| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Infigratinib perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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186 genes differentially expressed following the Infigratinib_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0691078 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0650878 |
| MT2A | metallothionein 2A | 0.0642686 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0620179 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0618099 |
| EGR1 | early growth response 1 | 0.0548192 |
| RUNX1 | runt-related transcription factor 1 | 0.0547673 |
| PTMA | prothymosin, alpha | 0.0534363 |
| SQSTM1 | sequestosome 1 | 0.0531332 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0519203 |
| PGK1 | phosphoglycerate kinase 1 | 0.0512931 |
| RPL23 | ribosomal protein L23 | 0.0504634 |
| RPL31 | ribosomal protein L31 | 0.050176 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0488555 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0426964 |
| APP | amyloid beta (A4) precursor protein | 0.0419356 |
| LMO7 | LIM domain 7 | 0.0416307 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0395904 |
| B2M | beta-2-microglobulin | 0.0385944 |
| IGF2 | insulin-like growth factor 2 | 0.038496 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0381205 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0377991 |
| ENO1 | enolase 1, (alpha) | 0.0376278 |
| LDHA | lactate dehydrogenase A | 0.0374791 |
| TNS3 | tensin 3 | 0.037062 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.036734 |
| PTK2 | protein tyrosine kinase 2 | 0.0365604 |
| GPC6 | glypican 6 | 0.0364599 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.035871 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0351412 |
| MED13 | mediator complex subunit 13 | 0.0332244 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0323303 |
| CANX | calnexin | 0.0299206 |
| NAV2 | neuron navigator 2 | 0.0282668 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0281248 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0280959 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.027642 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0276004 |
| JMJD1C | jumonji domain containing 1C | 0.025657 |
| EZR | ezrin | 0.0252836 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0247824 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0245457 |
| HMGA2 | high mobility group AT-hook 2 | 0.0242794 |
| DSPP | dentin sialophosphoprotein | 0.0232921 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0230762 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0230181 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0224861 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0221868 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.021767 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0217176 |
| RPS3 | ribosomal protein S3 | 0.0215745 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.021573 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0207378 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0202196 |
| CEP350 | centrosomal protein 350kDa | 0.0200191 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.019685 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0196219 |
| FTL | ferritin, light polypeptide | 0.0195853 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0189688 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | 0.0189654 |
| ASPH | aspartate beta-hydroxylase | 0.0188395 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0187679 |
| PKM | pyruvate kinase, muscle | 0.0182957 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0182589 |
| RPL37A | ribosomal protein L37a | 0.018084 |
| SEPTIN9 | septin 9 | 0.0179659 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0179501 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0176661 |
| RPS21 | ribosomal protein S21 | 0.0172207 |
| TRIM26 | tripartite motif containing 26 | 0.0165285 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0159966 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0153586 |
| RPS12 | ribosomal protein S12 | 0.0151705 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0149467 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0147548 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0146765 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0138653 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0130538 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0127671 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0127381 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0126905 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0123748 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.011879 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0112742 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0109968 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00982745 |
| MCL1 | myeloid cell leukemia 1 | 0.00973325 |
| RPS6 | ribosomal protein S6 | 0.00969751 |
| GOLGA4 | golgin A4 | 0.00959476 |
| CCNI | cyclin I | 0.00953141 |
| RPS27A | ribosomal protein S27a | 0.00917447 |
| ATXN1 | ataxin 1 | 0.00914747 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.00853565 |
| DST | dystonin | 0.00849465 |
| ACTG1 | actin gamma 1 | 0.00792824 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.00725547 |
| FN1 | fibronectin 1 | 0.0071831 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.00716715 |
| TPM4 | tropomyosin 4 | 0.00674126 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.00654736 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0963927 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0959344 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0924645 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0905345 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0900401 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.086838 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0667759 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0626929 |
| TMSB10 | thymosin beta 10 | -0.0609641 |
| INHBA | inhibin, beta A | -0.0589363 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0567475 |
| MYOF | myoferlin | -0.0499753 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0454301 |
| VIM | vimentin | -0.0444185 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0439257 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.041654 |
| EFNA5 | ephrin-A5 | -0.0406525 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0402791 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0398424 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0396946 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0393231 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0368765 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0368324 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0338645 |
| CDH13 | cadherin 13 | -0.0289914 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0276655 |
| EGFR | epidermal growth factor receptor | -0.02748 |
| DOCK5 | dedicator of cytokinesis 5 | -0.027274 |
| GPHN | gephyrin | -0.0270433 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0266419 |
| TMEM165 | transmembrane protein 165 | -0.0263788 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0245945 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0243107 |
| CD44 | CD44 molecule (Indian blood group) | -0.0234055 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.023329 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0232853 |
| CAVIN1 | caveolae associated protein 1 | -0.0229228 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0225206 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0212015 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0206216 |
| CUX1 | cut-like homeobox 1 | -0.0202848 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0200099 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0194044 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0193885 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0192654 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0187125 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0180293 |
| MED13L | mediator complex subunit 13-like | -0.0176939 |
| SPAG9 | sperm associated antigen 9 | -0.0173455 |
| ZNF609 | zinc finger protein 609 | -0.0172941 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0170957 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0163155 |
| TXNRD1 | thioredoxin reductase 1 | -0.0156613 |
| MYO10 | myosin X | -0.0156484 |
| OXR1 | oxidation resistance 1 | -0.0153456 |
| USP34 | ubiquitin specific peptidase 34 | -0.0148632 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.014618 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0145121 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0142519 |
| GLG1 | golgi glycoprotein 1 | -0.0141897 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0138629 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0135487 |
| DOCK4 | dedicator of cytokinesis 4 | -0.013136 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0131112 |
| GLIS3 | GLIS family zinc finger 3 | -0.0129792 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0119841 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0109514 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0106887 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0106581 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0106471 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0103071 |
| OGA | O-GlcNAcase | -0.0102102 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.00843944 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.00732209 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.00694325 |
| RPL35A | ribosomal protein L35a | -0.00652965 |
| AHNAK | AHNAK nucleoprotein | -0.00587054 |
| PDE10A | phosphodiesterase 10A | -0.00311353 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00264668 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.00239908 |
| RPL26 | ribosomal protein L26 | -0.00218493 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.00185418 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.00138919 |
| BPTF | bromodomain PHD finger transcription factor | -0.00134035 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.00109739 |
| FAM13A | family with sequence similarity 13, member A | -6.24906E-4 |
