Insulin Pathway Gene Set

Dataset PID Pathways
Category structural or functional annotations
Type pathway
External Link http://public.ndexbio.org/#/network/073b9f25-6194-11e5-8ac5-06603eb7f303
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Genes

43 proteins participating in the Insulin Pathway pathway from the PID Pathways dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EXOC1 exocyst complex component 1
EXOC2 exocyst complex component 2
EXOC3 exocyst complex component 3
EXOC4 exocyst complex component 4
EXOC5 exocyst complex component 5
EXOC6 exocyst complex component 6
EXOC7 exocyst complex component 7
F2RL2 coagulation factor II (thrombin) receptor-like 2
FOXO3 forkhead box O3
GRB10 growth factor receptor-bound protein 10
GRB14 growth factor receptor-bound protein 14
GRB2 growth factor receptor-bound protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
INS insulin
INSR insulin receptor
IRS1 insulin receptor substrate 1
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
PARD6A par-6 family cell polarity regulator alpha
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRKCI protein kinase C, iota
PRKCZ protein kinase C, zeta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPRA protein tyrosine phosphatase, receptor type, A
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RHOQ ras homolog family member Q
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SGK1 serum/glucocorticoid regulated kinase 1
SH2B2 SH2B adaptor protein 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SORBS1 sorbin and SH3 domain containing 1
SOS1 son of sevenless homolog 1 (Drosophila)
TRIP10 thyroid hormone receptor interactor 10