| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ipatasertib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ipatasertib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.170645 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.136893 |
| HDAC9 | histone deacetylase 9 | 0.129544 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.10381 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0908303 |
| MACROD2 | MACRO domain containing 2 | 0.0857766 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0818024 |
| RPS12 | ribosomal protein S12 | 0.0790907 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0746839 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0718591 |
| PDGFC | platelet derived growth factor C | 0.0686603 |
| FOXP1 | forkhead box P1 | 0.0680429 |
| EGFR | epidermal growth factor receptor | 0.0662608 |
| RPS6 | ribosomal protein S6 | 0.063521 |
| RPS8 | ribosomal protein S8 | 0.0625388 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0616926 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0611699 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0601933 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0585751 |
| TJP1 | tight junction protein 1 | 0.0584901 |
| SMYD3 | SET and MYND domain containing 3 | 0.0577339 |
| RPL9 | ribosomal protein L9 | 0.0573893 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0565149 |
| RPL31 | ribosomal protein L31 | 0.054558 |
| RPL5 | ribosomal protein L5 | 0.0529603 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0527921 |
| ZNF608 | zinc finger protein 608 | 0.0521936 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0514403 |
| RPS3 | ribosomal protein S3 | 0.0514173 |
| EFNA5 | ephrin-A5 | 0.0510986 |
| RPL37A | ribosomal protein L37a | 0.050372 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0490296 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.04899 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.046649 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0454805 |
| RPS25 | ribosomal protein S25 | 0.0451013 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0440679 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0432533 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0431896 |
| RPL13A | ribosomal protein L13a | 0.042676 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0425984 |
| NFIA | nuclear factor I/A | 0.0420929 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0413546 |
| PLCE1 | phospholipase C, epsilon 1 | 0.0412447 |
| TXNRD1 | thioredoxin reductase 1 | 0.0408384 |
| ZNF292 | zinc finger protein 292 | 0.0408043 |
| TNPO1 | transportin 1 | 0.0407349 |
| BPTF | bromodomain PHD finger transcription factor | 0.0407238 |
| RPS29 | ribosomal protein S29 | 0.0403923 |
| CLASP2 | cytoplasmic linker associated protein 2 | 0.0401146 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0398311 |
| RAB27B | RAB27B, member RAS oncogene family | 0.039807 |
| TRERF1 | transcriptional regulating factor 1 | 0.0391636 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0388743 |
| LONRF2 | LON peptidase N-terminal domain and ring finger 2 | 0.0382695 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0380638 |
| RPS13 | ribosomal protein S13 | 0.036607 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0350762 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0345756 |
| RPLP2 | ribosomal protein, large, P2 | 0.0341874 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0340526 |
| RPLP1 | ribosomal protein, large, P1 | 0.0340195 |
| RPL36 | ribosomal protein L36 | 0.0338414 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0335801 |
| RTN4 | reticulon 4 | 0.0331154 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0328965 |
| YAP1 | Yes-associated protein 1 | 0.0328944 |
| ANK2 | ankyrin 2, neuronal | 0.0317748 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0317602 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0314229 |
| RPL26 | ribosomal protein L26 | 0.0296801 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0293548 |
| FMN1 | formin 1 | 0.0293107 |
| PYGB | phosphorylase, glycogen; brain | 0.0292722 |
| RBM25 | RNA binding motif protein 25 | 0.028708 |
| OSBPL1A | oxysterol binding protein-like 1A | 0.0283561 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0276979 |
| RPL7A | ribosomal protein L7a | 0.0275274 |
| JMJD1C | jumonji domain containing 1C | 0.0274415 |
| RPS2 | ribosomal protein S2 | 0.0272445 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0272409 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0270663 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0268033 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0263184 |
| SSH2 | slingshot protein phosphatase 2 | 0.0258317 |
| RPL11 | ribosomal protein L11 | 0.025818 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0257593 |
| RPL37 | ribosomal protein L37 | 0.0255264 |
| RPS27 | ribosomal protein S27 | 0.0255017 |
| MED13L | mediator complex subunit 13-like | 0.0254225 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0252523 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0245869 |
| SFTPA2 | surfactant protein A2 | 0.024527 |
| RPL30 | ribosomal protein L30 | 0.0242869 |
| FTL | ferritin, light polypeptide | 0.0242312 |
| PDE10A | phosphodiesterase 10A | 0.0241754 |
| RYK | receptor-like tyrosine kinase | 0.0241276 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0241013 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0240554 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0239632 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.20153 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.164891 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.126207 |
| AHNAK | AHNAK nucleoprotein | -0.11503 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.111001 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.107933 |
| BMP10 | bone morphogenetic protein 10 | -0.107005 |
| TMSB4X | thymosin beta 4, X-linked | -0.0998682 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0799695 |
| MKI67 | marker of proliferation Ki-67 | -0.0678525 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0639152 |
| VCL | vinculin | -0.0575523 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.056182 |
| CENPF | centromere protein F, 350/400kDa | -0.0517383 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0486747 |
| HJURP | Holliday junction recognition protein | -0.0448798 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0444464 |
| PKM | pyruvate kinase, muscle | -0.0434645 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0421399 |
| ECT2 | epithelial cell transforming 2 | -0.0421344 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0420877 |
| NAV2 | neuron navigator 2 | -0.041807 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.041106 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0407767 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.040745 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0406613 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0391558 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0384592 |
| BMP2K | BMP2 inducible kinase | -0.0370583 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0367196 |
| CENPE | centromere protein E, 312kDa | -0.0363953 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0361131 |
| PGK1 | phosphoglycerate kinase 1 | -0.035741 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0353255 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.033103 |
| HDLBP | high density lipoprotein binding protein | -0.0326792 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0325912 |
| MYO5C | myosin VC | -0.0324948 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0316037 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0310732 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0307364 |
| SP100 | SP100 nuclear antigen | -0.0307023 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0290868 |
| ANLN | anillin, actin binding protein | -0.0285692 |
| LDHA | lactate dehydrogenase A | -0.0276535 |
| RRM2 | ribonucleotide reductase M2 | -0.0275091 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0272252 |
| FER1L6 | fer-1-like family member 6 | -0.0268959 |
| EZR | ezrin | -0.026847 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0265491 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0262092 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0261066 |
| CANX | calnexin | -0.0260748 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.026041 |
| ZNF217 | zinc finger protein 217 | -0.0256444 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0254724 |
| RIGI | RNA sensor RIG-I | -0.0248155 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0244696 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0240291 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.023973 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0238624 |
| HMGB1 | high mobility group box 1 | -0.0232767 |
| TPX2 | TPX2, microtubule-associated | -0.0231629 |
| PFN1 | profilin 1 | -0.022776 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0225539 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0221511 |
| ENO1 | enolase 1, (alpha) | -0.0221471 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0220403 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0217164 |
| RRBP1 | ribosome binding protein 1 | -0.0214229 |
| S100A4 | S100 calcium binding protein A4 | -0.0213757 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0213363 |
| FUS | FUS RNA binding protein | -0.0212144 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0209593 |
| TUBA1B | tubulin, alpha 1b | -0.020943 |
| CLTC | clathrin, heavy chain (Hc) | -0.0207447 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0201895 |
| DENND1A | DENN/MADD domain containing 1A | -0.0201226 |
| FAM91A1 | family with sequence similarity 91, member A1 | -0.0200508 |
| SETX | senataxin | -0.020036 |
| YBX1 | Y box binding protein 1 | -0.0199784 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0198878 |
| TUBB | tubulin, beta class I | -0.0196598 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0196482 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0195956 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0194497 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0192977 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0190078 |
| POTEF | POTE ankyrin domain family, member F | -0.0189498 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0188857 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0185032 |
| NBEA | neurobeachin | -0.0183796 |
| H1-4 | H1.4 linker histone, cluster member | -0.0183131 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0182985 |
| BCOR | BCL6 corepressor | -0.0181654 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0180912 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0180704 |
| NEBL | nebulette | -0.0180586 |
| PTMS | parathymosin | -0.0179638 |
| PLXNA2 | plexin A2 | -0.0176747 |
