| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Isocorydine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Isocorydine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | 0.16156 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.118829 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.115824 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0884865 |
| FN1 | fibronectin 1 | 0.0777661 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0769254 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0636265 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0589585 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0586045 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0561669 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0539979 |
| NTN4 | netrin 4 | 0.0529667 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0520971 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0509326 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0506625 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0502609 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0497226 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0490211 |
| EFNA5 | ephrin-A5 | 0.0469371 |
| ANKRD28 | ankyrin repeat domain 28 | 0.045879 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0456456 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0454319 |
| LOX | lysyl oxidase | 0.04068 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0396406 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0378941 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0374883 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0373266 |
| NAV2 | neuron navigator 2 | 0.0367686 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0356584 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0345674 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0345668 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.03336 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0331991 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0326903 |
| FAM20C | family with sequence similarity 20, member C | 0.0320087 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0316256 |
| AOPEP | aminopeptidase O (putative) | 0.0315507 |
| GLCCI1 | glucocorticoid induced 1 | 0.0311677 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | 0.0305311 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0305179 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0287219 |
| OSMR | oncostatin M receptor | 0.0284801 |
| RND3 | Rho family GTPase 3 | 0.0284352 |
| KLF6 | Kruppel-like factor 6 | 0.0282756 |
| RAI14 | retinoic acid induced 14 | 0.0281501 |
| HAS2 | hyaluronan synthase 2 | 0.0274647 |
| SMAD3 | SMAD family member 3 | 0.0269197 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0268033 |
| WLS | wntless Wnt ligand secretion mediator | 0.0266581 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0263038 |
| IL1R1 | interleukin 1 receptor, type I | 0.0262521 |
| HMGA2 | high mobility group AT-hook 2 | 0.0257401 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0256466 |
| TLR2 | toll-like receptor 2 | 0.0252737 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0248406 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0248172 |
| GLIS3 | GLIS family zinc finger 3 | 0.0247165 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0239656 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0237231 |
| ATXN1 | ataxin 1 | 0.0234377 |
| ENOSF1 | enolase superfamily member 1 | 0.0233028 |
| TMOD1 | tropomodulin 1 | 0.0232436 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0230061 |
| DUSP16 | dual specificity phosphatase 16 | 0.0229055 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0228932 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0228044 |
| SYAP1 | synapse associated protein 1 | 0.0225741 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0225317 |
| CLMP | CXADR-like membrane protein | 0.022081 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | 0.0218756 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0217669 |
| STK38L | serine/threonine kinase 38 like | 0.0217225 |
| RHCG | Rh family, C glycoprotein | 0.0210958 |
| CALU | calumenin | 0.0207935 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0205583 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0203062 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0202361 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0200273 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0196988 |
| LOXL2 | lysyl oxidase-like 2 | 0.0196717 |
| HLA-B | major histocompatibility complex, class I, B | 0.0193578 |
| FHL2 | four and a half LIM domains 2 | 0.0192859 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0191296 |
| TNNC1 | troponin C type 1 (slow) | 0.0187906 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0186696 |
| EZR | ezrin | 0.0185333 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0184815 |
| CCDC68 | coiled-coil domain containing 68 | 0.0183476 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0183357 |
| CEP250 | centrosomal protein 250kDa | 0.0183111 |
| SEPTIN9 | septin 9 | 0.0182213 |
| RPL6 | ribosomal protein L6 | 0.0182012 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0181363 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0179718 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0179506 |
| RNF213 | ring finger protein 213 | 0.0179452 |
| MYO10 | myosin X | 0.0179 |
| RNF144A | ring finger protein 144A | 0.0178238 |
| CDH13 | cadherin 13 | 0.017781 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0174561 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.188827 |
| FTL | ferritin, light polypeptide | -0.140229 |
| TMSB10 | thymosin beta 10 | -0.136664 |
| VIM | vimentin | -0.129533 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.104788 |
| PTMA | prothymosin, alpha | -0.0993129 |
| PCBP2 | poly(rC) binding protein 2 | -0.0926931 |
| GOLGA4 | golgin A4 | -0.0830396 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0811408 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0808435 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0788982 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0753291 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0726788 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0680226 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0676864 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0656791 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0626969 |
| RPS6 | ribosomal protein S6 | -0.0614522 |
| RPLP1 | ribosomal protein, large, P1 | -0.0591902 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0579719 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.056662 |
| PKM | pyruvate kinase, muscle | -0.0551954 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0544821 |
| RPL35A | ribosomal protein L35a | -0.0534118 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0526345 |
| SETD5 | SET domain containing 5 | -0.0525204 |
| RBM39 | RNA binding motif protein 39 | -0.0514991 |
| RIOK3 | RIO kinase 3 | -0.0511491 |
| NDRG1 | N-myc downstream regulated 1 | -0.0499918 |
| USP34 | ubiquitin specific peptidase 34 | -0.0495428 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.048375 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0471725 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0464038 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0462604 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0450195 |
| GPC6 | glypican 6 | -0.0444198 |
| HELZ | helicase with zinc finger | -0.0441684 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0441321 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0436177 |
| PLIN2 | perilipin 2 | -0.0435595 |
| RPS25 | ribosomal protein S25 | -0.0433533 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0426439 |
| RPL31 | ribosomal protein L31 | -0.0420081 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0419624 |
| POTEF | POTE ankyrin domain family, member F | -0.0417853 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0415847 |
| SRP54 | signal recognition particle 54kDa | -0.0414409 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0401101 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.040074 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0387623 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0384183 |
| GNAS | GNAS complex locus | -0.0378503 |
| RPS8 | ribosomal protein S8 | -0.0377809 |
| RPS19 | ribosomal protein S19 | -0.0373274 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0369037 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0364264 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0361712 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0356397 |
| B2M | beta-2-microglobulin | -0.0354959 |
| RPS24 | ribosomal protein S24 | -0.0354943 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0354663 |
| COG5 | component of oligomeric golgi complex 5 | -0.0352591 |
| WDR45B | WD repeat domain 45B | -0.0349904 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0345576 |
| VDAC1 | voltage-dependent anion channel 1 | -0.034267 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0332751 |
| RPL9 | ribosomal protein L9 | -0.0327326 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.032443 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0321569 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0317271 |
| RPS23 | ribosomal protein S23 | -0.0314892 |
| OGA | O-GlcNAcase | -0.0314504 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0313511 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0308437 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0307376 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0303192 |
| SUCO | SUN domain containing ossification factor | -0.0300547 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0300007 |
| GLG1 | golgi glycoprotein 1 | -0.0299892 |
| INTS6 | integrator complex subunit 6 | -0.0296241 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0295381 |
| RPLP0 | ribosomal protein, large, P0 | -0.0294881 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.029382 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0290637 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0290363 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0288571 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0285418 |
| RPL37A | ribosomal protein L37a | -0.0285256 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0284336 |
| RPS5 | ribosomal protein S5 | -0.0283471 |
| ZNF292 | zinc finger protein 292 | -0.0283031 |
| YBX1 | Y box binding protein 1 | -0.0283012 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0282881 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0282393 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0279408 |
| XPO1 | exportin 1 | -0.0279199 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.027902 |
| MORF4L2 | mortality factor 4 like 2 | -0.0277952 |
| WASF2 | WAS protein family, member 2 | -0.0277166 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0276394 |
