| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ipatasertib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ipatasertib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0945622 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0906719 |
| MYOF | myoferlin | 0.0894355 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0854261 |
| CD44 | CD44 molecule (Indian blood group) | 0.0827503 |
| ASPH | aspartate beta-hydroxylase | 0.0813995 |
| FRMD4A | FERM domain containing 4A | 0.0811113 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0783952 |
| DST | dystonin | 0.0768671 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0751412 |
| ATXN1 | ataxin 1 | 0.0714655 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.069117 |
| RPS12 | ribosomal protein S12 | 0.0687042 |
| SMYD3 | SET and MYND domain containing 3 | 0.0661225 |
| COL6A3 | collagen, type VI, alpha 3 | 0.065092 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0650665 |
| PHF3 | PHD finger protein 3 | 0.0641583 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0625019 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0610819 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0591215 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0582316 |
| VCL | vinculin | 0.0550759 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0539714 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.053369 |
| FLNA | filamin A, alpha | 0.0532221 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0530951 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0519642 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0515523 |
| SYNJ2 | synaptojanin 2 | 0.0513869 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0496014 |
| ENO1 | enolase 1, (alpha) | 0.0478349 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0465911 |
| SEPTIN9 | septin 9 | 0.0463131 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0459955 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.045853 |
| PRELID2 | PRELI domain containing 2 | 0.0456726 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0454262 |
| BICC1 | BicC family RNA binding protein 1 | 0.0434308 |
| BPTF | bromodomain PHD finger transcription factor | 0.0429901 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0424706 |
| RPL5 | ribosomal protein L5 | 0.0419922 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0419419 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0417411 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0413833 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0410274 |
| CDK19 | cyclin-dependent kinase 19 | 0.0409958 |
| ZNF292 | zinc finger protein 292 | 0.0408722 |
| ANXA2 | annexin A2 | 0.0407821 |
| LDHA | lactate dehydrogenase A | 0.0404237 |
| NAV2 | neuron navigator 2 | 0.0404095 |
| SMAD3 | SMAD family member 3 | 0.0401647 |
| LYST | lysosomal trafficking regulator | 0.039846 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0398352 |
| RPS6 | ribosomal protein S6 | 0.039819 |
| RAD51B | RAD51 paralog B | 0.0397845 |
| RPL9 | ribosomal protein L9 | 0.0397498 |
| ZNF608 | zinc finger protein 608 | 0.0396155 |
| ERBIN | erbb2 interacting protein | 0.0391397 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0384524 |
| TNS3 | tensin 3 | 0.0384446 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0383681 |
| UTRN | utrophin | 0.0382336 |
| RPL37A | ribosomal protein L37a | 0.0378019 |
| OGA | O-GlcNAcase | 0.037538 |
| NXN | nucleoredoxin | 0.036432 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0362512 |
| RUNX1 | runt-related transcription factor 1 | 0.0362068 |
| PLPP4 | phospholipid phosphatase 4 | 0.036182 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0361636 |
| FLNB | filamin B, beta | 0.0361543 |
| RPL7A | ribosomal protein L7a | 0.0358101 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0351354 |
| EGFR | epidermal growth factor receptor | 0.0345272 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0340162 |
| COL5A1 | collagen, type V, alpha 1 | 0.0339761 |
| LRRC7 | leucine rich repeat containing 7 | 0.0338141 |
| FNIP1 | folliculin interacting protein 1 | 0.033372 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0333352 |
| RPS3 | ribosomal protein S3 | 0.0333082 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0329715 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.032704 |
| MLPH | melanophilin | 0.0324941 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.031783 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0315204 |
| PRKCA | protein kinase C, alpha | 0.0309979 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0306556 |
| RPL13A | ribosomal protein L13a | 0.0305187 |
| ZNF638 | zinc finger protein 638 | 0.0304597 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0304275 |
| TRERF1 | transcriptional regulating factor 1 | 0.0303305 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0299739 |
| RPS25 | ribosomal protein S25 | 0.0296746 |
| SVIL | supervillin | 0.0296236 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0295403 |
| RPS2 | ribosomal protein S2 | 0.0294917 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0294692 |
| VEGFA | vascular endothelial growth factor A | 0.029355 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0287651 |
| CDK13 | cyclin-dependent kinase 13 | 0.0287384 |
| INTS6 | integrator complex subunit 6 | 0.028659 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.157297 |
| FN1 | fibronectin 1 | -0.128374 |
| IER3 | immediate early response 3 | -0.120764 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.11509 |
| TMSB10 | thymosin beta 10 | -0.0963135 |
| GLIS3 | GLIS family zinc finger 3 | -0.0863023 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0800193 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0742824 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0678739 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0622936 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0605366 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0586076 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0563028 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0560628 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0544608 |
| RIGI | RNA sensor RIG-I | -0.0534213 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0532633 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0508846 |
| EGR1 | early growth response 1 | -0.0505202 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0459101 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0457709 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0420852 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0403124 |
| PTMA | prothymosin, alpha | -0.0402412 |
| RND3 | Rho family GTPase 3 | -0.038664 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0371652 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0367692 |
| RAI14 | retinoic acid induced 14 | -0.0355195 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0346111 |
| HDAC9 | histone deacetylase 9 | -0.0324713 |
| INHBA | inhibin, beta A | -0.0319451 |
| ATP13A3 | ATPase type 13A3 | -0.0319431 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0316388 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.031607 |
| IL6 | interleukin 6 | -0.0302164 |
| MX1 | MX dynamin-like GTPase 1 | -0.0299097 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0295649 |
| MAP1B | microtubule-associated protein 1B | -0.0291573 |
| PGK1 | phosphoglycerate kinase 1 | -0.0288324 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0286037 |
| DENND5A | DENN/MADD domain containing 5A | -0.0284023 |
| RBM39 | RNA binding motif protein 39 | -0.0283464 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0283066 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.027793 |
| SDC4 | syndecan 4 | -0.0274579 |
| MORF4L2 | mortality factor 4 like 2 | -0.0272037 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0269932 |
| JUN | jun proto-oncogene | -0.0262706 |
| DIAPH2 | diaphanous-related formin 2 | -0.0261221 |
| RAI1 | retinoic acid induced 1 | -0.0258587 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0258237 |
| CADM1 | cell adhesion molecule 1 | -0.025817 |
| WTAP | Wilms tumor 1 associated protein | -0.0257903 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0255567 |
| PLSCR1 | phospholipid scramblase 1 | -0.0252591 |
| SEC24A | SEC24 family member A | -0.0250497 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0250255 |
| TMSB4X | thymosin beta 4, X-linked | -0.0247287 |
| SPAG9 | sperm associated antigen 9 | -0.0246903 |
| CLMP | CXADR-like membrane protein | -0.0245015 |
| RTN4 | reticulon 4 | -0.0244957 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0239863 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0233571 |
| TNNC1 | troponin C type 1 (slow) | -0.0231058 |
| ADM | adrenomedullin | -0.0229936 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0227334 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0226326 |
| TMEM263 | transmembrane protein 263 | -0.0225711 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.022347 |
| CALR | calreticulin | -0.0223394 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0220503 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0220427 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0219528 |
| KYNU | kynureninase | -0.0216814 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0215736 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0214547 |
| RRBP1 | ribosome binding protein 1 | -0.0214305 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.021026 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0207523 |
| CRY1 | cryptochrome circadian clock 1 | -0.0204938 |
| SP100 | SP100 nuclear antigen | -0.0204626 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0204574 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0204081 |
| VIM | vimentin | -0.0200833 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0200562 |
| RNF213 | ring finger protein 213 | -0.0200359 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0199418 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0199127 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0197965 |
| TUBB | tubulin, beta class I | -0.0196943 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0195687 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0193726 |
| STC1 | stanniocalcin 1 | -0.0193033 |
| ARF4 | ADP-ribosylation factor 4 | -0.0192548 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0191783 |
| TRIM22 | tripartite motif containing 22 | -0.0191433 |
| WDR45B | WD repeat domain 45B | -0.0190458 |
| C3 | complement component 3 | -0.0188551 |
| MX2 | MX dynamin-like GTPase 2 | -0.018686 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0185076 |
