Intracranial Aneurysm Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0007766
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Genes

279 genes associated with the disease Intracranial Aneurysm in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACSM3 acyl-CoA synthetase medium-chain family member 3
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTB actin, beta
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADCY10 adenylate cyclase 10 (soluble)
ADCY7 adenylate cyclase 7
AGER advanced glycosylation end product-specific receptor
AGMO alkylglycerol monooxygenase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKAP10 A kinase (PRKA) anchor protein 10
ALB albumin
ANGPT1 angiopoietin 1
ANGPTL6 angiopoietin-like 6
ANKRD44 ankyrin repeat domain 44
ANXA3 annexin A3
AOC3 amine oxidase, copper containing 3
APC adenomatous polyposis coli
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOB apolipoprotein B
APOC2 apolipoprotein C-II
APOE apolipoprotein E
ARHGAP32 Rho GTPase activating protein 32
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATG14 autophagy related 14
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BIRC2 baculoviral IAP repeat containing 2
BLM Bloom syndrome, RecQ helicase-like
BOLL boule-like RNA-binding protein
C3AR1 complement component 3a receptor 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CARD11 caspase recruitment domain family, member 11
CARD8 caspase recruitment domain family, member 8
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBR1 carbonyl reductase 1
CBS cystathionine-beta-synthase
CCDC80 coiled-coil domain containing 80
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CD14 CD14 molecule
CD163L1 CD163 molecule-like 1
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CFD complement factor D (adipsin)
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COL1A2 collagen, type I, alpha 2
COL22A1 collagen, type XXII, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
COX2
CST3 cystatin C
CTNND1 catenin (cadherin-associated protein), delta 1
CTSB cathepsin B
CTSK cathepsin K
CTSS cathepsin S
CXCL12 chemokine (C-X-C motif) ligand 12
CYBA cytochrome b-245, alpha polypeptide
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DHFR dihydrofolate reductase
DPP4 dipeptidyl-peptidase 4
DRAM1 DNA-damage regulated autophagy modulator 1
DSCAM Down syndrome cell adhesion molecule
E2F4 E2F transcription factor 4, p107/p130-binding
EDN1 endothelin 1
EDNRA endothelin receptor type A
ELN elastin
ENG endoglin
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FBN1 fibrillin 1
FBN2 fibrillin 2
FERD3L Fer3-like bHLH transcription factor
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FHIT fragile histidine triad
FLNA filamin A, alpha
FMO4 flavin containing monooxygenase 4
FN1 fibronectin 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBA glucosidase, beta, acid
GDE1 glycerophosphodiester phosphodiesterase 1
GORASP1 golgi reassembly stacking protein 1, 65kDa
GREM1 gremlin 1, DAN family BMP antagonist
GSTO1 glutathione S-transferase omega 1
GYPA glycophorin A (MNS blood group)
GYPB glycophorin B (MNS blood group)
GYPE glycophorin E (MNS blood group)
HAVCR2 hepatitis A virus cellular receptor 2
HCCS holocytochrome c synthase
HDAC9 histone deacetylase 9
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H3A histone cluster 1, H3a
HIST1H3B histone cluster 1, H3b
HIST1H3C histone cluster 1, H3c
HIST1H3D histone cluster 1, H3d
HIST1H3E histone cluster 1, H3e
HIST1H3F histone cluster 1, H3f
HIST1H3G histone cluster 1, H3g
HIST1H3H histone cluster 1, H3h
HIST1H3I histone cluster 1, H3i
HIST1H3J histone cluster 1, H3j
HLA-A major histocompatibility complex, class I, A
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPN hepsin
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPG2 heparan sulfate proteoglycan 2
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IARS1 isoleucyl-tRNA synthetase 1
IFNG interferon, gamma
IFT88 intraflagellar transport 88
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL2RG interleukin 2 receptor, gamma
IL6 interleukin 6
INTS4 integrator complex subunit 4
IQSEC1 IQ motif and Sec7 domain 1
IRS2 insulin receptor substrate 2
JDP2 Jun dimerization protein 2
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDR kinase insert domain receptor
KLF2 Kruppel-like factor 2
KLF5 Kruppel-like factor 5 (intestinal)
KLK4 kallikrein-related peptidase 4
LBR lamin B receptor
LDLR low density lipoprotein receptor
LGALS9 lectin, galactoside-binding, soluble, 9
LIFR leukemia inhibitory factor receptor alpha
LIMK1 LIM domain kinase 1
LINGO2 leucine rich repeat and Ig domain containing 2
LMOD1 leiomodin 1 (smooth muscle)
LOC102724560 cystathionine beta-synthase
LOX lysyl oxidase
LOXL1 lysyl oxidase-like 1
LOXL2 lysyl oxidase-like 2
LOXL3 lysyl oxidase-like 3
LOXL4 lysyl oxidase-like 4
LPA lipoprotein, Lp(a)
LRRC3 leucine rich repeat containing 3
LTBP4 latent transforming growth factor beta binding protein 4
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MCL1 myeloid cell leukemia 1
MET MET proto-oncogene, receptor tyrosine kinase
MINK1 misshapen-like kinase 1
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUC3B mucin 3B, cell surface associated
MYEOV myeloma overexpressed
MYH11 myosin, heavy chain 11, smooth muscle
MYLK myosin light chain kinase
MYO3B myosin IIIB
MYOCD myocardin
NCF1 neutrophil cytosolic factor 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NIFK nucleolar protein interacting with the FHA domain of MKI67
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
NT5C3A 5'-nucleotidase, cytosolic IIIA
NTM neurotrimin
OCA2 oculocutaneous albinism II
OLFML2A olfactomedin-like 2A
PARP1 poly (ADP-ribose) polymerase 1
PCNT pericentrin
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDGFD platelet derived growth factor D
PDLIM5 PDZ and LIM domain 5
PEA15 phosphoprotein enriched in astrocytes 15
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLAT plasminogen activator, tissue
PLG plasminogen
PRDM2 PR domain containing 2, with ZNF domain
PRDM6 PR domain containing 6
PRDM9 PR domain containing 9
PROM1 prominin 1
PSG5 pregnancy specific beta-1-glycoprotein 5
PTEN phosphatase and tensin homolog
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGFR prostaglandin F receptor (FP)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRD protein tyrosine phosphatase, receptor type, D
RBBP8 retinoblastoma binding protein 8
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RNF144A ring finger protein 144A
RNF213 ring finger protein 213
RP1 retinitis pigmentosa 1 (autosomal dominant)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAGE1 sarcoma antigen 1
SCARF1 scavenger receptor class F, member 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SELE selectin E
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETD2 SET domain containing 2
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14
SLC35F3 solute carrier family 35, member F3
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SOX17 SRY (sex determining region Y)-box 17
SRPK1 SRSF protein kinase 1
STARD13 StAR-related lipid transfer (START) domain containing 13
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
SUSD1 sushi domain containing 1
SYT1 synaptotagmin I
TCF12 transcription factor 12
TCF24 transcription factor 24
TCN2 transcobalamin II
TGFB1 transforming growth factor, beta 1
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
THSD1 thrombospondin, type I, domain containing 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TM7SF2 transmembrane 7 superfamily member 2
TMEM132B transmembrane protein 132B
TMOD1 tropomodulin 1
TNF tumor necrosis factor
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOX thymocyte selection-associated high mobility group box
TSC1 tuberous sclerosis 1
TWIST1 twist family bHLH transcription factor 1
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative)
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIP vasoactive intestinal peptide
VSIG4 V-set and immunoglobulin domain containing 4
WDR48 WD repeat domain 48
WNK1 WNK lysine deficient protein kinase 1
WNT3 wingless-type MMTV integration site family, member 3
WWOX WW domain containing oxidoreductase
ZNF365 zinc finger protein 365