Intrinsic Asthma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An asthma that is triggered by factors not related to allergies such as anxiety, stress, exercise, cold air, dry air, hyperventilation, smoke, viruses, chemical irritants, autonomic imbalance, hormonal deficiencies and psychogenic influences. It is characterized by airway obstruction and inflammation that is at least partially reversible with medication. The symptoms include coughing, wheezing, shortness of breath or rapid breathing, and chest tightness. (Human Disease Ontology, DOID_9360)
External Link https://www.disgenet.org/browser/0/1/0/C0155880
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Genes

29 genes associated with the disease Intrinsic Asthma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
CAT catalase
CD200 CD200 molecule
CD48 CD48 molecule
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DPP4 dipeptidyl-peptidase 4
GRIK2 glutamate receptor, ionotropic, kainate 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IL10 interleukin 10
IL13 interleukin 13
IL3 interleukin 3
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6R interleukin 6 receptor
NTS neurotensin
RBM45 RNA binding motif protein 45
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
STATH statherin
TBX21 T-box 21