| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Infigratinib perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Infigratinib_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.201515 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.180057 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.133206 |
| ASPH | aspartate beta-hydroxylase | 0.128682 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.110445 |
| ENO1 | enolase 1, (alpha) | 0.0907116 |
| EFNA5 | ephrin-A5 | 0.083507 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0795373 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.077057 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0736323 |
| ATXN1 | ataxin 1 | 0.0701957 |
| FN1 | fibronectin 1 | 0.0690591 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0677505 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0646113 |
| PGK1 | phosphoglycerate kinase 1 | 0.0639457 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0598535 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.05961 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0589625 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.055785 |
| SLTM | SAFB-like, transcription modulator | 0.0547975 |
| S100A9 | S100 calcium binding protein A9 | 0.0542339 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.054096 |
| LDHA | lactate dehydrogenase A | 0.0533388 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0529774 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0524229 |
| PCBP2 | poly(rC) binding protein 2 | 0.0494292 |
| PRKCA | protein kinase C, alpha | 0.0493785 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.048605 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0484706 |
| RPL35A | ribosomal protein L35a | 0.0474273 |
| RBM39 | RNA binding motif protein 39 | 0.047093 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0465281 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0451468 |
| FLNB | filamin B, beta | 0.0443891 |
| TMSB10 | thymosin beta 10 | 0.0434237 |
| PTMA | prothymosin, alpha | 0.0433888 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0424929 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0422419 |
| MATR3 | matrin 3 | 0.0410029 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0402756 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0390336 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0384203 |
| TOP1 | topoisomerase (DNA) I | 0.038348 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0383221 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0381091 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0379349 |
| RPS8 | ribosomal protein S8 | 0.0379081 |
| NF1 | neurofibromin 1 | 0.0378715 |
| EGR1 | early growth response 1 | 0.0377889 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0375816 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0375796 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0375716 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0370585 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0367321 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0366971 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0358744 |
| OGA | O-GlcNAcase | 0.0358596 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0358579 |
| SIK3 | SIK family kinase 3 | 0.0357341 |
| RPS12 | ribosomal protein S12 | 0.0354558 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0352608 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.035134 |
| CADM2 | cell adhesion molecule 2 | 0.0348873 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0344909 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0338249 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0336163 |
| JMJD1C | jumonji domain containing 1C | 0.0335786 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0334962 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0333643 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0333483 |
| GNAS | GNAS complex locus | 0.0332089 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0328929 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0327823 |
| CANX | calnexin | 0.0326028 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0325538 |
| MED13L | mediator complex subunit 13-like | 0.0323098 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0322577 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0322114 |
| S100A10 | S100 calcium binding protein A10 | 0.0321833 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0320913 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0315526 |
| RIGI | RNA sensor RIG-I | 0.0315283 |
| NDRG1 | N-myc downstream regulated 1 | 0.031183 |
| EXOC4 | exocyst complex component 4 | 0.0309519 |
| TES | testin LIM domain protein | 0.0307443 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0305287 |
| FRMD5 | FERM domain containing 5 | 0.0304361 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0300621 |
| RPL12 | ribosomal protein L12 | 0.0297091 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0291753 |
| DTNA | dystrobrevin, alpha | 0.0291447 |
| KYNU | kynureninase | 0.028672 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0286703 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0286549 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0285566 |
| CDH13 | cadherin 13 | 0.028552 |
| RPS14 | ribosomal protein S14 | 0.0285368 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0284918 |
| THBS1 | thrombospondin 1 | 0.0283718 |
| USP34 | ubiquitin specific peptidase 34 | 0.0281802 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.172542 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.142293 |
| MYO1E | myosin IE | -0.0958183 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0838295 |
| SVIL | supervillin | -0.0824991 |
| LAMB3 | laminin, beta 3 | -0.081275 |
| LAMC2 | laminin, gamma 2 | -0.0712368 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0708491 |
| ATOSA | atos homolog A | -0.0689449 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0678152 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0644666 |
| MUC16 | mucin 16, cell surface associated | -0.0626954 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0617941 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0589289 |
| CMIP | c-Maf inducing protein | -0.057915 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0577609 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0538603 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0532006 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0508386 |
| TC2N | tandem C2 domains, nuclear | -0.0488455 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0486064 |
| WASL | Wiskott-Aldrich syndrome-like | -0.047971 |
| SDCBP2 | syndecan binding protein (syntenin) 2 | -0.0479701 |
| GLUL | glutamate-ammonia ligase | -0.0466346 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.046375 |
| OCLN | occludin | -0.0453948 |
| MYO6 | myosin VI | -0.0451628 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0446356 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0445283 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.0427829 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0424285 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0422424 |
| SGMS2 | sphingomyelin synthase 2 | -0.0419897 |
| TAOK3 | TAO kinase 3 | -0.0418776 |
| RBM47 | RNA binding motif protein 47 | -0.041383 |
| TJP2 | tight junction protein 2 | -0.0407001 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0395691 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.039014 |
| JUP | junction plakoglobin | -0.0387493 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0386455 |
| DENND2C | DENN/MADD domain containing 2C | -0.038436 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0383009 |
| ANXA2 | annexin A2 | -0.0372003 |
| FOXO1 | forkhead box O1 | -0.0369974 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0368034 |
| IRF6 | interferon regulatory factor 6 | -0.0362316 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0361108 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0360865 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0357132 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.035664 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0356094 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0355184 |
| OXR1 | oxidation resistance 1 | -0.0354226 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0353568 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 | -0.0352018 |
| APTX | aprataxin | -0.0346243 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.034608 |
| ZNF217 | zinc finger protein 217 | -0.0345901 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0343647 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0341014 |
| PALLD | palladin, cytoskeletal associated protein | -0.0340621 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0337569 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0337102 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0336564 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0335864 |
| AHNAK | AHNAK nucleoprotein | -0.0335186 |
| TMEM165 | transmembrane protein 165 | -0.0335163 |
| STEAP4 | STEAP family member 4 | -0.0333461 |
| RUNX1 | runt-related transcription factor 1 | -0.0330075 |
| RESF1 | retroelement silencing factor 1 | -0.0329749 |
| NEBL | nebulette | -0.0328937 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0328915 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0327965 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0325992 |
| FRMD6 | FERM domain containing 6 | -0.0325971 |
| MXD1 | MAX dimerization protein 1 | -0.0324766 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0323798 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0323223 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0323062 |
| FBXO34 | F-box protein 34 | -0.0321233 |
| GOLGA4 | golgin A4 | -0.0319059 |
| GLG1 | golgi glycoprotein 1 | -0.0316384 |
| TPCN1 | two pore segment channel 1 | -0.0316132 |
| ATP11A | ATPase, class VI, type 11A | -0.0315217 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0309194 |
| SPPL3 | signal peptide peptidase like 3 | -0.0307822 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.0307358 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0304302 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0303739 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0303693 |
| CD44 | CD44 molecule (Indian blood group) | -0.0296933 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0293903 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.029337 |
| GLCCI1 | glucocorticoid induced 1 | -0.0292913 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0291474 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0290906 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0289768 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0287446 |
| OXSR1 | oxidative stress responsive 1 | -0.0285747 |
| HOOK3 | hook microtubule-tethering protein 3 | -0.0285702 |
