| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Isocorydine perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Isocorydine_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.162053 |
| HDAC9 | histone deacetylase 9 | 0.11075 |
| PYGB | phosphorylase, glycogen; brain | 0.0991996 |
| VCL | vinculin | 0.0927628 |
| GLI2 | GLI family zinc finger 2 | 0.0828617 |
| EGFR | epidermal growth factor receptor | 0.0796054 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0789804 |
| TXNRD1 | thioredoxin reductase 1 | 0.0769462 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0764416 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0735408 |
| RPS8 | ribosomal protein S8 | 0.0724339 |
| MKI67 | marker of proliferation Ki-67 | 0.0711149 |
| PDGFC | platelet derived growth factor C | 0.0705533 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0678258 |
| RPL26 | ribosomal protein L26 | 0.0642403 |
| ANXA1 | annexin A1 | 0.0629266 |
| GSE1 | Gse1 coiled-coil protein | 0.0574486 |
| FOXP1 | forkhead box P1 | 0.0562249 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0558427 |
| IGF2 | insulin-like growth factor 2 | 0.0530868 |
| LOXL3 | lysyl oxidase-like 3 | 0.0526222 |
| ENO1 | enolase 1, (alpha) | 0.0520043 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0512167 |
| TJP1 | tight junction protein 1 | 0.0503381 |
| RPS12 | ribosomal protein S12 | 0.049972 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.049782 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0490716 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0485608 |
| ZNF608 | zinc finger protein 608 | 0.0483428 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0476603 |
| PKM | pyruvate kinase, muscle | 0.0474568 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.046773 |
| RPS2 | ribosomal protein S2 | 0.0466483 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0458581 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0451812 |
| RPL35A | ribosomal protein L35a | 0.0436964 |
| TPM4 | tropomyosin 4 | 0.0436466 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0420599 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.041987 |
| POTEF | POTE ankyrin domain family, member F | 0.0407514 |
| RPS3 | ribosomal protein S3 | 0.0406145 |
| TPM3 | tropomyosin 3 | 0.0397312 |
| KLF6 | Kruppel-like factor 6 | 0.0396318 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0395002 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0381481 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0381035 |
| AMOTL2 | angiomotin like 2 | 0.0378225 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0373472 |
| CORO1C | coronin, actin binding protein, 1C | 0.0371583 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0365186 |
| GANAB | glucosidase, alpha; neutral AB | 0.0359855 |
| PCBP2 | poly(rC) binding protein 2 | 0.0358656 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0357118 |
| RPL13A | ribosomal protein L13a | 0.0355448 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0350725 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 | 0.0350523 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0348254 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0346764 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0337792 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0328746 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0327426 |
| RPL36 | ribosomal protein L36 | 0.0325613 |
| BRD4 | bromodomain containing 4 | 0.0324113 |
| RPL3 | ribosomal protein L3 | 0.0320441 |
| SEPTIN9 | septin 9 | 0.0311418 |
| MYO5C | myosin VC | 0.0305577 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0305423 |
| PFN1 | profilin 1 | 0.0303003 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0301413 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0298066 |
| SQSTM1 | sequestosome 1 | 0.0295902 |
| GLI3 | GLI family zinc finger 3 | 0.0290157 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.02889 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0285744 |
| MACROD2 | MACRO domain containing 2 | 0.0284863 |
| RPL23 | ribosomal protein L23 | 0.0284536 |
| RHOA | ras homolog family member A | 0.0280987 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0275875 |
| HMGA1 | high mobility group AT-hook 1 | 0.0272811 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0271873 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0270976 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0269411 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0267609 |
| BMP2K | BMP2 inducible kinase | 0.0264951 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0264303 |
| SON | SON DNA binding protein | 0.0261525 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.0256235 |
| NCKAP1 | NCK-associated protein 1 | 0.025166 |
| TRERF1 | transcriptional regulating factor 1 | 0.0251456 |
| KIF5B | kinesin family member 5B | 0.0250853 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | 0.024635 |
| ADAR | adenosine deaminase, RNA-specific | 0.0245845 |
| ANLN | anillin, actin binding protein | 0.024389 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0242992 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.0242967 |
| GTF2I | general transcription factor IIi | 0.0242026 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0241178 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0238593 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0238394 |
| DUSP4 | dual specificity phosphatase 4 | 0.023787 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.182126 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.172594 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.14018 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.134828 |
| PTMA | prothymosin, alpha | -0.105948 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0956054 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0852466 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0827705 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0696536 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.069412 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0655054 |
| EVI5 | ecotropic viral integration site 5 | -0.0638821 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0615606 |
| RPLP1 | ribosomal protein, large, P1 | -0.059619 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.05856 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0577061 |
| S100A6 | S100 calcium binding protein A6 | -0.0482714 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0473543 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0471262 |
| ECT2 | epithelial cell transforming 2 | -0.0451975 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0444372 |
| RPLP0 | ribosomal protein, large, P0 | -0.0442846 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.042836 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0420345 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0419393 |
| INTS6 | integrator complex subunit 6 | -0.0414309 |
| NFIA | nuclear factor I/A | -0.0410485 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0407247 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.03936 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0372135 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0368466 |
| RBM39 | RNA binding motif protein 39 | -0.0366521 |
| RBM25 | RNA binding motif protein 25 | -0.0364853 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0359714 |
| GOLGA4 | golgin A4 | -0.0355131 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0347132 |
| QKI | QKI, KH domain containing, RNA binding | -0.034644 |
| PRELID2 | PRELI domain containing 2 | -0.0345717 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0345524 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0343067 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0341843 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0341669 |
| DIAPH2 | diaphanous-related formin 2 | -0.033746 |
| HELZ | helicase with zinc finger | -0.0334214 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0331143 |
| COG6 | component of oligomeric golgi complex 6 | -0.032837 |
| FHIT | fragile histidine triad | -0.0328132 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0327962 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0326565 |
| NEBL | nebulette | -0.0320941 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0319268 |
| XPO1 | exportin 1 | -0.0311507 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0311475 |
| RRBP1 | ribosome binding protein 1 | -0.0311226 |
| MORF4L2 | mortality factor 4 like 2 | -0.0308508 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0307693 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0307387 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.0305826 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0304885 |
| SEC24D | SEC24 family member D | -0.0302011 |
| GPHN | gephyrin | -0.0296224 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0296087 |
| TMSB10 | thymosin beta 10 | -0.0293418 |
| TMEM135 | transmembrane protein 135 | -0.029021 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0290069 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0285224 |
| GNAS | GNAS complex locus | -0.0283644 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0281951 |
| ZNF217 | zinc finger protein 217 | -0.0281876 |
| THOC2 | THO complex 2 | -0.0280882 |
| RPL31 | ribosomal protein L31 | -0.027741 |
| TMEM41B | transmembrane protein 41B | -0.0277399 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0276093 |
| RHBDD1 | rhomboid domain containing 1 | -0.0276091 |
| TOP1 | topoisomerase (DNA) I | -0.0274841 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0269057 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0267076 |
| RPS24 | ribosomal protein S24 | -0.0266861 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0258458 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0258297 |
| ZNF106 | zinc finger protein 106 | -0.0255669 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0255267 |
| MSI2 | musashi RNA-binding protein 2 | -0.0253161 |
| TMEM263 | transmembrane protein 263 | -0.0252807 |
| DENND1A | DENN/MADD domain containing 1A | -0.0249069 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0247826 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.024755 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0247194 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0245463 |
| TNPO1 | transportin 1 | -0.0244375 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0244351 |
| NBEAL1 | neurobeachin-like 1 | -0.0244045 |
| ZNF638 | zinc finger protein 638 | -0.0243448 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0242398 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0238818 |
| RPL14 | ribosomal protein L14 | -0.0238411 |
| NBEA | neurobeachin | -0.0238366 |
| COMMD10 | COMM domain containing 10 | -0.0237502 |
| CENPE | centromere protein E, 312kDa | -0.0230821 |
| MATR3 | matrin 3 | -0.0230727 |
