Influenza Gene Set

Dataset DISEASES Experimental Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in infection, located_in respiratory tract, has_material_basis_in Influenzavirus A, has_material_basis_in Influenzavirus B, or has_material_basis_in Influenzavirus C, which are transmitted_by droplet spread of oronasal secretions during coughing, sneezing, or talking from an infected person. It is a highly contagious disease that affects birds and mammals and has_symptom chills, has_symptom fever, has_symptom sore throat, has_symptom runny nose, has_symptom muscle pains, has_symptom severe headache, has_symptom cough, and has_symptom weakness. (Human Disease Ontology, DOID_8469)
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Genes

69 genes associated with the disease Influenza in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
PTPRR protein tyrosine phosphatase, receptor type, R 1.758
DLG2 discs, large homolog 2 (Drosophila) 1.678
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 1.541
BAG1 BCL2-associated athanogene 1.541
CHMP5 charged multivesicular body protein 5 1.541
NFX1 nuclear transcription factor, X-box binding 1 1.541
SPINK4 serine peptidase inhibitor, Kazal type 4 1.541
SPRED2 sprouty-related, EVH1 domain containing 2 1.506
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 1.506
DMD dystrophin 1.48
GTF2IRD1 GTF2I repeat domain containing 1 1.473
GTF2I general transcription factor IIi 1.473
SERHL2 serine hydrolase-like 2 1.401
CYB5R3 cytochrome b5 reductase 3 1.401
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 1.401
ATP5MGL ATP synthase membrane subunit g like 1.401
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) 1.401
LINGO2 leucine rich repeat and Ig domain containing 2 1.399
PNLIPRP3 pancreatic lipase-related protein 3 1.396
CCDC172 coiled-coil domain containing 172 1.396
L3MBTL3 l(3)mbt-like 3 (Drosophila) 1.364
TMEM244 transmembrane protein 244 1.364
SAMD3 sterile alpha motif domain containing 3 1.364
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 1.101
DTHD1 death domain containing 1 1.101
STOX2 storkhead box 2 1.032
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 1.032
CALML6 calmodulin-like 6 0.985
PRKCZ protein kinase C, zeta 0.985
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 0.985
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.985
CFAP74 cilia and flagella associated protein 74 0.985
TMEM52 transmembrane protein 52 0.985
TEX26 testis expressed 26 0.923
MEDAG mesenteric estrogen-dependent adipogenesis 0.923
TMPRSS11F transmembrane protease, serine 11F 0.916
PRR3 proline rich 3 0.829
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.829
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.829
C6ORF136 chromosome 6 open reading frame 136 0.829
MRPS18B mitochondrial ribosomal protein S18B 0.829
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 0.829
ATAT1 alpha tubulin acetyltransferase 1 0.829
GNL1 guanine nucleotide binding protein-like 1 0.829
PDCD6IP programmed cell death 6 interacting protein 0.8
ESYT2 extended synaptotagmin-like protein 2 0.8
SCYGR4 small cysteine and glycine repeat containing 4 0.764
SCYGR3 small cysteine and glycine repeat containing 3 0.764
SCYGR2 small cysteine and glycine repeat containing 2 0.764
AGFG1 ArfGAP with FG repeats 1 0.764
GIPC2 GIPC PDZ domain containing family, member 2 0.742
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 0.742
ADAM12 ADAM metallopeptidase domain 12 0.742
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 0.731
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 0.672
SFTA2 surfactant associated 2 0.672
MUCL3 mucin like 3 0.672
VARS2 valyl-tRNA synthetase 2, mitochondrial 0.672
MUC21 mucin 21, cell surface associated 0.672
MUC22 mucin 22 0.672
ADD2 adducin 2 (beta) 0.552
CD207 CD207 molecule, langerin 0.552
FIGLA folliculogenesis specific basic helix-loop-helix 0.552
CLEC4F C-type lectin domain family 4, member F 0.552
CRY1 cryptochrome circadian clock 1 0.548
RIC8B RIC8 guanine nucleotide exchange factor B 0.548
MTERF2 mitochondrial transcription termination factor 2 0.548
TMEM263 transmembrane protein 263 0.548
ADGRL2 adhesion G protein-coupled receptor L2 0.511