| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Infigratinib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Infigratinib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.152693 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.101983 |
| LDHA | lactate dehydrogenase A | 0.0839009 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0706788 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.066618 |
| ENO1 | enolase 1, (alpha) | 0.0641098 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0586857 |
| FN1 | fibronectin 1 | 0.0542323 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0516677 |
| COL5A1 | collagen, type V, alpha 1 | 0.0497794 |
| PRELID2 | PRELI domain containing 2 | 0.0475436 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0473671 |
| VCL | vinculin | 0.0469371 |
| CANX | calnexin | 0.0467708 |
| AHNAK | AHNAK nucleoprotein | 0.0445196 |
| CALR | calreticulin | 0.0440002 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0438858 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0427965 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0410987 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.040451 |
| CALD1 | caldesmon 1 | 0.0389767 |
| PKM | pyruvate kinase, muscle | 0.0358436 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0348151 |
| PGK1 | phosphoglycerate kinase 1 | 0.0339026 |
| ATXN1 | ataxin 1 | 0.0336918 |
| PRSS23 | protease, serine, 23 | 0.0329038 |
| KYNU | kynureninase | 0.0324013 |
| LOXL2 | lysyl oxidase-like 2 | 0.0310098 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0303652 |
| RUNX1 | runt-related transcription factor 1 | 0.0300756 |
| ASPH | aspartate beta-hydroxylase | 0.0290273 |
| B2M | beta-2-microglobulin | 0.0289297 |
| COL1A2 | collagen, type I, alpha 2 | 0.0279302 |
| CDH13 | cadherin 13 | 0.0277629 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0276505 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0269607 |
| CD44 | CD44 molecule (Indian blood group) | 0.0261969 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0260455 |
| POTEF | POTE ankyrin domain family, member F | 0.0260079 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0259806 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0257688 |
| NRXN3 | neurexin 3 | 0.0256732 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0255082 |
| THBS1 | thrombospondin 1 | 0.0254894 |
| VIM | vimentin | 0.025095 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0249093 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0246522 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0246336 |
| TPM4 | tropomyosin 4 | 0.0246094 |
| CALU | calumenin | 0.0245329 |
| ATP13A3 | ATPase type 13A3 | 0.0244305 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0243811 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0243723 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.023959 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0239191 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0238692 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0237952 |
| HMGA2 | high mobility group AT-hook 2 | 0.023534 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0230867 |
| LAMB1 | laminin, beta 1 | 0.0228279 |
| LOC112694756 | uncharaterized LOC112694756 | 0.022564 |
| NAV1 | neuron navigator 1 | 0.0225301 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0224947 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0224695 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0224418 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0223007 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0220926 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0219287 |
| SMYD3 | SET and MYND domain containing 3 | 0.0216435 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0214424 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0213654 |
| SEPTIN7 | septin 7 | 0.0210463 |
| EGFR | epidermal growth factor receptor | 0.0209032 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0208565 |
| FAM20C | family with sequence similarity 20, member C | 0.0207264 |
| VEGFC | vascular endothelial growth factor C | 0.0206563 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0203954 |
| SET | SET nuclear proto-oncogene | 0.0203819 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0202413 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0201476 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0199822 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0199496 |
| COL1A1 | collagen, type I, alpha 1 | 0.0195992 |
| JAG1 | jagged 1 | 0.0195391 |
| PLEC | plectin | 0.0195196 |
| CUX1 | cut-like homeobox 1 | 0.0193153 |
| CLIC4 | chloride intracellular channel 4 | 0.0192995 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0191683 |
| CDK13 | cyclin-dependent kinase 13 | 0.0191577 |
| AOPEP | aminopeptidase O (putative) | 0.0188364 |
| IL6ST | interleukin 6 signal transducer | 0.0187994 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0187075 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0186765 |
| GLIS3 | GLIS family zinc finger 3 | 0.0184074 |
| STC2 | stanniocalcin 2 | 0.0183325 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0181171 |
| PTPRA | protein tyrosine phosphatase, receptor type, A | 0.0180995 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0180123 |
| ANXA5 | annexin A5 | 0.0179851 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.017878 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.141214 |
| MT2A | metallothionein 2A | -0.0842041 |
| FTL | ferritin, light polypeptide | -0.0452644 |
| STC1 | stanniocalcin 1 | -0.0368593 |
| PTMA | prothymosin, alpha | -0.0321202 |
| ADM | adrenomedullin | -0.0305129 |
| CCNI | cyclin I | -0.029356 |
| MT1X | metallothionein 1X | -0.0272624 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0241753 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0240193 |
| RPLP1 | ribosomal protein, large, P1 | -0.023853 |
| TMSB10 | thymosin beta 10 | -0.0234243 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0233035 |
| PDE10A | phosphodiesterase 10A | -0.0225028 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0224411 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0218707 |
| RPS24 | ribosomal protein S24 | -0.0218071 |
| GPC6 | glypican 6 | -0.0210381 |
| CFDP1 | craniofacial development protein 1 | -0.02069 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0203349 |
| PFN1 | profilin 1 | -0.0202104 |
| RPL35A | ribosomal protein L35a | -0.0199947 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0192902 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0192698 |
| H3-3B | H3.3 histone B | -0.0191211 |
| RPS19 | ribosomal protein S19 | -0.0189823 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0188436 |
| MORF4L2 | mortality factor 4 like 2 | -0.0186268 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0183836 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0183201 |
| QKI | QKI, KH domain containing, RNA binding | -0.0178582 |
| NDRG1 | N-myc downstream regulated 1 | -0.017574 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0174172 |
| FOSL1 | FOS-like antigen 1 | -0.0173889 |
| RPL28 | ribosomal protein L28 | -0.0171619 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.016845 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0167092 |
| RPL37A | ribosomal protein L37a | -0.0166374 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0165884 |
| POM121C | POM121 transmembrane nucleoporin C | -0.0162337 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0160244 |
| RPS8 | ribosomal protein S8 | -0.0157847 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0155591 |
| RPS5 | ribosomal protein S5 | -0.0154677 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0153232 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0152906 |
| RPL12 | ribosomal protein L12 | -0.0152465 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0152096 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0151869 |
| RACK1 | receptor for activated C kinase 1 | -0.0149357 |
| RPLP2 | ribosomal protein, large, P2 | -0.0147755 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0147492 |
| PTN | pleiotrophin | -0.0146776 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.01454 |
| RASA2 | RAS p21 protein activator 2 | -0.0145381 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0145057 |
| SPAG9 | sperm associated antigen 9 | -0.0143637 |
| RPS27 | ribosomal protein S27 | -0.01426 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0142345 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0140753 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0140105 |
| SEC24B | SEC24 family member B | -0.0139195 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.013799 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0136762 |
| RPL11 | ribosomal protein L11 | -0.0135387 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0135098 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0133258 |
| HLA-E | major histocompatibility complex, class I, E | -0.0133061 |
| RPS6 | ribosomal protein S6 | -0.0132446 |
| RPL32 | ribosomal protein L32 | -0.0132441 |
| CD109 | CD109 molecule | -0.0132401 |
| JMJD1C | jumonji domain containing 1C | -0.013226 |
| FMNL2 | formin-like 2 | -0.0131987 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.013078 |
| USP36 | ubiquitin specific peptidase 36 | -0.0128866 |
| RPL37 | ribosomal protein L37 | -0.0126941 |
| RPL13A | ribosomal protein L13a | -0.0126597 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0125969 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0125387 |
| RAB8B | RAB8B, member RAS oncogene family | -0.0124908 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.012423 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0123667 |
| SEC11A | SEC11 homolog A (S. cerevisiae) | -0.0123568 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.0122337 |
| RPL38 | ribosomal protein L38 | -0.0121992 |
| ZNF207 | zinc finger protein 207 | -0.0121964 |
| RPL36 | ribosomal protein L36 | -0.0121865 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0121727 |
| ERGIC3 | ERGIC and golgi 3 | -0.0121211 |
| RNF213 | ring finger protein 213 | -0.0120215 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.012021 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.011984 |
| DTNA | dystrobrevin, alpha | -0.0119611 |
| RPL5 | ribosomal protein L5 | -0.0119514 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0119227 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0119022 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0117791 |
| MECP2 | methyl CpG binding protein 2 | -0.0116935 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0115458 |
| SECISBP2L | SECIS binding protein 2-like | -0.0114313 |
