| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Isocorydine perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Isocorydine_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.437289 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0582999 |
| PLAT | plasminogen activator, tissue | 0.0547685 |
| BPTF | bromodomain PHD finger transcription factor | 0.048894 |
| FMN1 | formin 1 | 0.0482165 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0473517 |
| LSAMP | limbic system-associated membrane protein | 0.0465542 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0454845 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0443977 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0440221 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0435639 |
| TLE4 | transducin-like enhancer of split 4 | 0.0410066 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0405279 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0400935 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0400258 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0398185 |
| THBS1 | thrombospondin 1 | 0.0396451 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0385886 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0373052 |
| RNF213 | ring finger protein 213 | 0.0370717 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0368288 |
| KLF6 | Kruppel-like factor 6 | 0.036782 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0366075 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0352192 |
| VCL | vinculin | 0.0351786 |
| VMP1 | vacuole membrane protein 1 | 0.0348283 |
| FAM107B | family with sequence similarity 107, member B | 0.0345305 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0343831 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0338943 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0331671 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0325077 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0318787 |
| RIGI | RNA sensor RIG-I | 0.0312995 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.031284 |
| COL1A1 | collagen, type I, alpha 1 | 0.0308316 |
| EGR1 | early growth response 1 | 0.0308273 |
| CTSB | cathepsin B | 0.0306044 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0291324 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0268581 |
| RET | ret proto-oncogene | 0.0264992 |
| PDE10A | phosphodiesterase 10A | 0.0264971 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0262946 |
| AMOTL1 | angiomotin like 1 | 0.0260273 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0246331 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0245464 |
| DST | dystonin | 0.0241802 |
| PCBP3 | poly(rC) binding protein 3 | 0.0234295 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0233874 |
| STK38L | serine/threonine kinase 38 like | 0.0233025 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0231757 |
| TENM4 | teneurin transmembrane protein 4 | 0.0230318 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0227782 |
| EXOC4 | exocyst complex component 4 | 0.02267 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0226621 |
| COL3A1 | collagen, type III, alpha 1 | 0.0218938 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0215165 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0213052 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0211145 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0210216 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0208967 |
| CRH | corticotropin releasing hormone | 0.0207158 |
| SMAD3 | SMAD family member 3 | 0.0205843 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0201484 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0197979 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0196572 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0196378 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0195985 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.0195877 |
| GSE1 | Gse1 coiled-coil protein | 0.019581 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0194618 |
| MAP1B | microtubule-associated protein 1B | 0.0193976 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0193204 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0187711 |
| ADAR | adenosine deaminase, RNA-specific | 0.0186698 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0186415 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0182636 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0180436 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.01798 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0179361 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0179209 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0176952 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0174471 |
| PLPP1 | phospholipid phosphatase 1 | 0.0173551 |
| CADM1 | cell adhesion molecule 1 | 0.0173255 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.017281 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0171502 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0170191 |
| RGS4 | regulator of G-protein signaling 4 | 0.0170146 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.0169388 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0168981 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0168439 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0168313 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0165172 |
| DNM3 | dynamin 3 | 0.0164198 |
| SEPTIN9 | septin 9 | 0.0163893 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.016249 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0161572 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0160643 |
| TPM3 | tropomyosin 3 | 0.0159121 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0156208 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.345882 |
| PTMA | prothymosin, alpha | -0.105263 |
| RPLP1 | ribosomal protein, large, P1 | -0.0642185 |
| VIM | vimentin | -0.0601462 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0513593 |
| RPS6 | ribosomal protein S6 | -0.0513113 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0474872 |
| FAM13A | family with sequence similarity 13, member A | -0.0409462 |
| DPH6 | diphthamine biosynthesis 6 | -0.0376326 |
| MEIS2 | Meis homeobox 2 | -0.0375716 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0363282 |
| HELZ | helicase with zinc finger | -0.0360704 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0347806 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0328491 |
| WDR45B | WD repeat domain 45B | -0.0324405 |
| GOLGA4 | golgin A4 | -0.0321589 |
| SETD5 | SET domain containing 5 | -0.0318387 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0315348 |
| NDRG1 | N-myc downstream regulated 1 | -0.0312019 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0279239 |
| ZNF292 | zinc finger protein 292 | -0.0278248 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0273346 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0271018 |
| RPS24 | ribosomal protein S24 | -0.0270963 |
| DTNA | dystrobrevin, alpha | -0.026877 |
| USP3 | ubiquitin specific peptidase 3 | -0.0264795 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0262611 |
| OGA | O-GlcNAcase | -0.0262036 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0257425 |
| FTL | ferritin, light polypeptide | -0.0250336 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0249126 |
| RNF145 | ring finger protein 145 | -0.0246804 |
| TMSB10 | thymosin beta 10 | -0.0244837 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0242879 |
| DSTN | destrin (actin depolymerizing factor) | -0.0239713 |
| RPS19 | ribosomal protein S19 | -0.023114 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0230239 |
| GNAS | GNAS complex locus | -0.0225836 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0224624 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.021909 |
| COPA | coatomer protein complex, subunit alpha | -0.0217679 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0214783 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0213036 |
| LPIN1 | lipin 1 | -0.0212457 |
| GLG1 | golgi glycoprotein 1 | -0.0205093 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0203431 |
| PHIP | pleckstrin homology domain interacting protein | -0.0200961 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0200754 |
| RPL34 | ribosomal protein L34 | -0.0196829 |
| TNPO1 | transportin 1 | -0.0196351 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0195299 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0194444 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0194193 |
| RPL31 | ribosomal protein L31 | -0.0191478 |
| SEPTIN2 | septin 2 | -0.0190689 |
| PKM | pyruvate kinase, muscle | -0.0188745 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0185063 |
| RTN4 | reticulon 4 | -0.0185051 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0184889 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0184523 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0182697 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0182345 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0180504 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0180253 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0179956 |
| USP34 | ubiquitin specific peptidase 34 | -0.0177805 |
| SLMAP | sarcolemma associated protein | -0.0177292 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0176724 |
| RPL19 | ribosomal protein L19 | -0.0175567 |
| RBM25 | RNA binding motif protein 25 | -0.0172982 |
| RPL32 | ribosomal protein L32 | -0.0172948 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0172724 |
| SRP54 | signal recognition particle 54kDa | -0.0172615 |
| LDHB | lactate dehydrogenase B | -0.0170396 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0168134 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0166468 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0166056 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.016564 |
| RPL28 | ribosomal protein L28 | -0.0165613 |
| NKTR | natural killer cell triggering receptor | -0.0164401 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0162067 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0161781 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0159329 |
| RPS14 | ribosomal protein S14 | -0.0159134 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0157257 |
| RAB6A | RAB6A, member RAS oncogene family | -0.015716 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0156997 |
| RPLP0 | ribosomal protein, large, P0 | -0.0156744 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0156528 |
| CEP95 | centrosomal protein 95kDa | -0.0156305 |
| RNF150 | ring finger protein 150 | -0.0155871 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0153501 |
| RNF24 | ring finger protein 24 | -0.0151741 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0151615 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0151561 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0151303 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0150647 |
| STAG2 | stromal antigen 2 | -0.0150576 |
| NUP58 | nucleoporin 58 | -0.0150415 |
| CABIN1 | calcineurin binding protein 1 | -0.0150299 |