Integrated Cancer pathway(Homo sapiens) Gene Set
Genes
35 proteins participating in the Integrated Cancer pathway(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.
| Symbol |
Name |
|
AKT1
|
v-akt murine thymoma viral oncogene homolog 1
|
|
ATM
|
ATM serine/threonine kinase
|
|
ATR
|
ATR serine/threonine kinase
|
|
BAD
|
BCL2-associated agonist of cell death
|
|
BARD1
|
BRCA1 associated RING domain 1
|
|
BAX
|
BCL2-associated X protein
|
|
BCL2
|
B-cell CLL/lymphoma 2
|
|
BLM
|
Bloom syndrome, RecQ helicase-like
|
|
BRCA1
|
breast cancer 1, early onset
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
|
CASP8
|
caspase 8, apoptosis-related cysteine peptidase
|
|
CASP9
|
caspase 9, apoptosis-related cysteine peptidase
|
|
CDC25A
|
cell division cycle 25A
|
|
CDC25B
|
cell division cycle 25B
|
|
CDK1
|
cyclin-dependent kinase 1
|
|
CDK2
|
cyclin-dependent kinase 2
|
|
CDK4
|
cyclin-dependent kinase 4
|
|
CHEK1
|
checkpoint kinase 1
|
|
CHEK2
|
checkpoint kinase 2
|
|
E2F1
|
E2F transcription factor 1
|
|
JAK1
|
Janus kinase 1
|
|
MDM2
|
MDM2 proto-oncogene, E3 ubiquitin protein ligase
|
|
MMP1
|
matrix metallopeptidase 1
|
|
MRE11A
|
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
|
|
MSH2
|
mutS homolog 2
|
|
MSH6
|
mutS homolog 6
|
|
NOXA1
|
NADPH oxidase activator 1
|
|
PLK1
|
polo-like kinase 1
|
|
PTEN
|
phosphatase and tensin homolog
|
|
RAD50
|
RAD50 homolog (S. cerevisiae)
|
|
RB1
|
retinoblastoma 1
|
|
SMAD2
|
SMAD family member 2
|
|
SMAD3
|
SMAD family member 3
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
|
TP53
|
tumor protein p53
|
