Intestinal Polyposis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description The presence of multiple polyps in the intestine. (Human Phenotype Ontology, HP_0200008)
External Link https://www.disgenet.org/browser/0/1/0/C1257915
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Genes

49 genes associated with the disease Intestinal Polyposis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACVRL1 activin A receptor type II-like 1
APC adenomatous polyposis coli
BMPR1A bone morphogenetic protein receptor, type IA
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CDX2 caudal type homeobox 2
CEP57 centrosomal protein 57kDa
COMP cartilage oligomeric matrix protein
CTBP2 C-terminal binding protein 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUX1 cut-like homeobox 1
CXCR2 chemokine (C-X-C motif) receptor 2
ECE1 endothelin converting enzyme 1
EDN3 endothelin 3
EDNRB endothelin receptor type B
ENG endoglin
EPCAM epithelial cell adhesion molecule
FAN1 FANCD2/FANCI-associated nuclease 1
GAST gastrin
GDF2 growth differentiation factor 2
GDNF glial cell derived neurotrophic factor
GNAS GNAS complex locus
HMGA1 high mobility group AT-hook 1
KLF5 Kruppel-like factor 5 (intestinal)
KRAS Kirsten rat sarcoma viral oncogene homolog
MLH1 mutL homolog 1
MLH3 mutL homolog 3
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MUTYH mutY homolog
NRTN neurturin
PARP1 poly (ADP-ribose) polymerase 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G10 phospholipase A2, group X
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PTEN phosphatase and tensin homolog
RET ret proto-oncogene
SEC23B Sec23 homolog B (S. cerevisiae)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SMAD4 SMAD family member 4
STK11 serine/threonine kinase 11
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TRIP13 thyroid hormone receptor interactor 13