| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Infigratinib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Infigratinib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHA | lactate dehydrogenase A | 0.17361 |
| VIM | vimentin | 0.144886 |
| FNDC3B | fibronectin type III domain containing 3B | 0.141744 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.138493 |
| HMGA2 | high mobility group AT-hook 2 | 0.103782 |
| PKM | pyruvate kinase, muscle | 0.0976285 |
| AHNAK | AHNAK nucleoprotein | 0.0898186 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0846951 |
| TMSB10 | thymosin beta 10 | 0.079572 |
| ANXA2 | annexin A2 | 0.0666962 |
| PRKCA | protein kinase C, alpha | 0.0662636 |
| ENO1 | enolase 1, (alpha) | 0.0624542 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0619077 |
| INTS6 | integrator complex subunit 6 | 0.0601891 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0596242 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.058277 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0560817 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.055418 |
| ASPH | aspartate beta-hydroxylase | 0.0540844 |
| PRSS23 | protease, serine, 23 | 0.0537385 |
| RAI14 | retinoic acid induced 14 | 0.0537096 |
| SVIL | supervillin | 0.0536192 |
| EGFR | epidermal growth factor receptor | 0.0524791 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0459887 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0454282 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0451403 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0443639 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0424503 |
| TPI1 | triosephosphate isomerase 1 | 0.0422008 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.040946 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.04076 |
| SMAD3 | SMAD family member 3 | 0.0400697 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0397268 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0395356 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0389954 |
| FMNL2 | formin-like 2 | 0.0389354 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0383463 |
| NDRG1 | N-myc downstream regulated 1 | 0.0371789 |
| ANGPTL4 | angiopoietin-like 4 | 0.0367402 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0364382 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.035588 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0344298 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.033739 |
| ITGB4 | integrin, beta 4 | 0.0333388 |
| HLA-B | major histocompatibility complex, class I, B | 0.0330695 |
| SKIL | SKI-like proto-oncogene | 0.0325525 |
| CALR | calreticulin | 0.0324937 |
| RPL35A | ribosomal protein L35a | 0.0323675 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0322806 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0322401 |
| COL5A1 | collagen, type V, alpha 1 | 0.0320784 |
| MCL1 | myeloid cell leukemia 1 | 0.0319129 |
| FLNB | filamin B, beta | 0.0318329 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.031729 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0315751 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0314337 |
| PCED1B | PC-esterase domain containing 1B | 0.0313668 |
| EGR1 | early growth response 1 | 0.0312602 |
| FMN1 | formin 1 | 0.0305607 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0301817 |
| SQSTM1 | sequestosome 1 | 0.0300781 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0295988 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.029217 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0290604 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0289244 |
| RIGI | RNA sensor RIG-I | 0.0284957 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0284884 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0281845 |
| CANX | calnexin | 0.0280849 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0280589 |
| POTEF | POTE ankyrin domain family, member F | 0.0279638 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0279287 |
| S100A10 | S100 calcium binding protein A10 | 0.0276622 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0275428 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0268645 |
| PARD3 | par-3 family cell polarity regulator | 0.0266181 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0264294 |
| DST | dystonin | 0.0263829 |
| LAMB1 | laminin, beta 1 | 0.0263105 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0260555 |
| CMIP | c-Maf inducing protein | 0.0257721 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0255345 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0254132 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0253984 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0253714 |
| RPLP1 | ribosomal protein, large, P1 | 0.0250498 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0249381 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0248975 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0248419 |
| WWOX | WW domain containing oxidoreductase | 0.0244792 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0240345 |
| EFNA5 | ephrin-A5 | 0.0239164 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0237094 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0236675 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0236169 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0235851 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0235641 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0235033 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0234401 |
| HLA-A | major histocompatibility complex, class I, A | 0.0229106 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLGA4 | golgin A4 | -0.110005 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.101478 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0894724 |
| CENPF | centromere protein F, 350/400kDa | -0.0806966 |
| RBM39 | RNA binding motif protein 39 | -0.0763172 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0689827 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0658707 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0628147 |
| YBX3 | Y box binding protein 3 | -0.0614524 |
| NUP58 | nucleoporin 58 | -0.0610933 |
| TPX2 | TPX2, microtubule-associated | -0.059915 |
| SETD5 | SET domain containing 5 | -0.0592433 |
| SPAG9 | sperm associated antigen 9 | -0.0570428 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0531798 |
| SMYD3 | SET and MYND domain containing 3 | -0.0495162 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0491131 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0490847 |
| SNX14 | sorting nexin 14 | -0.048693 |
| TXNRD1 | thioredoxin reductase 1 | -0.0483708 |
| PHF20 | PHD finger protein 20 | -0.048187 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0463961 |
| ANLN | anillin, actin binding protein | -0.0446707 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0442141 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0437799 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0436209 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0432085 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0418428 |
| CPNE1 | copine I | -0.0411686 |
| ZNF292 | zinc finger protein 292 | -0.0411523 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0404947 |
| CLTC | clathrin, heavy chain (Hc) | -0.0380434 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0380146 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0375786 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0366094 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.036348 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0354439 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0354263 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0350904 |
| RRBP1 | ribosome binding protein 1 | -0.0349058 |
| NKTR | natural killer cell triggering receptor | -0.034179 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0340644 |
| ECT2 | epithelial cell transforming 2 | -0.0334864 |
| FAM168B | family with sequence similarity 168, member B | -0.0329363 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.032697 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0311907 |
| GOLT1B | golgi transport 1B | -0.0311268 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0310389 |
| KIF4A | kinesin family member 4A | -0.0308502 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0304567 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0300362 |
| MATR3 | matrin 3 | -0.0299801 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0299779 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0298946 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0296513 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0291096 |
| DENND4A | DENN/MADD domain containing 4A | -0.0288382 |
| PRRC2C | proline-rich coiled-coil 2C | -0.028605 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0281415 |
| QKI | QKI, KH domain containing, RNA binding | -0.0279937 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0277653 |
| HMGB2 | high mobility group box 2 | -0.0276922 |
| HELZ | helicase with zinc finger | -0.0276912 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0276674 |
| PRR11 | proline rich 11 | -0.0275598 |
| RNF145 | ring finger protein 145 | -0.027422 |
| KIF5B | kinesin family member 5B | -0.0274091 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0272781 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0271914 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0266855 |
| OSBPL6 | oxysterol binding protein-like 6 | -0.0266427 |
| CEP57 | centrosomal protein 57kDa | -0.0266312 |
| TFG | TRK-fused gene | -0.0265072 |
| TFRC | transferrin receptor | -0.0264605 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0264567 |
| OGA | O-GlcNAcase | -0.0263245 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0262559 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0262041 |
| TMEM167A | transmembrane protein 167A | -0.0261631 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.026137 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.0260962 |
| AURKA | aurora kinase A | -0.0260042 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0258226 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0256118 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0255531 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0254538 |
| BRD2 | bromodomain containing 2 | -0.0252653 |
| CEP170 | centrosomal protein 170kDa | -0.0252562 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0251617 |
| RPS2 | ribosomal protein S2 | -0.0251107 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.024908 |
| ATM | ATM serine/threonine kinase | -0.0248543 |
| HJURP | Holliday junction recognition protein | -0.0246126 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.024608 |
| UBQLN1 | ubiquilin 1 | -0.0245521 |
| KIF18B | kinesin family member 18B | -0.0242825 |
| DIAPH3 | diaphanous-related formin 3 | -0.0241818 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0240738 |
| NCKAP1 | NCK-associated protein 1 | -0.0240608 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0239113 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.0238243 |
