Interleukin-1 signaling Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-9020702
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Genes

101 proteins participating in the Interleukin-1 signaling pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ADRM1 adhesion regulating molecule 1
AGER advanced glycosylation end product-specific receptor
ALPK1 alpha-kinase 1
APP amyloid beta (A4) precursor protein
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CHUK conserved helix-loop-helix ubiquitous kinase
CUL1 cullin 1
FBXW11 F-box and WD repeat domain containing 11
HMGB1 high mobility group box 1
IKBIP IKBKB interacting protein
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
IL1RAP interleukin 1 receptor accessory protein
IL1RN interleukin 1 receptor antagonist
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
LRRC14 leucine rich repeat containing 14
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MYD88 myeloid differentiation primary response 88
N4BP1 NEDD4 binding protein 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NKIRAS1 NFKB inhibitor interacting Ras-like 1
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NLRC5 NLR family, CARD domain containing 5
NLRX1 NLR family member X1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
PELI1 pellino E3 ubiquitin protein ligase 1
PELI2 pellino E3 ubiquitin protein ligase family member 2
PELI3 pellino E3 ubiquitin protein ligase family member 3
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
RBX1 ring-box 1, E3 ubiquitin protein ligase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RIPK2 receptor-interacting serine-threonine kinase 2
RPS27A ribosomal protein S27a
S100A12 S100 calcium binding protein A12
S100B S100 calcium binding protein B
SAA1 serum amyloid A1
SEM1 SEM1 26S proteasome subunit
SKP1 S-phase kinase-associated protein 1
SQSTM1 sequestosome 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TIFA TRAF-interacting protein with forkhead-associated domain
TNIP2 TNFAIP3 interacting protein 2
TOLLIP toll interacting protein
TP53 tumor protein p53
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP18 ubiquitin specific peptidase 18