Invasive Ductal Breast Carcinoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1134719
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Genes

391 genes associated with the disease Invasive Ductal Breast Carcinoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACKR3 atypical chemokine receptor 3
ACTB actin, beta
ACTN4 actinin, alpha 4
ACVR1C activin A receptor, type IC
ADAM12 ADAM metallopeptidase domain 12
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
AGR3 anterior gradient 3
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA6 annexin A6
APC adenomatous polyposis coli
APOA1 apolipoprotein A-I
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOC1 apolipoprotein C-I
AQP4 aquaporin 4
AQP5 aquaporin 5
AR androgen receptor
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARID1A AT rich interactive domain 1A (SWI-like)
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATF4 activating transcription factor 4
ATM ATM serine/threonine kinase
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
AURKA aurora kinase A
BAG1 BCL2-associated athanogene
BCL2 B-cell CLL/lymphoma 2
BECN1 beclin 1, autophagy related
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRD8 bromodomain containing 8
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C6ORF106 chromosome 6 open reading frame 106
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBX7 chromobox homolog 7
CCL2 chemokine (C-C motif) ligand 2
CCL27 chemokine (C-C motif) ligand 27
CCN1 cellular communication network factor 1
CCND1 cyclin D1
CCND2 cyclin D2
CD14 CD14 molecule
CD163 CD163 molecule
CD1A CD1a molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CD68 CD68 molecule
CD82 CD82 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH22 cadherin 22, type 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2
CHD1L chromodomain helicase DNA binding protein 1-like
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHUK conserved helix-loop-helix ubiquitous kinase
CKAP4 cytoskeleton-associated protein 4
CLDN4 claudin 4
CLDN7 claudin 7
CMA1 chymase 1, mast cell
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNTROB centrobin, centrosomal BRCA2 interacting protein
COL4A1 collagen, type IV, alpha 1
COL5A1 collagen, type V, alpha 1
COX2
COX5B cytochrome c oxidase subunit Vb
CRABP2 cellular retinoic acid binding protein 2
CST6 cystatin E/M
CSTA cystatin A (stefin A)
CTBP1 C-terminal binding protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CTHRC1 collagen triple helix repeat containing 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTSD cathepsin D
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DCN decorin
DCTN4 dynactin 4 (p62)
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DGCR8 DGCR8 microprocessor complex subunit
DHCR24 24-dehydrocholesterol reductase
DHRS11 dehydrogenase/reductase (SDR family) member 11
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DPEP1 dipeptidase 1 (renal)
EGFL7 EGF-like-domain, multiple 7
EGFR epidermal growth factor receptor
EGLN2 egl-9 family hypoxia-inducible factor 2
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF4E eukaryotic translation initiation factor 4E
ELP3 elongator acetyltransferase complex subunit 3
ENO1 enolase 1, (alpha)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESYT1 extended synaptotagmin-like protein 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBL fibrillarin
FBXO39 F-box protein 39
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR4 fibroblast growth factor receptor 4
FHIT fragile histidine triad
FMO2 flavin containing monooxygenase 2 (non-functional)
FN1 fibronectin 1
FOXF1 forkhead box F1
FOXM1 forkhead box M1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FST follistatin
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GAL3ST1 galactose-3-O-sulfotransferase 1
GATA3 GATA binding protein 3
GATAD2B GATA zinc finger domain containing 2B
GDF10 growth differentiation factor 10
GJB2 gap junction protein, beta 2, 26kDa
GLI1 GLI family zinc finger 1
GLI2 GLI family zinc finger 2
GPER1 G protein-coupled estrogen receptor 1
GPX3 glutathione peroxidase 3
GPX4 glutathione peroxidase 4
GRK2 G protein-coupled receptor kinase 2
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
HAVCR2 hepatitis A virus cellular receptor 2
HDAC3 histone deacetylase 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIC1 hypermethylated in cancer 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HOXD10 homeobox D10
HPGDS hematopoietic prostaglandin D synthase
HPSE heparanase
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPE1 heat shock 10kDa protein 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IGF1R insulin-like growth factor 1 receptor
IGSF1 immunoglobulin superfamily, member 1
IL17A interleukin 17A
IL1B interleukin 1, beta
INSIG2 insulin induced gene 2
IRF1 interferon regulatory factor 1
IRF5 interferon regulatory factor 5
IRS1 insulin receptor substrate 1
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
JAG1 jagged 1
KDM2A lysine (K)-specific demethylase 2A
KDM5B lysine (K)-specific demethylase 5B
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KL klotho
KLB klotho beta
KLK10 kallikrein-related peptidase 10
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT8 keratin 8, type II
LAG3 lymphocyte-activation gene 3
LCN2 lipocalin 2
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LIN28B lin-28 homolog B (C. elegans)
LMLN leishmanolysin-like (metallopeptidase M8 family)
LMNA lamin A/C
LMO4 LIM domain only 4
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC102724971 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8
LOC105371045 uncharacterized LOC105371045
LOX lysyl oxidase
LPAR2 lysophosphatidic acid receptor 2
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAOA monoamine oxidase A
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAPK8 mitogen-activated protein kinase 8
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MCAM melanoma cell adhesion molecule
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MCPH1 microcephalin 1
MCTS1 malignant T cell amplified sequence 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGMT O-6-methylguanine-DNA methyltransferase
MKI67 marker of proliferation Ki-67
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP11 matrix metallopeptidase 11
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MMRN1 multimerin 1
MPL MPL proto-oncogene, thrombopoietin receptor
MRC2 mannose receptor, C type 2
MSH2 mutS homolog 2
MSMB microseminoprotein, beta-
MSR1 macrophage scavenger receptor 1
MST1 macrophage stimulating 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MTA1 metastasis associated 1
MUC1 mucin 1, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYLK myosin light chain kinase
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
NAMPT nicotinamide phosphoribosyltransferase
NCOA4 nuclear receptor coactivator 4
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NEK2 NIMA-related kinase 2
NES nestin
NEU1 sialidase 1 (lysosomal sialidase)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NKD1 naked cuticle homolog 1 (Drosophila)
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
NOP2 NOP2 nucleolar protein
NOP53 NOP53 ribosome biogenesis factor
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NR5A2 nuclear receptor subfamily 5, group A, member 2
NSD3 nuclear receptor binding SET domain protein 3
NSUN5 NOP2/Sun domain family, member 5
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUP62 nucleoporin 62kDa
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
OSM oncostatin M
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PCDH10 protocadherin 10
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFB platelet-derived growth factor beta polypeptide
PDPN podoplanin
PECAM1 platelet/endothelial cell adhesion molecule 1
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLAU plasminogen activator, urokinase
PLCB2 phospholipase C, beta 2
PNPO pyridoxamine 5'-phosphate oxidase
POFUT1 protein O-fucosyltransferase 1
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POSTN periostin, osteoblast specific factor
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRLR prolactin receptor
PROCR protein C receptor, endothelial
PRPF38B pre-mRNA processing factor 38B
PRRT2 proline-rich transmembrane protein 2
PRSS3 protease, serine, 3
PSIP1 PC4 and SFRS1 interacting protein 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH1R parathyroid hormone 1 receptor
PTHLH parathyroid hormone-like hormone
PTK6 protein tyrosine kinase 6
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTTG1 pituitary tumor-transforming 1
RAB25 RAB25, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD51 RAD51 recombinase
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RB1 retinoblastoma 1
RB1CC1 RB1-inducible coiled-coil 1
RBM39 RNA binding motif protein 39
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RGN regucalcin
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHOBTB2 Rho-related BTB domain containing 2
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPE65 retinal pigment epithelium-specific protein 65kDa
RPL17 ribosomal protein L17
RPL17-C18ORF32 RPL17-C18orf32 readthrough
RUNX3 runt-related transcription factor 3
S100A6 S100 calcium binding protein A6
SAT2 spermidine/spermine N1-acetyltransferase family member 2
SATB1 SATB homeobox 1
SEC62 SEC62 homolog (S. cerevisiae)
SELE selectin E
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIM2 single-minded family bHLH transcription factor 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC12A9 solute carrier family 12, member 9
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLIT2 slit homolog 2 (Drosophila)
SMAD4 SMAD family member 4
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMR3A submaxillary gland androgen regulated protein 3A
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOD2 superoxide dismutase 2, mitochondrial
SOX18 SRY (sex determining region Y)-box 18
SPA17 sperm autoantigenic protein 17
SPATA2 spermatogenesis associated 2
SPHK1 sphingosine kinase 1
SPP1 secreted phosphoprotein 1
SQSTM1 sequestosome 1
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
SULF2 sulfatase 2
SYK spleen tyrosine kinase
TACC2 transforming, acidic coiled-coil containing protein 2
TACSTD2 tumor-associated calcium signal transducer 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCHP trichoplein, keratin filament binding
TES testin LIM domain protein
TET1 tet methylcytosine dioxygenase 1
TET2 tet methylcytosine dioxygenase 2
TFF1 trefoil factor 1
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
THRA thyroid hormone receptor, alpha
TIAM1 T-cell lymphoma invasion and metastasis 1
TIGIT T cell immunoreceptor with Ig and ITIM domains
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TIPE3 TNF alpha induced protein 8 like 3
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMPRSS13 transmembrane protease, serine 13
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF12-TNFSF13 TNFSF12-TNFSF13 readthrough
TP53 tumor protein p53
TP63 tumor protein p63
TPM4 tropomyosin 4
TRA T cell receptor alpha locus
TWIST1 twist family bHLH transcription factor 1
TYRO3 TYRO3 protein tyrosine kinase
UGCG UDP-glucose ceramide glucosyltransferase
USP28 ubiquitin specific peptidase 28
UVRAG UV radiation resistance associated
VASP vasodilator-stimulated phosphoprotein
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
VWF von Willebrand factor
WDR1 WD repeat domain 1
WNT1 wingless-type MMTV integration site family, member 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZEB1 zinc finger E-box binding homeobox 1