| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ipatasertib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ipatasertib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0614997 |
| TLE4 | transducin-like enhancer of split 4 | 0.0586235 |
| LPIN1 | lipin 1 | 0.0525141 |
| DST | dystonin | 0.0407504 |
| BPTF | bromodomain PHD finger transcription factor | 0.0407142 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0390108 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0368939 |
| PCDH9 | protocadherin 9 | 0.0346317 |
| HMBOX1 | homeobox containing 1 | 0.0346226 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0341336 |
| TRIB2 | tribbles pseudokinase 2 | 0.0333642 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.032206 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0294283 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0291527 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.029148 |
| SYT1 | synaptotagmin I | 0.0276268 |
| ANGPT1 | angiopoietin 1 | 0.0272161 |
| HSPA8 | heat shock 70kDa protein 8 | 0.026261 |
| ENAH | enabled homolog (Drosophila) | 0.0260845 |
| PRKCA | protein kinase C, alpha | 0.0258471 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0255746 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0253232 |
| ZNF292 | zinc finger protein 292 | 0.0250635 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0249073 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0238369 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0230535 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0230381 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0219209 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0218741 |
| AUTS2 | autism susceptibility candidate 2 | 0.0216 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0213983 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0213612 |
| DISP1 | dispatched homolog 1 (Drosophila) | 0.0212175 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0211057 |
| NCOR2 | nuclear receptor corepressor 2 | 0.020933 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0206126 |
| CDK19 | cyclin-dependent kinase 19 | 0.0205009 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0202894 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0201778 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.0201514 |
| TNRC6C | trinucleotide repeat containing 6C | 0.0201118 |
| AOPEP | aminopeptidase O (putative) | 0.0200694 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0200188 |
| OGA | O-GlcNAcase | 0.0200133 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0199669 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0199604 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.019681 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0195873 |
| ANK2 | ankyrin 2, neuronal | 0.0195582 |
| SLMAP | sarcolemma associated protein | 0.0194927 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.019436 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0194352 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0193244 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0190257 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0190147 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.018925 |
| GLCCI1 | glucocorticoid induced 1 | 0.0185979 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0184089 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0182823 |
| MRTFA | myocardin related transcription factor A | 0.0181813 |
| PCDH7 | protocadherin 7 | 0.0176338 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0175611 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0173552 |
| TBX2 | T-box 2 | 0.0171613 |
| PCM1 | pericentriolar material 1 | 0.0170924 |
| AEBP2 | AE binding protein 2 | 0.0169454 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0169101 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0167573 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0166804 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.016532 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0162543 |
| SYNPO2 | synaptopodin 2 | 0.0162165 |
| RPS8 | ribosomal protein S8 | 0.0161624 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0160726 |
| PRKD1 | protein kinase D1 | 0.0160488 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0159756 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0158769 |
| ATOSA | atos homolog A | 0.0157941 |
| FHL2 | four and a half LIM domains 2 | 0.0156161 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.015465 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0154016 |
| EXOC6B | exocyst complex component 6B | 0.0153918 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0153209 |
| ZNF644 | zinc finger protein 644 | 0.0153163 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0151994 |
| RET | ret proto-oncogene | 0.0151039 |
| RORA | RAR-related orphan receptor A | 0.0149298 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0149174 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0148584 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | 0.0148418 |
| JMJD1C | jumonji domain containing 1C | 0.0147349 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0146739 |
| ETV6 | ets variant 6 | 0.0145994 |
| RPL30 | ribosomal protein L30 | 0.0145652 |
| SCFD1 | sec1 family domain containing 1 | 0.0145551 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0145376 |
| MEIS2 | Meis homeobox 2 | 0.0144857 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0144846 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0143228 |
| ZFHX4 | zinc finger homeobox 4 | 0.0142847 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.155071 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.119261 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.109717 |
| IGF2 | insulin-like growth factor 2 | -0.109203 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.105149 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0914732 |
| LSAMP | limbic system-associated membrane protein | -0.0780635 |
| PTMA | prothymosin, alpha | -0.0680319 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0653256 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0616051 |
| NDRG1 | N-myc downstream regulated 1 | -0.061532 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0537117 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0521124 |
| PLAT | plasminogen activator, tissue | -0.0520622 |
| MEF2A | myocyte enhancer factor 2A | -0.0500913 |
| VIM | vimentin | -0.049377 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0447412 |
| MSI2 | musashi RNA-binding protein 2 | -0.0446666 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0440361 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.043182 |
| COL1A1 | collagen, type I, alpha 1 | -0.0430815 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0418142 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0416887 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0409201 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0401548 |
| IER3 | immediate early response 3 | -0.0400165 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.039733 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0396583 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0395691 |
| FN1 | fibronectin 1 | -0.0392952 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0371612 |
| MX2 | MX dynamin-like GTPase 2 | -0.0364748 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0363823 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0363475 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0355252 |
| CDH13 | cadherin 13 | -0.0346902 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.034112 |
| COPA | coatomer protein complex, subunit alpha | -0.0334201 |
| B2M | beta-2-microglobulin | -0.0333641 |
| RPL35A | ribosomal protein L35a | -0.0330563 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0322644 |
| NREP | neuronal regeneration related protein | -0.0318999 |
| FLT1 | fms-related tyrosine kinase 1 | -0.031879 |
| STC1 | stanniocalcin 1 | -0.0317264 |
| SP100 | SP100 nuclear antigen | -0.0317206 |
| CENPF | centromere protein F, 350/400kDa | -0.0312904 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0306633 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0299793 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0298426 |
| TMSB10 | thymosin beta 10 | -0.0295066 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.029085 |
| CUX1 | cut-like homeobox 1 | -0.028726 |
| HIP1 | huntingtin interacting protein 1 | -0.0286754 |
| H3-3B | H3.3 histone B | -0.0280125 |
| PRRC2C | proline-rich coiled-coil 2C | -0.027845 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0274766 |
| CCDC91 | coiled-coil domain containing 91 | -0.027277 |
| WDR45B | WD repeat domain 45B | -0.026848 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0266679 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0262915 |
| ZNF638 | zinc finger protein 638 | -0.0262458 |
| FAM13A | family with sequence similarity 13, member A | -0.0259919 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0257909 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0257642 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0254176 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0250414 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0247708 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0246926 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0244323 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0241834 |
| CALR | calreticulin | -0.0241424 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0241279 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0240642 |
| GOLGA4 | golgin A4 | -0.0235843 |
| MCL1 | myeloid cell leukemia 1 | -0.0235632 |
| RIGI | RNA sensor RIG-I | -0.0234941 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0234905 |
| RNF213 | ring finger protein 213 | -0.0234596 |
| CANX | calnexin | -0.0234567 |
| FTL | ferritin, light polypeptide | -0.0233929 |
| FHIT | fragile histidine triad | -0.0230756 |
| ARF4 | ADP-ribosylation factor 4 | -0.0226574 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0225192 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0224722 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0223677 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0220939 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0219125 |
| NFIB | nuclear factor I/B | -0.0216629 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0216319 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0213212 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0206313 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0204925 |
| ACTG1 | actin gamma 1 | -0.0202134 |
| TPR | translocated promoter region, nuclear basket protein | -0.0201776 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0201187 |
| RPLP1 | ribosomal protein, large, P1 | -0.0201048 |
| CALD1 | caldesmon 1 | -0.0200582 |
| KIF26A | kinesin family member 26A | -0.0196638 |
| ADM | adrenomedullin | -0.0194597 |
| TPM4 | tropomyosin 4 | -0.0194594 |
