| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Isocorydine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Isocorydine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.248499 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.215903 |
| GDA | guanine deaminase | 0.113609 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0932465 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0854331 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0692922 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.068497 |
| CDH13 | cadherin 13 | 0.0666515 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0660885 |
| FMNL2 | formin-like 2 | 0.0651044 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0647243 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0640703 |
| COL5A2 | collagen, type V, alpha 2 | 0.0627042 |
| CD109 | CD109 molecule | 0.0578655 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0575767 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0574362 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.054638 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0518601 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0490545 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0469839 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.046602 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.046167 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0460433 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0458376 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0443941 |
| AUTS2 | autism susceptibility candidate 2 | 0.0435742 |
| NTN4 | netrin 4 | 0.0432494 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0425301 |
| CD44 | CD44 molecule (Indian blood group) | 0.0420784 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0418961 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0417314 |
| CTBP2 | C-terminal binding protein 2 | 0.0415342 |
| EZR | ezrin | 0.0412501 |
| SMAD2 | SMAD family member 2 | 0.0406671 |
| ENO1 | enolase 1, (alpha) | 0.040399 |
| INHBA | inhibin, beta A | 0.0401838 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0395544 |
| ANXA2 | annexin A2 | 0.0391407 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0389758 |
| PYGL | phosphorylase, glycogen, liver | 0.0387481 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0386489 |
| RPL26 | ribosomal protein L26 | 0.0383043 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0379981 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0375678 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0373796 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0369702 |
| SVIL | supervillin | 0.0369469 |
| HLA-B | major histocompatibility complex, class I, B | 0.0351097 |
| VIM | vimentin | 0.0350703 |
| FLNB | filamin B, beta | 0.0334747 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0325758 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0320665 |
| ATXN1 | ataxin 1 | 0.031881 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0317338 |
| MFSD12 | major facilitator superfamily domain containing 12 | 0.0317202 |
| RPS8 | ribosomal protein S8 | 0.0315039 |
| TBXT | T-box transcription factor T | 0.0306361 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0305956 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0305719 |
| RPL13A | ribosomal protein L13a | 0.0304918 |
| SQSTM1 | sequestosome 1 | 0.0302069 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0302036 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0302006 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0300681 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0296633 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0296383 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0292897 |
| FAT1 | FAT atypical cadherin 1 | 0.0291429 |
| BMP6 | bone morphogenetic protein 6 | 0.028565 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0278009 |
| TPM3 | tropomyosin 3 | 0.0273035 |
| STC2 | stanniocalcin 2 | 0.0271122 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0270747 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0268774 |
| GANAB | glucosidase, alpha; neutral AB | 0.026799 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0266898 |
| MAP7 | microtubule-associated protein 7 | 0.0266652 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0264966 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0263005 |
| HDAC4 | histone deacetylase 4 | 0.026258 |
| IL6 | interleukin 6 | 0.0261759 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0259459 |
| RHOB | ras homolog family member B | 0.0257502 |
| SEPTIN9 | septin 9 | 0.0256523 |
| RPL6 | ribosomal protein L6 | 0.0254661 |
| FLNA | filamin A, alpha | 0.0253912 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0252509 |
| CTSL | cathepsin L | 0.0246924 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0246747 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0246599 |
| LDHA | lactate dehydrogenase A | 0.0236023 |
| DNER | delta/notch-like EGF repeat containing | 0.0234639 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0234102 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0233857 |
| FAM107B | family with sequence similarity 107, member B | 0.0229132 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0226107 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0222966 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0220961 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0219543 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0218036 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.173537 |
| PTMA | prothymosin, alpha | -0.0926657 |
| EFNA5 | ephrin-A5 | -0.0830199 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0825852 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0799684 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0764666 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.076089 |
| NRCAM | neuronal cell adhesion molecule | -0.0726055 |
| ASPH | aspartate beta-hydroxylase | -0.0722359 |
| RGS2 | regulator of G-protein signaling 2 | -0.0660499 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0657374 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0649941 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0643543 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0618776 |
| RBM39 | RNA binding motif protein 39 | -0.0615576 |
| VCL | vinculin | -0.0613737 |
| FTL | ferritin, light polypeptide | -0.0603595 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0600659 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.059411 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0542829 |
| RPLP1 | ribosomal protein, large, P1 | -0.0541617 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0540246 |
| MYOF | myoferlin | -0.0489326 |
| RPS24 | ribosomal protein S24 | -0.0477765 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0472675 |
| RPL31 | ribosomal protein L31 | -0.046865 |
| OGA | O-GlcNAcase | -0.0446692 |
| NEK7 | NIMA-related kinase 7 | -0.0430996 |
| TXNRD1 | thioredoxin reductase 1 | -0.043043 |
| TMSB10 | thymosin beta 10 | -0.0404984 |
| MFF | mitochondrial fission factor | -0.0404447 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0398958 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0393112 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0388367 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0378777 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0375067 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0370611 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0363564 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0359527 |
| MORF4L2 | mortality factor 4 like 2 | -0.0356764 |
| GNAS | GNAS complex locus | -0.0354514 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.035415 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0350555 |
| RTN4 | reticulon 4 | -0.0345769 |
| GOLGA4 | golgin A4 | -0.0344663 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0342599 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.033998 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0333791 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0332213 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0328413 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.032823 |
| PCBP3 | poly(rC) binding protein 3 | -0.0320296 |
| PRKD3 | protein kinase D3 | -0.0319764 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0317191 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0313091 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.031021 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.03068 |
| TNPO1 | transportin 1 | -0.0303084 |
| MATR3 | matrin 3 | -0.0300929 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0296935 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0293249 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0292575 |
| RBM25 | RNA binding motif protein 25 | -0.0291167 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0289884 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.028498 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0284892 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0280602 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0280497 |
| SRPK2 | SRSF protein kinase 2 | -0.0277885 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.0273557 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.026794 |
| SEPTIN7 | septin 7 | -0.0267678 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0265534 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0264697 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0263133 |
| DIAPH3 | diaphanous-related formin 3 | -0.0262276 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0260156 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0257816 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0257198 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0256221 |
| PLCB4 | phospholipase C, beta 4 | -0.0255512 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0255351 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0255301 |
| NCKAP5 | NCK-associated protein 5 | -0.0252134 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0248908 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0246269 |
| RPS6 | ribosomal protein S6 | -0.0245468 |
| XPO1 | exportin 1 | -0.0244048 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0243316 |
| RTN1 | reticulon 1 | -0.0240104 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0236839 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0236049 |
| SETD5 | SET domain containing 5 | -0.0235057 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0234782 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0230947 |
| PALLD | palladin, cytoskeletal associated protein | -0.0230127 |
| USP34 | ubiquitin specific peptidase 34 | -0.0229889 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0229779 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0228474 |
| PCDH15 | protocadherin-related 15 | -0.0228407 |
