Integrated cancer pathway Gene Set

Dataset WikiPathways Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://www.wikipathways.org/pathways/WP1971.html
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Genes

44 proteins participating in the Integrated cancer pathway pathway from the WikiPathways Pathways 2024 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATF1 activating transcription factor 1
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAD BCL2-associated agonist of cell death
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
E2F1 E2F transcription factor 1
JAK1 Janus kinase 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP1 matrix metallopeptidase 1
MRE11 MRE11 homolog, double strand break repair nuclease
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOXA1 NADPH oxidase activator 1
PLK1 polo-like kinase 1
POU2F1 POU class 2 homeobox 1
PTEN phosphatase and tensin homolog
RAD50 RAD50 homolog (S. cerevisiae)
RB1 retinoblastoma 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
STAT1 signal transducer and activator of transcription 1, 91kDa
TP53 tumor protein p53