652483 |
| RPS21 | ribosomal protein S21 | -0.00651923 |
| TAPBP | TAP binding protein (tapasin) | -0.00650123 |
| MYADM | myeloid-associated differentiation marker | -0.00648245 |
| CDCP1 | CUB domain containing protein 1 | -0.00647348 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.00645694 |
| ATF4 | activating transcription factor 4 | -0.0063932 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | -0.00630257 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.00628481 |
| CDCA2 | cell division cycle associated 2 | -0.00620484 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.00611518 |
| TSC22D2 | TSC22 domain family, member 2 | -0.00607757 |
| SNX14 | sorting nexin 14 | -0.00605423 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) | -0.00604432 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.00601381 |
| CENPE | centromere protein E, 312kDa | -0.00591814 |
| EVI5 | ecotropic viral integration site 5 | -0.00591146 |
| RPL8 | ribosomal protein L8 | -0.00589798 |
| MYL12B | myosin, light chain 12B, regulatory | -0.00587405 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00583497 |
| KRT19 | keratin 19, type I | -0.00582411 |
| GOLT1A | golgi transport 1A | -0.00577785 |
