| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Isocorydine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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152 genes differentially expressed following the Isocorydine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.177092 |
| IGF2 | insulin-like growth factor 2 | 0.175826 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.133018 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.130569 |
| RAB7A | RAB7A, member RAS oncogene family | 0.125289 |
| FBXL8 | F-box and leucine-rich repeat protein 8 | 0.122895 |
| ANKRD11 | ankyrin repeat domain 11 | 0.120091 |
| JMJD1C | jumonji domain containing 1C | 0.10201 |
| CD109 | CD109 molecule | 0.101791 |
| PGK1 | phosphoglycerate kinase 1 | 0.101069 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0923152 |
| SBF2 | SET binding factor 2 | 0.091054 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0910407 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0895603 |
| DTNA | dystrobrevin, alpha | 0.0821213 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0786306 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0783139 |
| ENO1 | enolase 1, (alpha) | 0.0710062 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.066642 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0661909 |
| PIPOX | pipecolic acid oxidase | 0.0653444 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0643758 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0638836 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0624125 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0591822 |
| CKAP4 | cytoskeleton-associated protein 4 | 0.0573724 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | 0.056805 |
| ZNF292 | zinc finger protein 292 | 0.0533289 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0530529 |
| JAK1 | Janus kinase 1 | 0.0521085 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0518139 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0514484 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0472594 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0466598 |
| RPL37A | ribosomal protein L37a | 0.0455287 |
| ATXN1 | ataxin 1 | 0.0452703 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0450817 |
| MED13L | mediator complex subunit 13-like | 0.0443643 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0438425 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0429737 |
| EZR | ezrin | 0.0428921 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0417582 |
| TSC22D1 | TSC22 domain family, member 1 | 0.040621 |
| INHBA | inhibin, beta A | 0.0404888 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0384465 |
| TENM3 | teneurin transmembrane protein 3 | 0.0382143 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0381103 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0370611 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0361852 |
| RPL35A | ribosomal protein L35a | 0.0359756 |
| PDZD8 | PDZ domain containing 8 | 0.0346756 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0327427 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0326348 |
| LMO7 | LIM domain 7 | 0.0309289 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0297113 |
| DST | dystonin | 0.0290837 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0281087 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0259917 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0242487 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0219052 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0206649 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0196906 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0193348 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.019193 |
| STK24 | serine/threonine kinase 24 | 0.0182914 |
| TXNIP | thioredoxin interacting protein | 0.0154314 |
| DOCK5 | dedicator of cytokinesis 5 | 0.014095 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0128997 |
| STC1 | stanniocalcin 1 | 0.0128908 |
| SPAG9 | sperm associated antigen 9 | 0.0120339 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0120307 |
| ANXA2 | annexin A2 | 0.0115533 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0110137 |
| GPC6 | glypican 6 | 0.0107367 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0101636 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0070846 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.00401815 |
| ASPH | aspartate beta-hydroxylase | 0.00289816 |
| CADM2 | cell adhesion molecule 2 | 0.00172958 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.315972 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.187566 |
| PTMA | prothymosin, alpha | -0.169503 |
| VIM | vimentin | -0.162329 |
| EGFR | epidermal growth factor receptor | -0.154979 |
| TMSB10 | thymosin beta 10 | -0.136046 |
| FN1 | fibronectin 1 | -0.134565 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.119641 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.11197 |
| HMGA2 | high mobility group AT-hook 2 | -0.111361 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.103429 |
| TPM4 | tropomyosin 4 | -0.100861 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0991346 |
| MYO6 | myosin VI | -0.0968017 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0962513 |
| FTL | ferritin, light polypeptide | -0.0835185 |
| PTK2 | protein tyrosine kinase 2 | -0.079688 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0751365 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0744982 |
| NDRG1 | N-myc downstream regulated 1 | -0.069647 |
| RPS6 | ribosomal protein S6 | -0.0682983 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0680617 |
| RTN4 | reticulon 4 | -0.0674597 |
| ARRDC3 | arrestin domain containing 3 | -0.0673443 |
| MYO1E | myosin IE | -0.0639483 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0636842 |
| SLTM | SAFB-like, transcription modulator | -0.0635693 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0608637 |
| GOLGA4 | golgin A4 | -0.0600729 |
| CD44 | CD44 molecule (Indian blood group) | -0.0597723 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0574307 |
| EFNA5 | ephrin-A5 | -0.0560528 |
| LDHA | lactate dehydrogenase A | -0.0555173 |
| PRKCA | protein kinase C, alpha | -0.0511384 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0495313 |
| TOP1 | topoisomerase (DNA) I | -0.0464937 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0422383 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0399603 |
| PDE10A | phosphodiesterase 10A | -0.0392204 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0392001 |
| RPS3 | ribosomal protein S3 | -0.0379639 |
| PEG10 | paternally expressed 10 | -0.0376776 |
| PRELID2 | PRELI domain containing 2 | -0.0365855 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0356495 |
| ATP11A | ATPase, class VI, type 11A | -0.0316901 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0316811 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0313364 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.030606 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0278828 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0265667 |
| RPL34 | ribosomal protein L34 | -0.0265083 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0262966 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0214764 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0212419 |
| MT2A | metallothionein 2A | -0.0190321 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0188364 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0182412 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0179594 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0171076 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0170422 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0167 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0147292 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0107992 |
| CANX | calnexin | -0.0104034 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.00934234 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.00900192 |
| GOLGB1 | golgin B1 | -0.0041105 |
| FLNB | filamin B, beta | -0.00384367 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.00338778 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -8.98185E-4 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -2.96615E-4 |
| USP34 | ubiquitin specific peptidase 34 | -2.85468E-4 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -1.73808E-4 |
