Invasive Carcinoma Of Breast Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0853879
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Genes

449 genes associated with the disease Invasive Carcinoma Of Breast in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
ACE angiotensin I converting enzyme
ACSS2 acyl-CoA synthetase short-chain family member 2
ACTB actin, beta
ADGRE2 adhesion G protein-coupled receptor E2
ADM adrenomedullin
AFAP1L2 actin filament associated protein 1-like 2
AGO2 argonaute RISC catalytic component 2
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALB albumin
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX5 arachidonate 5-lipoxygenase
ANKRD30A ankyrin repeat domain 30A
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APP amyloid beta (A4) precursor protein
AR androgen receptor
AREG amphiregulin
ARF6 ADP-ribosylation factor 6
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP18 Rho GTPase activating protein 18
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARID1A AT rich interactive domain 1A (SWI-like)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
AVP arginine vasopressin
AZIN2 antizyme inhibitor 2
BAG1 BCL2-associated athanogene
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BBC3 BCL2 binding component 3
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BECN1 beclin 1, autophagy related
BHLHE22 basic helix-loop-helix family, member e22
BLID BH3-like motif containing, cell death inducer
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRD4 bromodomain containing 4
BRMS1 breast cancer metastasis suppressor 1
BSG basigin (Ok blood group)
BST2 bone marrow stromal cell antigen 2
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C6ORF106 chromosome 6 open reading frame 106
CA9 carbonic anhydrase IX
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CBX2 chromobox homolog 2
CCL1 chemokine (C-C motif) ligand 1
CCL22 chemokine (C-C motif) ligand 22
CCN1 cellular communication network factor 1
CCN2 cellular communication network factor 2
CCNA2 cyclin A2
CCND1 cyclin D1
CD163 CD163 molecule
CD1A CD1a molecule
CD24 CD24 molecule
CD274 CD274 molecule
CD44 CD44 molecule (Indian blood group)
CD47 CD47 molecule
CD68 CD68 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD9 CD9 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK1 cyclin-dependent kinase 1
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEMIP cell migration inducing protein, hyaluronan binding
CERS6 ceramide synthase 6
CHEK1 checkpoint kinase 1
CHI3L2 chitinase 3-like 2
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CIB1 calcium and integrin binding 1 (calmyrin)
CKAP4 cytoskeleton-associated protein 4
CLDN1 claudin 1
CLDN3 claudin 3
CLDN7 claudin 7
CNTN3 contactin 3 (plasmacytoma associated)
COL18A1 collagen, type XVIII, alpha 1
COMT catechol-O-methyltransferase
COPS5 COP9 signalosome subunit 5
COX2
CRP C-reactive protein, pentraxin-related
CST6 cystatin E/M
CSTA cystatin A (stefin A)
CTCF CCCTC-binding factor (zinc finger protein)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSA cathepsin A
CTSD cathepsin D
CTSS cathepsin S
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DACH1 dachshund family transcription factor 1
DAP death-associated protein
DCTN6 dynactin 6
DGCR8 DGCR8 microprocessor complex subunit
DHCR24 24-dehydrocholesterol reductase
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNM1L dynamin 1-like
DPYD dihydropyrimidine dehydrogenase
ECT2 epithelial cell transforming 2
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELANE elastase, neutrophil expressed
ELP3 elongator acetyltransferase complex subunit 3
EPCAM epithelial cell adhesion molecule
EPHA2 EPH receptor A2
EPHB4 EPH receptor B4
EPHB6 EPH receptor B6
EPO erythropoietin
EPOR erythropoietin receptor
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV6 ets variant 6
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F11R F11 receptor
F2R coagulation factor II (thrombin) receptor
F2RL2 coagulation factor II (thrombin) receptor-like 2
FABP7 fatty acid binding protein 7, brain
FANCD2 Fanconi anemia, complementation group D2
FANCF Fanconi anemia, complementation group F
FAS Fas cell surface death receptor
FASN fatty acid synthase
FAT1 FAT atypical cadherin 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FDXR ferredoxin reductase
FERMT2 fermitin family member 2
FEV FEV (ETS oncogene family)
FGF3 fibroblast growth factor 3
FGFBP1 fibroblast growth factor binding protein 1
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FHIT fragile histidine triad
FKBP1A FK506 binding protein 1A, 12kDa
FLT1 fms-related tyrosine kinase 1
FN1 fibronectin 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXA1 forkhead box A1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FOXQ1 forkhead box Q1
FPR2 formyl peptide receptor 2
FSHR follicle stimulating hormone receptor
FST follistatin
FSTL3 follistatin-like 3 (secreted glycoprotein)
FZD1 frizzled class receptor 1
G0S2 G0/G1 switch 2
GADL1 glutamate decarboxylase-like 1
GATA3 GATA binding protein 3
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GMNN geminin, DNA replication inhibitor
GNAS GNAS complex locus
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GPER1 G protein-coupled estrogen receptor 1
GPI glucose-6-phosphate isomerase
GRB7 growth factor receptor-bound protein 7
GREB1 growth regulation by estrogen in breast cancer 1
GSN gelsolin
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HACD1 3-hydroxyacyl-CoA dehydratase 1
HAS2 hyaluronan synthase 2
HBP1 HMG-box transcription factor 1
HDAC1 histone deacetylase 1
HDAC6 histone deacetylase 6
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HPGDS hematopoietic prostaglandin D synthase
HPSE heparanase
HRG histidine-rich glycoprotein
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFI27 interferon, alpha-inducible protein 27
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL13RA1 interleukin 13 receptor, alpha 1
IL13RA2 interleukin 13 receptor, alpha 2
IL17A interleukin 17A
IL6 interleukin 6
INSR insulin receptor
INTS2 integrator complex subunit 2
IRF1 interferon regulatory factor 1
IRF5 interferon regulatory factor 5
ITFG1 integrin alpha FG-GAP repeat containing 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KANK1 KN motif and ankyrin repeat domains 1
KDM6B lysine (K)-specific demethylase 6B
KDR kinase insert domain receptor
KEAP1 kelch-like ECH-associated protein 1
KIAA1804 mixed lineage kinase 4
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLK6 kallikrein-related peptidase 6
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KMT2D lysine (K)-specific methyltransferase 2D
KRT14 keratin 14, type I
KRT19 keratin 19, type I
LCN2 lipocalin 2
LDHB lactate dehydrogenase B
LEP leptin
LEPR leptin receptor
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LMNA lamin A/C
LNPEP leucyl/cystinyl aminopeptidase
LOX lysyl oxidase
LPAR1 lysophosphatidic acid receptor 1
LUM lumican
MAGEA3 melanoma antigen family A3
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAPK14 mitogen-activated protein kinase 14
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MB myoglobin
MCM2 minichromosome maintenance complex component 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEST mesoderm specific transcript
MET MET proto-oncogene, receptor tyrosine kinase
MMP1 matrix metallopeptidase 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MRC1 mannose receptor, C type 1
MRPL28 mitochondrial ribosomal protein L28
MSH3 mutS homolog 3
MTDH metadherin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTUS1 microtubule associated tumor suppressor 1
MUC1 mucin 1, cell surface associated
MUC4 mucin 4, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCBPAP MYCBP associated protein
NCOR1 nuclear receptor corepressor 1
NCSTN nicastrin
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NLRP1 NLR family, pyrin domain containing 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOP14 NOP14 nucleolar protein
NOS3 nitric oxide synthase 3 (endothelial cell)
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRF1 nuclear respiratory factor 1
NUSAP1 nucleolar and spindle associated protein 1
NXT1 nuclear transport factor 2-like export factor 1
OLFM4 olfactomedin 4
OSM oncostatin M
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PALB2 partner and localizer of BRCA2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARD3 par-3 family cell polarity regulator
PAX6 paired box 6
PBRM1 polybromo 1
PC pyruvate carboxylase
PDGFC platelet derived growth factor C
PELP1 proline, glutamate and leucine rich protein 1
PGR progesterone receptor
PI3 peptidase inhibitor 3, skin-derived
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIP prolactin-induced protein
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLA2G15 phospholipase A2, group XV
PLAU plasminogen activator, urokinase
PLCB2 phospholipase C, beta 2
PLD2 phospholipase D2
PLG plasminogen
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PON1 paraoxonase 1
POSTN periostin, osteoblast specific factor
POTEF POTE ankyrin domain family, member F
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRIMPOL primase and polymerase (DNA-directed)
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD3 protein kinase D3
PROM1 prominin 1
PRPF38B pre-mRNA processing factor 38B
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTTG1 pituitary tumor-transforming 1
PUM1 pumilio RNA-binding family member 1
PXN paxillin
PYGM phosphorylase, glycogen, muscle
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAP1GAP RAP1 GTPase activating protein
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
RARB retinoic acid receptor, beta
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM15B RNA binding motif protein 15B
RBM3 RNA binding motif (RNP1, RRM) protein 3
RECK reversion-inducing-cysteine-rich protein with kazal motifs
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RET ret proto-oncogene
RNF126 ring finger protein 126
RPE65 retinal pigment epithelium-specific protein 65kDa
RPS6 ribosomal protein S6
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX2 runt-related transcription factor 2
RUVBL1 RuvB-like AAA ATPase 1
RXRG retinoid X receptor, gamma
S100A4 S100 calcium binding protein A4
S100A7 S100 calcium binding protein A7
S1PR2 sphingosine-1-phosphate receptor 2
SCO2 SCO2 cytochrome c oxidase assembly protein
SDC1 syndecan 1
SELE selectin E
SEPT2 septin 2
SEPT6 septin 6
SEPT7 septin 7
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETD1A SET domain containing 1A
SETD2 SET domain containing 2
SFRP1 secreted frizzled-related protein 1
SH3BP4 SH3-domain binding protein 4
SIM2 single-minded family bHLH transcription factor 2
SIPA1 signal-induced proliferation-associated 1
SLC12A9 solute carrier family 12, member 9
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLIT2 slit homolog 2 (Drosophila)
SLN sarcolipin
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
SMR3B submaxillary gland androgen regulated protein 3B
SNAI1 snail family zinc finger 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNX27 sorting nexin family member 27
SORBS1 sorbin and SH3 domain containing 1
SOX11 SRY (sex determining region Y)-box 11
SOX2 SRY (sex determining region Y)-box 2
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPDEF SAM pointed domain containing ETS transcription factor
SPHK1 sphingosine kinase 1
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUB1 SUB1 homolog (S. cerevisiae)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBPL1 TBP-like 1
TBX3 T-box 3
TFPI2 tissue factor pathway inhibitor 2
TFRC transferrin receptor
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
THBS2 thrombospondin 2
THRB thyroid hormone receptor, beta
THRSP thyroid hormone responsive
TICAM2 toll-like receptor adaptor molecule 2
TIMP1 TIMP metallopeptidase inhibitor 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMPRSS2 transmembrane protease, serine 2
TNC tenascin C
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOMM34 translocase of outer mitochondrial membrane 34
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP63 tumor protein p63
TRIM27 tripartite motif containing 27
TRIM29 tripartite motif containing 29
TRIM62 tripartite motif containing 62
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TWIST1 twist family bHLH transcription factor 1
TYMP thymidine phosphorylase
TYMS thymidylate synthetase
TYRP1 tyrosinase-related protein 1
UBQLN1 ubiquilin 1
USP19 ubiquitin specific peptidase 19
UVRAG UV radiation resistance associated
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VRK1 vaccinia related kinase 1
WBP2NL WBP2 N-terminal like
WNT5A wingless-type MMTV integration site family, member 5A
WWOX WW domain containing oxidoreductase
XK X-linked Kx blood group
XPO1 exportin 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YAP1 Yes-associated protein 1
ZFP36 ZFP36 ring finger protein
ZIC1 Zic family member 1
ZNF469 zinc finger protein 469