| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Isocorydine perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Isocorydine_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.231762 |
| NDRG1 | N-myc downstream regulated 1 | 0.15998 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0952598 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0888827 |
| TPM3 | tropomyosin 3 | 0.0862723 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0846842 |
| HMGA1 | high mobility group AT-hook 1 | 0.0829687 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0826024 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0821537 |
| POTEF | POTE ankyrin domain family, member F | 0.0792692 |
| PLEC | plectin | 0.0761144 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.072081 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0708858 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0708118 |
| MSN | moesin | 0.0685039 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0669311 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.061145 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0605407 |
| VEGFA | vascular endothelial growth factor A | 0.0584967 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.056407 |
| ARRDC3 | arrestin domain containing 3 | 0.0551613 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0517483 |
| CTSB | cathepsin B | 0.0498742 |
| LAMB3 | laminin, beta 3 | 0.0498661 |
| CALR | calreticulin | 0.0487869 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0480063 |
| ENO1 | enolase 1, (alpha) | 0.0479997 |
| HLA-B | major histocompatibility complex, class I, B | 0.0460598 |
| LDHA | lactate dehydrogenase A | 0.0449665 |
| DSPP | dentin sialophosphoprotein | 0.0441287 |
| PCBP2 | poly(rC) binding protein 2 | 0.0439093 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0434894 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0425988 |
| G0S2 | G0/G1 switch 2 | 0.0413186 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0409862 |
| LAMC2 | laminin, gamma 2 | 0.0401073 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0397668 |
| MT2A | metallothionein 2A | 0.0376661 |
| UBC | ubiquitin C | 0.0368477 |
| F11R | F11 receptor | 0.0366547 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0362738 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0348657 |
| BRD2 | bromodomain containing 2 | 0.0348503 |
| MKI67 | marker of proliferation Ki-67 | 0.0347182 |
| RPL13A | ribosomal protein L13a | 0.0342811 |
| FLNA | filamin A, alpha | 0.0341011 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.033658 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0330923 |
| MXD1 | MAX dimerization protein 1 | 0.0328128 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0321548 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0317494 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0314082 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0310343 |
| HLA-A | major histocompatibility complex, class I, A | 0.0309616 |
| TXNIP | thioredoxin interacting protein | 0.0305762 |
| RPL5 | ribosomal protein L5 | 0.0303723 |
| EZR | ezrin | 0.0300737 |
| RPS12 | ribosomal protein S12 | 0.0299011 |
| EGR1 | early growth response 1 | 0.0287359 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0285156 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0278385 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0278256 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0275937 |
| NAV2 | neuron navigator 2 | 0.0273737 |
| MYO5B | myosin VB | 0.0273564 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0271063 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0267213 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0259852 |
| HDGF | hepatoma-derived growth factor | 0.025826 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.025683 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0256618 |
| FOSL1 | FOS-like antigen 1 | 0.025362 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0252578 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0252172 |
| SQSTM1 | sequestosome 1 | 0.0246043 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.024517 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0236392 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0233046 |
| RND3 | Rho family GTPase 3 | 0.023062 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0229901 |
| RPL3 | ribosomal protein L3 | 0.0227675 |
| SET | SET nuclear proto-oncogene | 0.0226948 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0226347 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0223842 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0223068 |
| CFB | complement factor B | 0.0218592 |
| MYO10 | myosin X | 0.0215661 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0214986 |
| GANAB | glucosidase, alpha; neutral AB | 0.0212491 |
| RPS2 | ribosomal protein S2 | 0.0212069 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0211909 |
| KRT19 | keratin 19, type I | 0.0210098 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0209641 |
| KLF10 | Kruppel-like factor 10 | 0.0209396 |
| STC2 | stanniocalcin 2 | 0.0208102 |
| ACTG1 | actin gamma 1 | 0.0206882 |
| MAP1B | microtubule-associated protein 1B | 0.0205859 |
| CD44 | CD44 molecule (Indian blood group) | 0.0205407 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0202503 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0202329 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113404 |
| PTMA | prothymosin, alpha | -0.101971 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0974121 |
| FN1 | fibronectin 1 | -0.0907168 |
| TMSB10 | thymosin beta 10 | -0.0838704 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0792973 |
| RPLP1 | ribosomal protein, large, P1 | -0.0754585 |
| S100A6 | S100 calcium binding protein A6 | -0.0702727 |
| LMO7 | LIM domain 7 | -0.0702567 |
| RPL34 | ribosomal protein L34 | -0.0646999 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0595526 |
| TMSB4X | thymosin beta 4, X-linked | -0.0571323 |
| S100A10 | S100 calcium binding protein A10 | -0.0550559 |
| GNAS | GNAS complex locus | -0.0545709 |
| CD2AP | CD2-associated protein | -0.0512397 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0508779 |
| RPLP0 | ribosomal protein, large, P0 | -0.0505029 |
| RPS24 | ribosomal protein S24 | -0.0503334 |
| FTL | ferritin, light polypeptide | -0.0486274 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0463142 |
| MYO6 | myosin VI | -0.0459759 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0458511 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0449759 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0447055 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0443707 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0433236 |
| TKT | transketolase | -0.0429542 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.041963 |
| CCND1 | cyclin D1 | -0.0418871 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0417027 |
| ERBIN | erbb2 interacting protein | -0.0411108 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0407791 |
| CERT1 | ceramide transporter 1 | -0.0403138 |
| RPL32 | ribosomal protein L32 | -0.0402875 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0402113 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0395935 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.039431 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0388778 |
| TMEM263 | transmembrane protein 263 | -0.038716 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0381223 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.037357 |
| GOLGA4 | golgin A4 | -0.0373319 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0366835 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.036477 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0354352 |
| HDLBP | high density lipoprotein binding protein | -0.03519 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0349915 |
| COPA | coatomer protein complex, subunit alpha | -0.0347468 |
| TOP1 | topoisomerase (DNA) I | -0.0346309 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.03445 |
| TFG | TRK-fused gene | -0.0338598 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0337199 |
| VCL | vinculin | -0.033478 |
| PGK1 | phosphoglycerate kinase 1 | -0.0326825 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0325219 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0324736 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0324301 |
| RPS23 | ribosomal protein S23 | -0.0323744 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0322519 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0322353 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0322267 |
| RPS5 | ribosomal protein S5 | -0.0321296 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.032005 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0316655 |
| RPL31 | ribosomal protein L31 | -0.0315846 |
| RPL4 | ribosomal protein L4 | -0.0313195 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0313126 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0311998 |
| NF1 | neurofibromin 1 | -0.0304656 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0304489 |
| FNIP1 | folliculin interacting protein 1 | -0.0301607 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0299354 |
| JMJD1C | jumonji domain containing 1C | -0.0298643 |
| FBXO34 | F-box protein 34 | -0.029798 |
| CDC73 | cell division cycle 73 | -0.0295298 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0290175 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0286339 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0285535 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0285003 |
| RPL30 | ribosomal protein L30 | -0.0282929 |
| RPL14 | ribosomal protein L14 | -0.0280536 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0273287 |
| ASPH | aspartate beta-hydroxylase | -0.0269233 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0268321 |
| RBM39 | RNA binding motif protein 39 | -0.0265349 |
| PALLD | palladin, cytoskeletal associated protein | -0.0264523 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0259903 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0259765 |
| FCHO2 | FCH domain only 2 | -0.0258325 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0255863 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0250766 |
| EFNA5 | ephrin-A5 | -0.0248564 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0248112 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0246509 |
| PHF3 | PHD finger protein 3 | -0.0245047 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0244669 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0244579 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0243504 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0242603 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0242419 |
