Intestinal Cancer Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A gastrointestinal system cancer that is located_in the intestine. (Human Disease Ontology, DOID_10155)
External Link https://www.disgenet.org/browser/0/1/0/C0346627
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Genes

83 genes associated with the disease Intestinal Cancer in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ADIPOQ adiponectin, C1Q and collagen domain containing
APC adenomatous polyposis coli
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BOK BCL2-related ovarian killer
BRAF B-Raf proto-oncogene, serine/threonine kinase
CCK cholecystokinin
CCKBR cholecystokinin B receptor
CCR7 chemokine (C-C motif) receptor 7
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDX2 caudal type homeobox 2
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
COX2
CRYGD crystallin, gamma D
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CXCR4 chemokine (C-X-C motif) receptor 4
DCLK1 doublecortin-like kinase 1
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FOXM1 forkhead box M1
GADD45G growth arrest and DNA-damage-inducible, gamma
GAST gastrin
GCG glucagon
GGNBP2 gametogenetin binding protein 2
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
GREM1 gremlin 1, DAN family BMP antagonist
GSDME gasdermin E
GUCA2A guanylate cyclase activator 2A (guanylin)
HLTF helicase-like transcription factor
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
IL33 interleukin 33
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT15 keratin 15, type I
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MET MET proto-oncogene, receptor tyrosine kinase
MLH1 mutL homolog 1
MMP9 matrix metallopeptidase 9
MSI1 musashi RNA-binding protein 1
MSI2 musashi RNA-binding protein 2
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR5A2 nuclear receptor subfamily 5, group A, member 2
NTN1 netrin 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PDCD1 programmed cell death 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PRDX1 peroxiredoxin 1
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PROX1 prospero homeobox 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAG2 recombination activating gene 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RSPO3 R-spondin 3
SFRP1 secreted frizzled-related protein 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC12A9 solute carrier family 12, member 9
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SMAD4 SMAD family member 4
SMS spermine synthase
SPHK1 sphingosine kinase 1
TCF4 transcription factor 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIGAR TP53 induced glycolysis regulatory phosphatase
TP53 tumor protein p53
USP28 ubiquitin specific peptidase 28
USP9X ubiquitin specific peptidase 9, X-linked
WNT5A wingless-type MMTV integration site family, member 5A
XPA xeroderma pigmentosum, complementation group A