| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Infigratinib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Infigratinib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHA | lactate dehydrogenase A | 0.185365 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.170006 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.123926 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0853812 |
| VEGFA | vascular endothelial growth factor A | 0.0825007 |
| HLA-B | major histocompatibility complex, class I, B | 0.0807222 |
| ENO1 | enolase 1, (alpha) | 0.0771395 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0739274 |
| NDRG1 | N-myc downstream regulated 1 | 0.0729196 |
| PCBP2 | poly(rC) binding protein 2 | 0.0646393 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0638915 |
| B2M | beta-2-microglobulin | 0.0634893 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0630322 |
| PKM | pyruvate kinase, muscle | 0.0624476 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0615453 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0615098 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0610793 |
| VIM | vimentin | 0.0597088 |
| ZNF292 | zinc finger protein 292 | 0.0583916 |
| SFTPA2 | surfactant protein A2 | 0.0569344 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0561011 |
| PGK1 | phosphoglycerate kinase 1 | 0.0559358 |
| FN1 | fibronectin 1 | 0.054146 |
| CALR | calreticulin | 0.053621 |
| TXNIP | thioredoxin interacting protein | 0.052541 |
| PDE10A | phosphodiesterase 10A | 0.0521231 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0515719 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0499076 |
| GOLGA4 | golgin A4 | 0.0497949 |
| ARRDC3 | arrestin domain containing 3 | 0.0483878 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0478287 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0462915 |
| HELZ | helicase with zinc finger | 0.0413778 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0409669 |
| MYOF | myoferlin | 0.0396673 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0389549 |
| OGA | O-GlcNAcase | 0.0389339 |
| HLA-A | major histocompatibility complex, class I, A | 0.0378224 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0369835 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0366943 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0360613 |
| YBX1 | Y box binding protein 1 | 0.0355257 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0343404 |
| RPS4X | ribosomal protein S4, X-linked | 0.0336809 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0330696 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.031727 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0314633 |
| FLNB | filamin B, beta | 0.0309509 |
| MSN | moesin | 0.0303636 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0302458 |
| MATR3 | matrin 3 | 0.0301969 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0298114 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0293542 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0291667 |
| TMSB10 | thymosin beta 10 | 0.0291026 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0290503 |
| ANXA2 | annexin A2 | 0.0288363 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0287963 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0287024 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0286595 |
| ATP13A3 | ATPase type 13A3 | 0.0286096 |
| CCNL1 | cyclin L1 | 0.028452 |
| PTMA | prothymosin, alpha | 0.0281411 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0277553 |
| CDK19 | cyclin-dependent kinase 19 | 0.0275783 |
| MXI1 | MAX interactor 1, dimerization protein | 0.027443 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0273373 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0269025 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0266121 |
| CANX | calnexin | 0.0263573 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0261246 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0260769 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.025822 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0257578 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0256456 |
| USP37 | ubiquitin specific peptidase 37 | 0.0245914 |
| RBM39 | RNA binding motif protein 39 | 0.0241982 |
| SPAG9 | sperm associated antigen 9 | 0.0241418 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0240364 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0239755 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0238983 |
| FLNA | filamin A, alpha | 0.0238784 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0235478 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0235348 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0233438 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0232097 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0228377 |
| PRELID2 | PRELI domain containing 2 | 0.022796 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0227277 |
| OPTN | optineurin | 0.0226659 |
| WAC | WW domain containing adaptor with coiled-coil | 0.02246 |
| BRD2 | bromodomain containing 2 | 0.0223994 |
| EGR1 | early growth response 1 | 0.0223303 |
| S100A9 | S100 calcium binding protein A9 | 0.0218983 |
| POTEF | POTE ankyrin domain family, member F | 0.0217341 |
| TAGLN2 | transgelin 2 | 0.0217191 |
| SEPTIN7 | septin 7 | 0.0216301 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0215445 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0214601 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0212963 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.215784 |
| GLIS3 | GLIS family zinc finger 3 | -0.108762 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0999686 |
| FRMD4A | FERM domain containing 4A | -0.0956837 |
| HMGA2 | high mobility group AT-hook 2 | -0.0832475 |
| VCL | vinculin | -0.0719193 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0674206 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0623916 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0616792 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0611826 |
| NABP1 | nucleic acid binding protein 1 | -0.0536543 |
| IER3 | immediate early response 3 | -0.0528522 |
| HSPA1A | heat shock 70kDa protein 1A | -0.052784 |
| BICC1 | BicC family RNA binding protein 1 | -0.0501116 |
| CDH13 | cadherin 13 | -0.0475264 |
| TMEM132D | transmembrane protein 132D | -0.0449343 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0438315 |
| INHBA | inhibin, beta A | -0.0429909 |
| RAI14 | retinoic acid induced 14 | -0.0429043 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0425416 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0417163 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0412366 |
| DIAPH2 | diaphanous-related formin 2 | -0.0399367 |
| INTS6 | integrator complex subunit 6 | -0.0396601 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0390065 |
| KYNU | kynureninase | -0.0388816 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0377736 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0368089 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0358934 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0352027 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0348346 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.034104 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0339399 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0336334 |
| CD44 | CD44 molecule (Indian blood group) | -0.0327893 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0303784 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0298449 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0293322 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0291295 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0291158 |
| PALLD | palladin, cytoskeletal associated protein | -0.0283656 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0271829 |
| HDAC9 | histone deacetylase 9 | -0.0262978 |
| EGFR | epidermal growth factor receptor | -0.0261401 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0257878 |
| TLE4 | transducin-like enhancer of split 4 | -0.0248715 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0246224 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0242446 |
| HSPA8 | heat shock 70kDa protein 8 | -0.024121 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0235393 |
| EFNA5 | ephrin-A5 | -0.0235266 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0231773 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0231004 |
| CLIC4 | chloride intracellular channel 4 | -0.0229602 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0227948 |
| MT2A | metallothionein 2A | -0.0227924 |
| GPC6 | glypican 6 | -0.0226892 |
| HMOX1 | heme oxygenase 1 | -0.0224661 |
| TNS3 | tensin 3 | -0.0223589 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0223265 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0220799 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0216739 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0215985 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0214514 |
| FBXO11 | F-box protein 11 | -0.0214165 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0212967 |
| OSMR | oncostatin M receptor | -0.0211815 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0210264 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0208974 |
| TNNC1 | troponin C type 1 (slow) | -0.0205075 |
| PHF3 | PHD finger protein 3 | -0.0205042 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.020362 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0199866 |
| GDF15 | growth differentiation factor 15 | -0.019917 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.019886 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0198468 |
| KLHL5 | kelch-like family member 5 | -0.019773 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0197591 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0188739 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0186729 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0186131 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.018475 |
| WFDC10B | WAP four-disulfide core domain 10B | -0.0182633 |
| ATG7 | autophagy related 7 | -0.0179601 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0178194 |
| NRP1 | neuropilin 1 | -0.0177904 |
| RNF213 | ring finger protein 213 | -0.0177414 |
| IL6 | interleukin 6 | -0.0175993 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0175939 |
| DNER | delta/notch-like EGF repeat containing | -0.0175729 |
| CEP112 | centrosomal protein 112kDa | -0.0175607 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0175539 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0174229 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0172292 |
| STK17A | serine/threonine kinase 17a | -0.0171118 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0169956 |
| RPL37A | ribosomal protein L37a | -0.0168777 |
| CDK12 | cyclin-dependent kinase 12 | -0.01662 |
| ZNF217 | zinc finger protein 217 | -0.0165606 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0165299 |
