| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ipatasertib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ipatasertib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.128616 |
| TMEM156 | transmembrane protein 156 | 0.0899077 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0549266 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0545068 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0526479 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0501396 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0435611 |
| SEPTIN9 | septin 9 | 0.0433648 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0432033 |
| NRP1 | neuropilin 1 | 0.0420746 |
| SMYD3 | SET and MYND domain containing 3 | 0.0412376 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0408075 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0398724 |
| SVIL | supervillin | 0.0389097 |
| ANXA5 | annexin A5 | 0.0380487 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0376408 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0361439 |
| PCDH7 | protocadherin 7 | 0.0358341 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0358248 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0352818 |
| S100A10 | S100 calcium binding protein A10 | 0.0344592 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0342837 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0335265 |
| PTK2 | protein tyrosine kinase 2 | 0.0331115 |
| SMAD3 | SMAD family member 3 | 0.03311 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0314131 |
| ETV1 | ets variant 1 | 0.0313203 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0297452 |
| NTN4 | netrin 4 | 0.0294807 |
| PRELID2 | PRELI domain containing 2 | 0.0290554 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0289809 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.028583 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0279244 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0278779 |
| SFTPA2 | surfactant protein A2 | 0.0275489 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0273439 |
| FOXP1 | forkhead box P1 | 0.0271962 |
| ATXN1 | ataxin 1 | 0.0268289 |
| EGFR | epidermal growth factor receptor | 0.0268185 |
| BPTF | bromodomain PHD finger transcription factor | 0.0261036 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0259575 |
| LRP5 | low density lipoprotein receptor-related protein 5 | 0.0255343 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0254224 |
| RUNX1 | runt-related transcription factor 1 | 0.0251666 |
| FHIT | fragile histidine triad | 0.025083 |
| RORA | RAR-related orphan receptor A | 0.0245976 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0244466 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.024388 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0243794 |
| CD44 | CD44 molecule (Indian blood group) | 0.0241935 |
| DENND5B | DENN/MADD domain containing 5B | 0.0236829 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0234232 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0233183 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0231422 |
| RASAL2 | RAS protein activator like 2 | 0.0230384 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.022811 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0227726 |
| EMP1 | epithelial membrane protein 1 | 0.0225919 |
| JMJD1C | jumonji domain containing 1C | 0.0224781 |
| ERBIN | erbb2 interacting protein | 0.0219882 |
| TPI1 | triosephosphate isomerase 1 | 0.0219506 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0219304 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0217888 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0217156 |
| GPC6 | glypican 6 | 0.0216096 |
| IL6ST | interleukin 6 signal transducer | 0.0215547 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0215223 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.0213446 |
| FHL2 | four and a half LIM domains 2 | 0.0211933 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0209443 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0205655 |
| SIK3 | SIK family kinase 3 | 0.0204304 |
| KLF12 | Kruppel-like factor 12 | 0.0202349 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0202331 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0199429 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0198536 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.0197383 |
| SYT1 | synaptotagmin I | 0.019491 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0193666 |
| TOP1 | topoisomerase (DNA) I | 0.0192827 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0192614 |
| FNBP1 | formin binding protein 1 | 0.0191285 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0190979 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0189515 |
| PRKCA | protein kinase C, alpha | 0.018905 |
| CNKSR3 | CNKSR family member 3 | 0.018834 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.018726 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0186818 |
| ENAH | enabled homolog (Drosophila) | 0.018406 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0184008 |
| LIMA1 | LIM domain and actin binding 1 | 0.0183855 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0183851 |
| NXN | nucleoredoxin | 0.0183506 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.018296 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0182548 |
| LAMA4 | laminin, alpha 4 | 0.0181729 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0179928 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0179041 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0176343 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0175707 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.383697 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.267751 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.253548 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.155524 |
| CANX | calnexin | -0.153152 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.152771 |
| PTMA | prothymosin, alpha | -0.14902 |
| SQSTM1 | sequestosome 1 | -0.108365 |
| NRG1 | neuregulin 1 | -0.104508 |
| FN1 | fibronectin 1 | -0.0924866 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.092167 |
| TMSB10 | thymosin beta 10 | -0.0872944 |
| PLIN2 | perilipin 2 | -0.0715276 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0715065 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0679145 |
| HMGA2 | high mobility group AT-hook 2 | -0.0614449 |
| FTL | ferritin, light polypeptide | -0.0608717 |
| TMSB4X | thymosin beta 4, X-linked | -0.058945 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0553509 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0532259 |
| S100A6 | S100 calcium binding protein A6 | -0.0526229 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0491666 |
| ITGA1 | integrin, alpha 1 | -0.0490561 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0466794 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0463285 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0419106 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0414132 |
| HDLBP | high density lipoprotein binding protein | -0.0410963 |
| CALR | calreticulin | -0.0396748 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0392971 |
| H1-0 | H1.0 linker histone | -0.0391922 |
| RAI14 | retinoic acid induced 14 | -0.0391813 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.03867 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0378478 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0377535 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0376944 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0355167 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0348739 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0344625 |
| IER3 | immediate early response 3 | -0.0331352 |
| TMEM165 | transmembrane protein 165 | -0.032871 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.032704 |
| TMEM263 | transmembrane protein 263 | -0.032414 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.032322 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0322808 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0322608 |
| SUCO | SUN domain containing ossification factor | -0.030733 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0307237 |
| GLIS3 | GLIS family zinc finger 3 | -0.0296387 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0287468 |
| CENPF | centromere protein F, 350/400kDa | -0.0265138 |
| RPL35A | ribosomal protein L35a | -0.025634 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.025484 |
| GOLGA4 | golgin A4 | -0.0250681 |
| ARF1 | ADP-ribosylation factor 1 | -0.0245735 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0245485 |
| CALU | calumenin | -0.024006 |
| ARF4 | ADP-ribosylation factor 4 | -0.0237657 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0237575 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0234141 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.0233203 |
| LRRC23 | leucine rich repeat containing 23 | -0.0232598 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0229535 |
| LOX | lysyl oxidase | -0.0219708 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0218847 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0218491 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0213828 |
| ZNF217 | zinc finger protein 217 | -0.021241 |
| GNAS | GNAS complex locus | -0.0211951 |
| HMGB3 | high mobility group box 3 | -0.021038 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0209154 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0207112 |
| SRP54 | signal recognition particle 54kDa | -0.0203498 |
| HLA-B | major histocompatibility complex, class I, B | -0.0202808 |
| RRBP1 | ribosome binding protein 1 | -0.0202333 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0201715 |
| PGK1 | phosphoglycerate kinase 1 | -0.020065 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0198514 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0196354 |
| IL6 | interleukin 6 | -0.019458 |
| STC2 | stanniocalcin 2 | -0.0193667 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0192128 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0190432 |
| S100A9 | S100 calcium binding protein A9 | -0.0189127 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0188988 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0188847 |
| FAM20C | family with sequence similarity 20, member C | -0.0188695 |
| PCBP3 | poly(rC) binding protein 3 | -0.0187653 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0187544 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0186463 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0185375 |
| CADM1 | cell adhesion molecule 1 | -0.0184883 |
| LDHA | lactate dehydrogenase A | -0.0183991 |
| LAMB3 | laminin, beta 3 | -0.0182154 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0181703 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0181672 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0181125 |
| INSIG1 | insulin induced gene 1 | -0.0178475 |
| FAM114A1 | family with sequence similarity 114, member A1 | -0.0178401 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.017705 |
