Intraepithelial Neoplasia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0878500
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Genes

176 genes associated with the disease Intraepithelial Neoplasia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AMER1 APC membrane recruitment protein 1
APC adenomatous polyposis coli
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
AREG amphiregulin
ARHGAP24 Rho GTPase activating protein 24
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BHLHA15 basic helix-loop-helix family, member a15
BHLHE40 basic helix-loop-helix family, member e40
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C17ORF97 chromosome 17 open reading frame 97
CCND1 cyclin D1
CCND2 cyclin D2
CD163 CD163 molecule
CD274 CD274 molecule
CD33 CD33 molecule
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CD68 CD68 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CENPH centromere protein H
CFL1 cofilin 1 (non-muscle)
CLDN1 claudin 1
CLDN18 claudin 18
CLDN7 claudin 7
COMMD3-BMI1 COMMD3-BMI1 readthrough
COX2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
DCTN6 dynactin 6
DPH1 diphthamide biosynthesis 1
DUOX1 dual oxidase 1
DUSP4 dual specificity phosphatase 4
EGFR epidermal growth factor receptor
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPCAM epithelial cell adhesion molecule
EPHA1 EPH receptor A1
ERBB2 erb-b2 receptor tyrosine kinase 2
EREG epiregulin
ESR1 estrogen receptor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F11R F11 receptor
FAM3C family with sequence similarity 3, member C
FGF8 fibroblast growth factor 8 (androgen-induced)
FN1 fibronectin 1
FOXO3 forkhead box O3
FOXP1 forkhead box P1
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GATA3 GATA binding protein 3
GLS glutaminase
GORASP1 golgi reassembly stacking protein 1, 65kDa
GSTP1 glutathione S-transferase pi 1
H2AX H2A.X variant histone
HES1 hes family bHLH transcription factor 1
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
HSPG2 heparan sulfate proteoglycan 2
IFI27 interferon, alpha-inducible protein 27
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IP6K1 inositol hexakisphosphate kinase 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KDM6B lysine (K)-specific demethylase 6B
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT13 keratin 13, type I
KRT16 keratin 16, type I
KRT19 keratin 19, type I
KRT20 keratin 20, type I
KRT4 keratin 4, type II
LAMC2 laminin, gamma 2
LATS1 large tumor suppressor kinase 1
LDHB lactate dehydrogenase B
LGALS7 lectin, galactoside-binding, soluble, 7
LGALS7B lectin, galactoside-binding, soluble, 7B
LMO4 LIM domain only 4
LPAR2 lysophosphatidic acid receptor 2
MAPK8 mitogen-activated protein kinase 8
MCM2 minichromosome maintenance complex component 2
MCM7 minichromosome maintenance complex component 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEN1 multiple endocrine neoplasia I
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP20 matrix metallopeptidase 20
MMP25 matrix metallopeptidase 25
MMP7 matrix metallopeptidase 7
MRPL28 mitochondrial ribosomal protein L28
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
NFE2L2 nuclear factor, erythroid 2-like 2
NGFR nerve growth factor receptor
NOTCH1 notch 1
NXT1 nuclear transport factor 2-like export factor 1
PDCD1 programmed cell death 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDHX pyruvate dehydrogenase complex, component X
PDLIM7 PDZ and LIM domain 7 (enigma)
PDPN podoplanin
PDX1 pancreatic and duodenal homeobox 1
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKM pyruvate kinase, muscle
PLAU plasminogen activator, urokinase
PLG plasminogen
PMEL premelanosome protein
POU5F1 POU class 5 homeobox 1
PRL prolactin
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PYCARD PYD and CARD domain containing
RACK1 receptor for activated C kinase 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RIPK2 receptor-interacting serine-threonine kinase 2
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RUNX3 runt-related transcription factor 3
S100A1 S100 calcium binding protein A1
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMAD4 SMAD family member 4
SOCS1 suppressor of cytokine signaling 1
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SPINK1 serine peptidase inhibitor, Kazal type 1
SPP1 secreted phosphoprotein 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STIL SCL/TAL1 interrupting locus
STS steroid sulfatase (microsomal), isozyme S
SUB1 SUB1 homolog (S. cerevisiae)
SUMO1 small ubiquitin-like modifier 1
SYT1 synaptotagmin I
TFF1 trefoil factor 1
TGFB1 transforming growth factor, beta 1
TGM3 transglutaminase 3
TICAM2 toll-like receptor adaptor molecule 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TNC tenascin C
TP53 tumor protein p53
TP73 tumor protein p73
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VSIR V-set immunoregulatory receptor
VTN vitronectin
WNK1 WNK lysine deficient protein kinase 1
ZIC1 Zic family member 1