| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivabradine (hydrochloride) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ivabradine (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.115348 |
| AHNAK | AHNAK nucleoprotein | 0.111744 |
| SMAD3 | SMAD family member 3 | 0.0958547 |
| APP | amyloid beta (A4) precursor protein | 0.0946329 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0946097 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0897232 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0822187 |
| MT1X | metallothionein 1X | 0.0763532 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0693905 |
| MCL1 | myeloid cell leukemia 1 | 0.0622348 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0618013 |
| PTMA | prothymosin, alpha | 0.0598168 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.057794 |
| FAM13A | family with sequence similarity 13, member A | 0.0576265 |
| ENO1 | enolase 1, (alpha) | 0.0570813 |
| OGA | O-GlcNAcase | 0.0561837 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.055259 |
| ASPH | aspartate beta-hydroxylase | 0.0525581 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0520897 |
| EFNA5 | ephrin-A5 | 0.0512055 |
| CCNY | cyclin Y | 0.0507778 |
| MT2A | metallothionein 2A | 0.0501242 |
| EZR | ezrin | 0.0494069 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0483635 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0476009 |
| LAMB3 | laminin, beta 3 | 0.0473312 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0471405 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0467354 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0457773 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0455285 |
| FLNB | filamin B, beta | 0.0445778 |
| ABI1 | abl-interactor 1 | 0.0434553 |
| PCBP2 | poly(rC) binding protein 2 | 0.0411172 |
| CD2AP | CD2-associated protein | 0.0405572 |
| EHBP1 | EH domain binding protein 1 | 0.0405462 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0393532 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0393034 |
| RBM39 | RNA binding motif protein 39 | 0.0379928 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0378506 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0371372 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0369888 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0369186 |
| DST | dystonin | 0.0366166 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0359798 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0358886 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0349773 |
| CP | ceruloplasmin (ferroxidase) | 0.0346445 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0335286 |
| SDC4 | syndecan 4 | 0.0332163 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0328566 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0325318 |
| RNF149 | ring finger protein 149 | 0.0312689 |
| MYOF | myoferlin | 0.0308336 |
| NIBAN2 | niban apoptosis regulator 2 | 0.030808 |
| ITGA6 | integrin, alpha 6 | 0.0299253 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0296733 |
| RCOR1 | REST corepressor 1 | 0.0294433 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0290388 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0289737 |
| TPM3 | tropomyosin 3 | 0.0283218 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0279872 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0279594 |
| KIF13B | kinesin family member 13B | 0.0278303 |
| RPS3 | ribosomal protein S3 | 0.0275426 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0272736 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0272208 |
| DSPP | dentin sialophosphoprotein | 0.0271005 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0267873 |
| RPL3 | ribosomal protein L3 | 0.026664 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0264769 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0264365 |
| YTHDC1 | YTH domain containing 1 | 0.0263936 |
| FAM162A | family with sequence similarity 162, member A | 0.0263028 |
| DIAPH1 | diaphanous-related formin 1 | 0.0262538 |
| PARD3 | par-3 family cell polarity regulator | 0.025611 |
| PRELID2 | PRELI domain containing 2 | 0.0253653 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0251844 |
| MEF2A | myocyte enhancer factor 2A | 0.0251431 |
| SPAG9 | sperm associated antigen 9 | 0.0247948 |
| CD47 | CD47 molecule | 0.0246238 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0245492 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0243054 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0242823 |
| RNASET2 | ribonuclease T2 | 0.0242485 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0241367 |
| HNF1B | HNF1 homeobox B | 0.0240505 |
| AXL | AXL receptor tyrosine kinase | 0.0240267 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.023962 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0238252 |
| APOL1 | apolipoprotein L, 1 | 0.0236719 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0236315 |
| YAP1 | Yes-associated protein 1 | 0.0234219 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0232678 |
| CCNG2 | cyclin G2 | 0.0231722 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0230158 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.022971 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0229469 |
| RPL4 | ribosomal protein L4 | 0.0227238 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0224386 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0223809 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.296451 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.150585 |
| HMGA1 | high mobility group AT-hook 1 | -0.135818 |
| KRT19 | keratin 19, type I | -0.123432 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0956434 |
| RPL35A | ribosomal protein L35a | -0.0782736 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0780277 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0780052 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.07779 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.07508 |
| ACTG1 | actin gamma 1 | -0.0679001 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0623953 |
| MMP7 | matrix metallopeptidase 7 | -0.0613958 |
| UBC | ubiquitin C | -0.0595967 |
| DTNA | dystrobrevin, alpha | -0.0576293 |
| S100A6 | S100 calcium binding protein A6 | -0.0561273 |
| RPS6 | ribosomal protein S6 | -0.0555533 |
| HLA-B | major histocompatibility complex, class I, B | -0.0547715 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0520893 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0498483 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0494002 |
| MAP1B | microtubule-associated protein 1B | -0.048426 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0482282 |
| RPL19 | ribosomal protein L19 | -0.046573 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.044888 |
| RPL34 | ribosomal protein L34 | -0.0435911 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0431916 |
| RPLP0 | ribosomal protein, large, P0 | -0.0430375 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0422153 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0403185 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0399125 |
| GNAS | GNAS complex locus | -0.0395538 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0383417 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0380978 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0373473 |
| GOLGB1 | golgin B1 | -0.037236 |
| RPS24 | ribosomal protein S24 | -0.0370454 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0367108 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0366826 |
| RPS23 | ribosomal protein S23 | -0.03577 |
| RPS25 | ribosomal protein S25 | -0.0353951 |
| S100A10 | S100 calcium binding protein A10 | -0.0338452 |
| DSG2 | desmoglein 2 | -0.0332822 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0330841 |
| RPS29 | ribosomal protein S29 | -0.0326041 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0323742 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0315295 |
| TJP1 | tight junction protein 1 | -0.0313296 |
| HM13 | histocompatibility (minor) 13 | -0.0308729 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0306148 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0305892 |
| RPL8 | ribosomal protein L8 | -0.0303553 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0295208 |
| RPL23 | ribosomal protein L23 | -0.0292875 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0292538 |
| RPS8 | ribosomal protein S8 | -0.0292211 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0287645 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0286655 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0286246 |
| STC1 | stanniocalcin 1 | -0.0279075 |
| RPL11 | ribosomal protein L11 | -0.0274044 |
| MYO1E | myosin IE | -0.0273573 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.02733 |
| CLTC | clathrin, heavy chain (Hc) | -0.0270655 |
| PKM | pyruvate kinase, muscle | -0.0269398 |
| IER3 | immediate early response 3 | -0.0267985 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0265471 |
| MXD1 | MAX dimerization protein 1 | -0.0262731 |
| TRAM1 | translocation associated membrane protein 1 | -0.0259026 |
| AGR2 | anterior gradient 2 | -0.0258814 |
| ANXA2 | annexin A2 | -0.0256857 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0252097 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0250776 |
| RPS13 | ribosomal protein S13 | -0.024999 |
| MYADM | myeloid-associated differentiation marker | -0.0248565 |
| LCN2 | lipocalin 2 | -0.0248347 |
| EGR1 | early growth response 1 | -0.0247853 |
| LDHA | lactate dehydrogenase A | -0.0246535 |
| RPLP1 | ribosomal protein, large, P1 | -0.0245858 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0244915 |
| PFN1 | profilin 1 | -0.023927 |
| IGF2 | insulin-like growth factor 2 | -0.023587 |
| RPS14 | ribosomal protein S14 | -0.0229285 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.022747 |
| PLAU | plasminogen activator, urokinase | -0.0227013 |
| TPM4 | tropomyosin 4 | -0.0226179 |
| COG5 | component of oligomeric golgi complex 5 | -0.0224162 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0221534 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0219831 |
| RPL28 | ribosomal protein L28 | -0.0217937 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.0215926 |
| INTS6 | integrator complex subunit 6 | -0.0213202 |
| PCNX4 | pecanex 4 | -0.0211712 |
| TMEM123 | transmembrane protein 123 | -0.0211149 |
| CD68 | CD68 molecule | -0.0211123 |
| LAMA4 | laminin, alpha 4 | -0.0210726 |
| RPL9 | ribosomal protein L9 | -0.020928 |
| RPS11 | ribosomal protein S11 | -0.0208974 |
| RPS15 | ribosomal protein S15 | -0.0208742 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0208534 |
