Interleukin-4 and Interleukin-13 signaling Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-6785807
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Genes

108 proteins participating in the Interleukin-4 and Interleukin-13 signaling pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX15 arachidonate 15-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ANXA1 annexin A1
BATF basic leucine zipper transcription factor, ATF-like
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL6 B-cell CLL/lymphoma 6
BIRC5 baculoviral IAP repeat containing 5
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL22 chemokine (C-C motif) ligand 22
CCND1 cyclin D1
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
COL1A2 collagen, type I, alpha 2
CXCL8 chemokine (C-X-C motif) ligand 8
F13A1 coagulation factor XIII, A1 polypeptide
FASLG Fas ligand (TNF superfamily, member 6)
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FGF2 fibroblast growth factor 2 (basic)
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FSCN1 fascin actin-bundling protein 1
GATA3 GATA binding protein 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA8 heat shock 70kDa protein 8
ICAM1 intercellular adhesion molecule 1
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL13RA2 interleukin 13 receptor, alpha 2
IL17A interleukin 17A
IL17F interleukin 17F
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL2RG interleukin 2 receptor, gamma
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL6R interleukin 6 receptor
IRF4 interferon regulatory factor 4
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JUNB jun B proto-oncogene
LAMA5 laminin, alpha 5
LBP lipopolysaccharide binding protein
LCN2 lipocalin 2
LIF leukemia inhibitory factor
MAOA monoamine oxidase A
MCL1 myeloid cell leukemia 1
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NANOG Nanog homeobox
NDN necdin, melanoma antigen (MAGE) family member
NOS2 nitric oxide synthase 2, inducible
OPRD1 opioid receptor, delta 1
OPRM1 opioid receptor, mu 1
OSM oncostatin M
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
POMC proopiomelanocortin
POU2F1 POU class 2 homeobox 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RHOU ras homolog family member U
RORA RAR-related orphan receptor A
RORC RAR-related orphan receptor C
S1PR1 sphingosine-1-phosphate receptor 1
SAA1 serum amyloid A1
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOCS5 suppressor of cytokine signaling 5
SOX2 SRY (sex determining region Y)-box 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TGFB1 transforming growth factor, beta 1
TIMP1 TIMP metallopeptidase inhibitor 1
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TP53 tumor protein p53
TWIST1 twist family bHLH transcription factor 1
TYK2 tyrosine kinase 2
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VIM vimentin
ZEB1 zinc finger E-box binding homeobox 1