| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Infigratinib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Infigratinib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.111931 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.103432 |
| PKM | pyruvate kinase, muscle | 0.0987412 |
| FOXP1 | forkhead box P1 | 0.0799702 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0748481 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0730309 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0720782 |
| TJP1 | tight junction protein 1 | 0.0700542 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0681873 |
| PTMA | prothymosin, alpha | 0.0678358 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0660152 |
| VCL | vinculin | 0.0648269 |
| TMSB4X | thymosin beta 4, X-linked | 0.0632136 |
| HDAC9 | histone deacetylase 9 | 0.0582141 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.057975 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0562457 |
| EGFR | epidermal growth factor receptor | 0.054346 |
| LDHA | lactate dehydrogenase A | 0.0538291 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0530592 |
| ENO1 | enolase 1, (alpha) | 0.050067 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0480557 |
| EZR | ezrin | 0.0472848 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0461867 |
| GOLGA4 | golgin A4 | 0.0406777 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.040643 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0401971 |
| PGK1 | phosphoglycerate kinase 1 | 0.0396477 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0388318 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0382328 |
| S100A6 | S100 calcium binding protein A6 | 0.037128 |
| SMYD3 | SET and MYND domain containing 3 | 0.0362197 |
| LOC112694756 | uncharaterized LOC112694756 | 0.035419 |
| NBEA | neurobeachin | 0.0313147 |
| RTN4 | reticulon 4 | 0.0310368 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0306282 |
| ZNF292 | zinc finger protein 292 | 0.0296906 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0292698 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0283797 |
| B2M | beta-2-microglobulin | 0.028025 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0275935 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0271839 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0271069 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0268684 |
| CALR | calreticulin | 0.0257154 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0250762 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0247268 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0242228 |
| HDLBP | high density lipoprotein binding protein | 0.0239592 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0225769 |
| DSTN | destrin (actin depolymerizing factor) | 0.0225418 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0221502 |
| PCBP2 | poly(rC) binding protein 2 | 0.0221293 |
| POTEF | POTE ankyrin domain family, member F | 0.0219011 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0218456 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0217819 |
| AHNAK | AHNAK nucleoprotein | 0.0217086 |
| RBM39 | RNA binding motif protein 39 | 0.0216545 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0215516 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0214653 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0212561 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0211864 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0211671 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0211309 |
| NUP58 | nucleoporin 58 | 0.0211176 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0211129 |
| NBAS | neuroblastoma amplified sequence | 0.0210218 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0210178 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0209139 |
| DUSP4 | dual specificity phosphatase 4 | 0.0208674 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0207453 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.020725 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.020724 |
| ANK2 | ankyrin 2, neuronal | 0.020507 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0204671 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0204283 |
| PARD3 | par-3 family cell polarity regulator | 0.0204113 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0203847 |
| MLIP | muscular LMNA-interacting protein | 0.0202626 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0200502 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0200391 |
| NFIA | nuclear factor I/A | 0.0198987 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0198324 |
| ECT2 | epithelial cell transforming 2 | 0.019717 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0197134 |
| EXOC6B | exocyst complex component 6B | 0.0194184 |
| PFN1 | profilin 1 | 0.0194143 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0193463 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0192712 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0192287 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0192257 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0191372 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0191216 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0190522 |
| SQSTM1 | sequestosome 1 | 0.0190519 |
| RNF145 | ring finger protein 145 | 0.0189545 |
| USP34 | ubiquitin specific peptidase 34 | 0.0188612 |
| TCF12 | transcription factor 12 | 0.0187945 |
| TXNRD1 | thioredoxin reductase 1 | 0.0187916 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0186932 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0185898 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.107386 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.022695 |
| BMP10 | bone morphogenetic protein 10 | -0.0173802 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.014519 |
| NAV2 | neuron navigator 2 | -0.0127816 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0127307 |
| MKI67 | marker of proliferation Ki-67 | -0.0124637 |
| DIAPH3 | diaphanous-related formin 3 | -0.0104673 |
| CACYBP | calcyclin binding protein | -0.0102197 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.00998824 |
| PDE10A | phosphodiesterase 10A | -0.00947534 |
| FN1 | fibronectin 1 | -0.00922782 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.00909908 |
| CENPE | centromere protein E, 312kDa | -0.00857259 |
| HSPE1 | heat shock 10kDa protein 1 | -0.00851562 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0084287 |
| HMGA2 | high mobility group AT-hook 2 | -0.00836144 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.00834898 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.00771488 |
| FHIT | fragile histidine triad | -0.00756579 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00705408 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0070458 |
| NAV1 | neuron navigator 1 | -0.00701076 |
| UBB | ubiquitin B | -0.00696005 |
| GLIS3 | GLIS family zinc finger 3 | -0.00688026 |
| GSE1 | Gse1 coiled-coil protein | -0.00687638 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -0.0067235 |
| IGF2 | insulin-like growth factor 2 | -0.00670698 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00667127 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00655816 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00641038 |
| H1-4 | H1.4 linker histone, cluster member | -0.00637286 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.00608127 |
| RPL34 | ribosomal protein L34 | -0.00602694 |
| SCG5 | secretogranin V | -0.00600826 |
| HSPA8 | heat shock 70kDa protein 8 | -0.00599348 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00592752 |
| FRMD4A | FERM domain containing 4A | -0.00592619 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.00589533 |
| RRM2 | ribonucleotide reductase M2 | -0.00583179 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.00573497 |
| CWF19L2 | CWF19-like 2, cell cycle control (S. pombe) | -0.00567024 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.00556024 |
| SACK1D | scaffolding CK1 anchoring protein D | -0.0055544 |
| CD44 | CD44 molecule (Indian blood group) | -0.00552621 |
| CFAP251 | cilia and flagella associated protein 251 | -0.00552428 |
| MTFR1 | mitochondrial fission regulator 1 | -0.00550061 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.00549729 |
| IRS1 | insulin receptor substrate 1 | -0.00548406 |
| RCC1 | regulator of chromosome condensation 1 | -0.00546981 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00539086 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00535093 |
| BAG3 | BCL2-associated athanogene 3 | -0.00534898 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.00525247 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.00516356 |
| KNTC1 | kinetochore associated 1 | -0.00516184 |
| EMP1 | epithelial membrane protein 1 | -0.00506773 |
| HJURP | Holliday junction recognition protein | -0.00506758 |
| SAPCD2 | suppressor APC domain containing 2 | -0.00506335 |
| FANCA | Fanconi anemia, complementation group A | -0.00504968 |
| RPL28 | ribosomal protein L28 | -0.00504664 |
| KLHL12 | kelch-like family member 12 | -0.0050228 |
| CSNK1G2 | casein kinase 1, gamma 2 | -0.0049935 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.00495187 |
| KIF18B | kinesin family member 18B | -0.00495187 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.00487468 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00485151 |
| VIM | vimentin | -0.00484242 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | -0.00476903 |
| EDF1 | endothelial differentiation-related factor 1 | -0.00473958 |
| STIL | SCL/TAL1 interrupting locus | -0.00470054 |
| TMPO | thymopoietin | -0.00468608 |
| ABHD3 | abhydrolase domain containing 3 | -0.00466453 |
| KNL1 | kinetochore scaffold 1 | -0.00463655 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.00463607 |
| SUGP2 | SURP and G patch domain containing 2 | -0.00461836 |
| MYH15 | myosin, heavy chain 15 | -0.00461047 |
| AUTS2 | autism susceptibility candidate 2 | -0.00456751 |
| DST | dystonin | -0.00455627 |
| ZNF432 | zinc finger protein 432 | -0.00453677 |
| APLF | aprataxin and PNKP like factor | -0.00453042 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0045036 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.00449592 |
| OXTR | oxytocin receptor | -0.00448338 |
| RPL27 | ribosomal protein L27 | -0.00447392 |
| ZNF780B | zinc finger protein 780B | -0.00447105 |
| TRAF3 | TNF receptor-associated factor 3 | -0.00444579 |
| ZNF675 | zinc finger protein 675 | -0.00439413 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.00437896 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.00435327 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.00430037 |
| FANCD2 | Fanconi anemia, complementation group D2 | -0.00429361 |
| TNRC6C | trinucleotide repeat containing 6C | -0.00428748 |
| MYOF | myoferlin | -0.00428174 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | -0.00428109 |
| RPL37 | ribosomal protein L37 | -0.0042566 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00423719 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.00423424 |
| STIP1 | stress-induced phosphoprotein 1 | -0.00423247 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.00420861 |
