Insulinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A benign tumor of the PANCREATIC BETA CELLS. Insulinoma secretes excess INSULIN resulting in HYPOGLYCEMIA.|A usually benign, well circumscribed neoplasm arising from the beta cells of the pancreas. Patients exhibit symptoms related to hypoglycemia due to inappropriate secretion of insulin. (Experimental Factor Ontology, EFO_0000549)
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Genes

545 genes co-occuring with the disease Insulinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
INS insulin 3.62
MEN1 multiple endocrine neoplasia I 3.455
SLC30A10 solute carrier family 30, member 10 3.308
SLC30A8 solute carrier family 30 (zinc transporter), member 8 3.305
SST somatostatin 3.28
GCG glucagon 3.267
PTPRN protein tyrosine phosphatase, receptor type, N 3.151
GAST gastrin 2.975
PPY pancreatic polypeptide 2.968
CHGA chromogranin A 2.938
GLP1R glucagon-like peptide 1 receptor 2.819
IAPP islet amyloid polypeptide 2.744
SSTR2 somatostatin receptor 2 2.705
VIP vasoactive intestinal peptide 2.704
NIT1 nitrilase 1 2.69
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 2.661
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 2.595
SSTR5 somatostatin receptor 5 2.547
SYP synaptophysin 2.497
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 2.464
POMC proopiomelanocortin 2.457
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 2.449
GCK glucokinase (hexokinase 4) 2.432
DAXX death-domain associated protein 2.427
IGF2 insulin-like growth factor 2 2.424
PDX1 pancreatic and duodenal homeobox 1 2.396
NKX6-1 NK6 homeobox 1 2.395
NEUROG3 neurogenin 3 2.375
SCT secretin 2.356
SSTR1 somatostatin receptor 1 2.355
INSR insulin receptor 2.331
NEUROD1 neuronal differentiation 1 2.33
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 2.308
NKX6-2 NK6 homeobox 2 2.307
INSM1 insulinoma-associated 1 2.292
CPE carboxypeptidase E 2.273
PAX4 paired box 4 2.265
IGF1 insulin-like growth factor 1 (somatomedin C) 2.235
ATRX alpha thalassemia/mental retardation syndrome X-linked 2.233
MTOR mechanistic target of rapamycin (serine/threonine kinase) 2.214
PRL prolactin 2.18
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.156
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.138
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 2.115
FFAR1 free fatty acid receptor 1 2.107
ENO2 enolase 2 (gamma, neuronal) 2.094
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 2.082
SSTR4 somatostatin receptor 4 2.075
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 2.075
G6PC2 glucose-6-phosphatase, catalytic, 2 2.036
ALB albumin 2.023
SSTR3 somatostatin receptor 3 2.018
PCSK2 proprotein convertase subtilisin/kexin type 2 2.004
NTS neurotensin 1.989
GIP gastric inhibitory polypeptide 1.981
GHRH growth hormone releasing hormone 1.97
CHGB chromogranin B 1.966
IRS2 insulin receptor substrate 2 1.955
IL1B interleukin 1, beta 1.946
PTH parathyroid hormone 1.945
HNF1A HNF1 homeobox A 1.945
DPP4 dipeptidyl-peptidase 4 1.938
IFNG interferon, gamma 1.938
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.935
INSM2 insulinoma-associated 2 1.935
FOXO1 forkhead box O1 1.932
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.93
GHRL ghrelin/obestatin prepropeptide 1.921
YY1 YY1 transcription factor 1.921
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.914
NKX2-2 NK2 homeobox 2 1.906
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.894
TSC2 tuberous sclerosis 2 1.891
TP53 tumor protein p53 1.89
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.873
NF1 neurofibromin 1 1.871
GIPR gastric inhibitory polypeptide receptor 1.867
ISL1 ISL LIM homeobox 1 1.865
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.863
PAX6 paired box 6 1.854
FOXM1 forkhead box M1 1.85
JUND jun D proto-oncogene 1.846
FOXA2 forkhead box A2 1.845
ACTB actin, beta 1.831
TPO thyroid peroxidase 1.829
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.825
SCGN secretagogin, EF-hand calcium binding protein 1.812
ERN1 endoplasmic reticulum to nucleus signaling 1 1.806
WFS1 Wolfram syndrome 1 (wolframin) 1.803
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 1.792
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.79
BCL2 B-cell CLL/lymphoma 2 1.789
IRS1 insulin receptor substrate 1 1.787
GCGR glucagon receptor 1.782
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.781
TG thyroglobulin 1.78
TNF tumor necrosis factor 1.78
CD8A CD8a molecule 1.777
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1.774
PTHLH parathyroid hormone-like hormone 1.773
RAB3A RAB3A, member RAS oncogene family 1.77
NCAM1 neural cell adhesion molecule 1 1.762
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.761
ICA1 islet cell autoantigen 1, 69kDa 1.755
PXDNL peroxidasin-like 1.748
PXDN peroxidasin 1.743
CCK cholecystokinin 1.742
GRP gastrin-releasing peptide 1.741
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1.74
CD4 CD4 molecule 1.737
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.737
GLIS3 GLIS family zinc finger 3 1.733
CDKN2A cyclin-dependent kinase inhibitor 2A 1.724
TOR1A torsin family 1, member A (torsin A) 1.716
CCKBR cholecystokinin B receptor 1.716
JUN jun proto-oncogene 1.715
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.71
ATF6 activating transcription factor 6 1.708
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.705
CCND1 cyclin D1 1.704
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.704
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.703
PTEN phosphatase and tensin homolog 1.7
PCSK1 proprotein convertase subtilisin/kexin type 1 1.697
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.696
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 1.684
SCG3 secretogranin III 1.674
BTC betacellulin 1.671
LEP leptin 1.671
GJD2 gap junction protein, delta 2, 36kDa 1.664
PPARG peroxisome proliferator-activated receptor gamma 1.659
TGFB1 transforming growth factor, beta 1 1.651
XBP1 X-box binding protein 1 1.65
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.65
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 1.644
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.643
IL6 interleukin 6 1.635
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.633
INS-IGF2 INS-IGF2 readthrough 1.623
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.622
CASR calcium-sensing receptor 1.621
MGAM maltase-glucoamylase 1.621
SI sucrase-isomaltase (alpha-glucosidase) 1.617
NPY neuropeptide Y 1.605
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 1.604
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1.595
VGF VGF nerve growth factor inducible 1.588
SNAP25 synaptosomal-associated protein, 25kDa 1.583
CSH2 chorionic somatomammotropin hormone 2 1.58
DDIT3 DNA-damage-inducible transcript 3 1.579
EGF epidermal growth factor 1.575
MNX1 motor neuron and pancreas homeobox 1 1.574
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.57
IGFBP3 insulin-like growth factor binding protein 3 1.56
CREB1 cAMP responsive element binding protein 1 1.558
MAPK3 mitogen-activated protein kinase 3 1.551
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.546
H3-3B H3.3 histone B 1.544
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 1.543
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.541
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.538
RET ret proto-oncogene 1.534
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 1.533
MUTYH mutY homolog 1.53
IGF1R insulin-like growth factor 1 receptor 1.524
CDC73 cell division cycle 73 1.522
SCG2 secretogranin II 1.518
PC pyruvate carboxylase 1.512
TXNIP thioredoxin interacting protein 1.506
SNED1 sushi, nidogen and EGF-like domains 1 1.505
KRAS Kirsten rat sarcoma viral oncogene homolog 1.5
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.497
IL10 interleukin 10 1.495
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.494
UCN3 urocortin 3 1.491
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.481
BAX BCL2-associated X protein 1.481
MLXIPL MLX interacting protein-like 1.48
TGM2 transglutaminase 2 1.479
H3-4 H3.4 histone, cluster member 1.476
HRH2 histamine receptor H2 1.475
EGFR epidermal growth factor receptor 1.473
SSR2 signal sequence receptor, beta (translocon-associated protein beta) 1.471
GPSM2 G-protein signaling modulator 2 1.47
H3C12 H3 clustered histone 12 1.469
PTF1A pancreas specific transcription factor, 1a 1.468
CDK4 cyclin-dependent kinase 4 1.467
FOXN3 forkhead box N3 1.467
PNPLA8 patatin-like phospholipase domain containing 8 1.467
TAC1 tachykinin, precursor 1 1.466
H3-5 H3.5 histone 1.465
BCL2L1 BCL2-like 1 1.464
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.464
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.463
CYCS cytochrome c, somatic 1.459
GPR119 G protein-coupled receptor 119 1.459
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.457
H3C13 H3 clustered histone 13 1.452
ONECUT1 one cut homeobox 1 1.451
IFNA1 interferon, alpha 1 1.45
LOX lysyl oxidase 1.435
TSC1 tuberous sclerosis 1 1.431
IL2 interleukin 2 1.429
ADM adrenomedullin 1.425
MRPS31 mitochondrial ribosomal protein S31 1.425
SMAD4 SMAD family member 4 1.422
ANXA5 annexin A5 1.422
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.418
KDR kinase insert domain receptor 1.417
CALML6 calmodulin-like 6 1.415
CALML4 calmodulin-like 4 1.415
CD274 CD274 molecule 1.415
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.413
CALML3 calmodulin-like 3 1.413
CALML5 calmodulin-like 5 1.412
TSPAN7 tetraspanin 7 1.41
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 1.41
ADCY1 adenylate cyclase 1 (brain) 1.41
CCND2 cyclin D2 1.405
ARX aristaless related homeobox 1.404
SYTL4 synaptotagmin-like 4 1.401
KRT19 keratin 19, type I 1.401
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.396
ELAVL4 ELAV like neuron-specific RNA binding protein 4 1.396
CRH corticotropin releasing hormone 1.39
STX1A syntaxin 1A (brain) 1.39
RFX6 regulatory factor X, 6 1.387
ADIPOQ adiponectin, C1Q and collagen domain containing 1.386
MTPN myotrophin 1.385
CCL2 chemokine (C-C motif) ligand 2 1.381
CCNL2 cyclin L2 1.379
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 1.378
ASCL1 achaete-scute family bHLH transcription factor 1 1.378
CDX2 caudal type homeobox 2 1.376
PPARA peroxisome proliferator-activated receptor alpha 1.376
SREBF1 sterol regulatory element binding transcription factor 1 1.375
G6PC3 glucose 6 phosphatase, catalytic, 3 1.374
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.369
HNF4A hepatocyte nuclear factor 4, alpha 1.369
GRPR gastrin-releasing peptide receptor 1.367
GJA4 gap junction protein, alpha 4, 37kDa 1.365
PECAM1 platelet/endothelial cell adhesion molecule 1 1.361
ATF4 activating transcription factor 4 1.36
KMT2A lysine (K)-specific methyltransferase 2A 1.358
REG3A regenerating islet-derived 3 alpha 1.356
TEK TEK tyrosine kinase, endothelial 1.355
SIRT1 sirtuin 1 1.354
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.353
DNAH8 dynein, axonemal, heavy chain 8 1.351
CXCL12 chemokine (C-X-C motif) ligand 12 1.351
CXCR4 chemokine (C-X-C motif) receptor 4 1.348
FOXP3 forkhead box P3 1.348
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 1.339
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 1.338
DEPDC5 DEP domain containing 5 1.336
REM2 RAS (RAD and GEM)-like GTP binding 2 1.328
GSK3B glycogen synthase kinase 3 beta 1.325
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.324
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.322
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 1.321
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 1.319
LEPR leptin receptor 1.315
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.311
MGMT O-6-methylguanine-DNA methyltransferase 1.31
MLN motilin 1.308
TSHR thyroid stimulating hormone receptor 1.307
KDM6A lysine (K)-specific demethylase 6A 1.307
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.302
CLTRN collectrin, amino acid transport regulator 1.302
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1.302
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.302
RPH3AL rabphilin 3A-like (without C2 domains) 1.299
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 1.296
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.289
REN renin 1.287
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.285
IL1A interleukin 1, alpha 1.28
ERBB2 erb-b2 receptor tyrosine kinase 2 1.28
TRPM3 transient receptor potential cation channel, subfamily M, member 3 1.28
TLR4 toll-like receptor 4 1.278
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.277
TRPM2 transient receptor potential cation channel, subfamily M, member 2 1.273
TXN thioredoxin 1.272
MET MET proto-oncogene, receptor tyrosine kinase 1.267
PCNA proliferating cell nuclear antigen 1.264
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.264
RPS15 ribosomal protein S15 1.263
GLB1 galactosidase, beta 1 1.261
SYT7 synaptotagmin VII 1.26
ARRB1 arrestin, beta 1 1.254
HNF1B HNF1 homeobox B 1.253
SCG5 secretogranin V 1.251
PYY peptide YY 1.248
FOS FBJ murine osteosarcoma viral oncogene homolog 1.246
FGF2 fibroblast growth factor 2 (basic) 1.246
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.246
CDK2 cyclin-dependent kinase 2 1.246
HADH hydroxyacyl-CoA dehydrogenase 1.245
ESR1 estrogen receptor 1 1.245
FN1 fibronectin 1 1.242
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.241
PTPRC protein tyrosine phosphatase, receptor type, C 1.235
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.235
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.234
IL4 interleukin 4 1.231
CDK6 cyclin-dependent kinase 6 1.231
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 1.23
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.226
IFNA2 interferon, alpha 2 1.225
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.224
ANGPT2 angiopoietin 2 1.224
GH1 growth hormone 1 1.223
STC1 stanniocalcin 1 1.223
CHEK2 checkpoint kinase 2 1.222
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.222
FLT1 fms-related tyrosine kinase 1 1.221
MADD MAP-kinase activating death domain 1.22
PKM pyruvate kinase, muscle 1.22
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.219
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.219
BRCA2 breast cancer 2, early onset 1.213
POU3F4 POU class 3 homeobox 4 1.212
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.209
PRMT5 protein arginine methyltransferase 5 1.205
GNAS GNAS complex locus 1.205
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.205
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.202
ERO1B endoplasmic reticulum oxidoreductase 1 beta 1.201
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 1.2
CLEC16A C-type lectin domain family 16, member A 1.199
MCU mitochondrial calcium uniporter 1.197
HSPA4 heat shock 70kDa protein 4 1.194
GCKR glucokinase (hexokinase 4) regulator 1.193
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 1.192
CALR calreticulin 1.191
STK11 serine/threonine kinase 11 1.188
SYT4 synaptotagmin IV 1.184
MMP9 matrix metallopeptidase 9 1.181
TRPM5 transient receptor potential cation channel, subfamily M, member 5 1.175
RPS6 ribosomal protein S6 1.174
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 1.173
ATM ATM serine/threonine kinase 1.173
RPTOR regulatory associated protein of MTOR, complex 1 1.172
FGF4 fibroblast growth factor 4 1.171
RAB27A RAB27A, member RAS oncogene family 1.17
CRP C-reactive protein, pentraxin-related 1.17
IL17A interleukin 17A 1.168
FGF17 fibroblast growth factor 17 1.167
CTRB1 chymotrypsinogen B1 1.166
GATA6 GATA binding protein 6 1.166
TPH1 tryptophan hydroxylase 1 1.162
GPX2 glutathione peroxidase 2 1.161
SMAD3 SMAD family member 3 1.16
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 1.158
FGF7 fibroblast growth factor 7 1.157
HYOU1 hypoxia up-regulated 1 1.156
CARTPT CART prepropeptide 1.156
CXCL8 chemokine (C-X-C motif) ligand 8 1.152
MAPK8 mitogen-activated protein kinase 8 1.152
FGF10 fibroblast growth factor 10 1.152
SOX9 SRY (sex determining region Y)-box 9 1.151
CXCL10 chemokine (C-X-C motif) ligand 10 1.15
GAS1 growth arrest-specific 1 1.149
HDAC1 histone deacetylase 1 1.148
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 1.146
CCNA2 cyclin A2 1.146
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.146
GPX3 glutathione peroxidase 3 1.145
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 1.145
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.145
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 1.144
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 1.142
GPX7 glutathione peroxidase 7 1.141
FGF18 fibroblast growth factor 18 1.14
FGF5 fibroblast growth factor 5 1.14
SNAI1 snail family zinc finger 1 1.14
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.139
ARRB2 arrestin, beta 2 1.138
CELA1 chymotrypsin-like elastase family, member 1 1.137
GPX8 glutathione peroxidase 8 (putative) 1.136
GPX5 glutathione peroxidase 5 1.136
SELL selectin L 1.135
PARP1 poly (ADP-ribose) polymerase 1 1.133
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.133
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.132
CAV1 caveolin 1, caveolae protein, 22kDa 1.132
AMY2A amylase, alpha 2A (pancreatic) 1.131
PRLR prolactin receptor 1.13
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 1.129
BRAF B-Raf proto-oncogene, serine/threonine kinase 1.128
FGF3 fibroblast growth factor 3 1.127
STAT5A signal transducer and activator of transcription 5A 1.127
FGF22 fibroblast growth factor 22 1.126
HDAC9 histone deacetylase 9 1.125
FURIN furin (paired basic amino acid cleaving enzyme) 1.124
FGF6 fibroblast growth factor 6 1.124
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 1.124
GPX6 glutathione peroxidase 6 1.122
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.122
HLA-A major histocompatibility complex, class I, A 1.122
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.121
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 1.121
DLK1 delta-like 1 homolog (Drosophila) 1.12
IFNA17 interferon, alpha 17 1.12
CCKAR cholecystokinin A receptor 1.119
FGF16 fibroblast growth factor 16 1.116
FGF13 fibroblast growth factor 13 1.116
SOX6 SRY (sex determining region Y)-box 6 1.115
FGF9 fibroblast growth factor 9 1.115
PRKCZ protein kinase C, zeta 1.115
HMOX1 heme oxygenase 1 1.115
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 1.114
FGF20 fibroblast growth factor 20 1.113
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.113
INA internexin neuronal intermediate filament protein, alpha 1.111
PDCD1 programmed cell death 1 1.111
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.111
CD44 CD44 molecule (Indian blood group) 1.111
NFE2L2 nuclear factor, erythroid 2-like 2 1.108
CD80 CD80 molecule 1.107
HRG histidine-rich glycoprotein 1.107
SNAPIN SNAP-associated protein 1.107
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.106
CELA3B chymotrypsin-like elastase family, member 3B 1.106
GLUD1 glutamate dehydrogenase 1 1.103
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.103
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.102
CDH5 cadherin 5, type 2 (vascular endothelium) 1.1
CORT cortistatin 1.099
GAL galanin/GMAP prepropeptide 1.099
CCL28 chemokine (C-C motif) ligand 28 1.099
IFNA4 interferon, alpha 4 1.098
VIPR1 vasoactive intestinal peptide receptor 1 1.095
SHH sonic hedgehog 1.095
IFNA14 interferon, alpha 14 1.094
FGF8 fibroblast growth factor 8 (androgen-induced) 1.093
PGF placental growth factor 1.091
MTNR1B melatonin receptor 1B 1.09
IFNA16 interferon, alpha 16 1.085
IFNA10 interferon, alpha 10 1.084
IFNA21 interferon, alpha 21 1.084
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 1.084
SETD2 SET domain containing 2 1.084
IFNA7 interferon, alpha 7 1.084
VEGFC vascular endothelial growth factor C 1.084
IFNA8 interferon, alpha 8 1.083
IFNA6 interferon, alpha 6 1.083
CPA1 carboxypeptidase A1 (pancreatic) 1.083
IFNA5 interferon, alpha 5 1.082
TCHP trichoplein, keratin filament binding 1.082
IPMK inositol polyphosphate multikinase 1.082
PRDX4 peroxiredoxin 4 1.081
IFNA13 interferon, alpha 13 1.081
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 1.08
RYR2 ryanodine receptor 2 (cardiac) 1.078
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.077
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 1.077
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.076
STAT5B signal transducer and activator of transcription 5B 1.075
TFAM transcription factor A, mitochondrial 1.075
SH2B3 SH2B adaptor protein 3 1.073
GCM2 glial cells missing homolog 2 (Drosophila) 1.072
ICAM1 intercellular adhesion molecule 1 1.072
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.072
KMT2C lysine (K)-specific methyltransferase 2C 1.072
CSN2 casein beta 1.071
CD34 CD34 molecule 1.071
CANX calnexin 1.07
REG1A regenerating islet-derived 1 alpha 1.07
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.068
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 1.067
BECN1 beclin 1, autophagy related 1.067
CD68 CD68 molecule 1.067
FASLG Fas ligand (TNF superfamily, member 6) 1.066
IL2RA interleukin 2 receptor, alpha 1.066
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.066
SYCN syncollin 1.065
KCNK16 potassium channel, two pore domain subfamily K, member 16 1.065
IGF2R insulin-like growth factor 2 receptor 1.063
BRS3 bombesin-like receptor 3 1.063
CD86 CD86 molecule 1.063
LAMP1 lysosomal-associated membrane protein 1 1.062
ACLY ATP citrate lyase 1.062
MME membrane metallo-endopeptidase 1.062
MYD88 myeloid differentiation primary response 88 1.061
RYR1 ryanodine receptor 1 (skeletal) 1.061
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 1.06
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 1.06
FFAR4 free fatty acid receptor 4 1.059
TTR transthyretin 1.057
MFN2 mitofusin 2 1.055
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.054
HIC1 hypermethylated in cancer 1 1.053
LPL lipoprotein lipase 1.053
SSR1 signal sequence receptor, alpha 1.053
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 1.053
PRDM2 PR domain containing 2, with ZNF domain 1.053
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.052
SOD2 superoxide dismutase 2, mitochondrial 1.049
FOXO3 forkhead box O3 1.048
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.048
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.047
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.046
ATG7 autophagy related 7 1.046
TGFA transforming growth factor, alpha 1.045
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.045
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.044
RHEB Ras homolog enriched in brain 1.042
MMP2 matrix metallopeptidase 2 1.041
CPB1 carboxypeptidase B1 (tissue) 1.04
CTRB2 chymotrypsinogen B2 1.039
CSF1 colony stimulating factor 1 (macrophage) 1.039
MANF mesencephalic astrocyte-derived neurotrophic factor 1.038
ULK1 unc-51 like autophagy activating kinase 1 1.036
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.033
VCAM1 vascular cell adhesion molecule 1 1.033
TGOLN2 trans-golgi network protein 2 1.033
CD40 CD40 molecule, TNF receptor superfamily member 5 1.032
RETNLB resistin like beta 1.031
UNC13B unc-13 homolog B (C. elegans) 1.029
IDE insulin-degrading enzyme 1.029
TERT telomerase reverse transcriptase 1.029
FLT4 fms-related tyrosine kinase 4 1.028
MLH1 mutL homolog 1 1.026
S100G S100 calcium binding protein G 1.024
PRDX1 peroxiredoxin 1 1.024
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 1.024
ATG5 autophagy related 5 1.022
TBC1D4 TBC1 domain family, member 4 1.022
PEBP1 phosphatidylethanolamine binding protein 1 1.022
PYGL phosphorylase, glycogen, liver 1.021
THBS1 thrombospondin 1 1.019
CSF1R colony stimulating factor 1 receptor 1.016
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.013
CDK1 cyclin-dependent kinase 1 1.013
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) 1.01
CYBB cytochrome b-245, beta polypeptide 1.01
CNR1 cannabinoid receptor 1 (brain) 1.008
CCND3 cyclin D3 1.007
VWA5A von Willebrand factor A domain containing 5A 1.005
SOX13 SRY (sex determining region Y)-box 13 1.003
LMAN1 lectin, mannose-binding, 1 1.002
EIF4E eukaryotic translation initiation factor 4E 1.002
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 1.001
SYPL1 synaptophysin-like 1 1.0