Interferon regulatory factor 3-interferon regulatory factor 7 complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 7. (Gene Ontology, GO_0097075)
External Link http://amigo.geneontology.org/amigo/term/GO:0097075
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Genes

117 proteins co-occuring with the Interferon regulatory factor 3-interferon regulatory factor 7 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
IRF7 interferon regulatory factor 7 1.775
MAP3K8 mitogen-activated protein kinase kinase kinase 8 1.651
IRF3 interferon regulatory factor 3 1.608
TBKBP1 TBK1 binding protein 1 1.574
UBE2E1 ubiquitin-conjugating enzyme E2E 1 1.501
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.489
EIF4E2 eukaryotic translation initiation factor 4E family member 2 1.474
SP100 SP100 nuclear antigen 1.439
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.423
CHMP5 charged multivesicular body protein 5 1.363
RNF182 ring finger protein 182 1.288
RIGI RNA sensor RIG-I 1.27
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.24
RNF166 ring finger protein 166 1.218
ISG15 ISG15 ubiquitin-like modifier 1.212
IFNB1 interferon, beta 1, fibroblast 1.209
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 1.207
UBE2N ubiquitin-conjugating enzyme E2N 1.204
LIMD2 LIM domain containing 2 1.177
IFIH1 interferon induced with helicase C domain 1 1.153
TANK TRAF family member-associated NFKB activator 1.124
ZCCHC3 zinc finger, CCHC domain containing 3 1.111
SCIMP SLP adaptor and CSK interacting membrane protein 1.102
MKRN2 makorin ring finger protein 2 1.097
RNF170 ring finger protein 170 1.089
PML promyelocytic leukemia 1.054
TP63 tumor protein p63 1.049
GBP6 guanylate binding protein family, member 6 1.037
TLR7 toll-like receptor 7 1.036
WDFY1 WD repeat and FYVE domain containing 1 1.02
TRIM25 tripartite motif containing 25 1.017
IQGAP1 IQ motif containing GTPase activating protein 1 1.002
MEX3B mex-3 RNA binding family member B 0.982
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.976
DUSP14 dual specificity phosphatase 14 0.953
TRIM26 tripartite motif containing 26 0.937
TLR1 toll-like receptor 1 0.935
FLNB filamin B, beta 0.923
TRMT6 tRNA methyltransferase 6 0.919
OTUD1 OTU deubiquitinase 1 0.916
TLR8 toll-like receptor 8 0.914
TRIM23 tripartite motif containing 23 0.901
SP140 SP140 nuclear body protein 0.889
ATL1 atlastin GTPase 1 0.888
NLRP10 NLR family, pyrin domain containing 10 0.877
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.872
TRIM38 tripartite motif containing 38 0.87
PLCG1 phospholipase C, gamma 1 0.868
SRFBP1 serum response factor binding protein 1 0.841
TRAF1 TNF receptor-associated factor 1 0.832
TRAF3 TNF receptor-associated factor 3 0.831
OTUD5 OTU deubiquitinase 5 0.83
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 0.828
IFNA1 interferon, alpha 1 0.816
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 0.811
SOAT2 sterol O-acyltransferase 2 0.81
LRR1 leucine rich repeat protein 1 0.809
PDLIM2 PDZ and LIM domain 2 (mystique) 0.807
RARA retinoic acid receptor, alpha 0.796
MX1 MX dynamin-like GTPase 1 0.794
TLR3 toll-like receptor 3 0.791
TBK1 TANK-binding kinase 1 0.782
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.771
H2AC1 H2A clustered histone 1 0.769
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 0.766
IFITM3 interferon induced transmembrane protein 3 0.758
TRIM3 tripartite motif containing 3 0.75
STAT1 signal transducer and activator of transcription 1, 91kDa 0.732
TRIM29 tripartite motif containing 29 0.721
UBA7 ubiquitin-like modifier activating enzyme 7 0.719
USP19 ubiquitin specific peptidase 19 0.714
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.703
E2F8 E2F transcription factor 8 0.703
TRIM27 tripartite motif containing 27 0.699
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 0.687
CDC6 cell division cycle 6 0.682
IRF9 interferon regulatory factor 9 0.679
CDCA5 cell division cycle associated 5 0.671
CCNE1 cyclin E1 0.668
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.666
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 0.665
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.661
IFNE interferon, epsilon 0.654
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.645
IFNK interferon, kappa 0.642
JAK1 Janus kinase 1 0.635
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 0.629
GBP5 guanylate binding protein 5 0.627
E2F7 E2F transcription factor 7 0.627
USP2 ubiquitin specific peptidase 2 0.625
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 0.611
PRKN parkin RBR E3 ubiquitin protein ligase 0.61
TSG101 tumor susceptibility 101 0.607
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.599
IFI44 interferon-induced protein 44 0.594
ISG20 interferon stimulated exonuclease gene 20kDa 0.592
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 0.588
CTTNBP2 cortactin binding protein 2 0.586
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 0.575
TRIM8 tripartite motif containing 8 0.564
DHCR24 24-dehydrocholesterol reductase 0.56
MYD88 myeloid differentiation primary response 88 0.56
GBP2 guanylate binding protein 2, interferon-inducible 0.546
OASL 2'-5'-oligoadenylate synthetase-like 0.543
SCD5 stearoyl-CoA desaturase 5 0.541
LYN LYN proto-oncogene, Src family tyrosine kinase 0.54
TLR2 toll-like receptor 2 0.539
TRIM31 tripartite motif containing 31 0.532
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.527
TICAM1 toll-like receptor adaptor molecule 1 0.523
CXCL2 chemokine (C-X-C motif) ligand 2 0.519
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.518
UNC93B1 unc-93 homolog B1 (C. elegans) 0.516
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.512
USP18 ubiquitin specific peptidase 18 0.511
GADD45G growth arrest and DNA-damage-inducible, gamma 0.506
KIF20A kinesin family member 20A 0.506