| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivabradine (hydrochloride) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ivabradine (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.16653 |
| AHNAK | AHNAK nucleoprotein | 0.116097 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0998947 |
| ENO1 | enolase 1, (alpha) | 0.0973931 |
| POTEF | POTE ankyrin domain family, member F | 0.0881628 |
| MSN | moesin | 0.070943 |
| MCL1 | myeloid cell leukemia 1 | 0.0697196 |
| ITGA6 | integrin, alpha 6 | 0.0653597 |
| KRT17 | keratin 17, type I | 0.0579596 |
| MYOF | myoferlin | 0.0543289 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0531402 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0524473 |
| TPM3 | tropomyosin 3 | 0.0512936 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0507336 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0499867 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0491523 |
| RPL3 | ribosomal protein L3 | 0.0481383 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0471833 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0470371 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0441123 |
| ASPH | aspartate beta-hydroxylase | 0.0423147 |
| PLEC | plectin | 0.0421657 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0387117 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0385253 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0382231 |
| CAPRIN2 | caprin family member 2 | 0.0378143 |
| MYO10 | myosin X | 0.0372345 |
| LMO7 | LIM domain 7 | 0.0371833 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0370211 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0366353 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.035843 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0351813 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0351511 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0336137 |
| SULF1 | sulfatase 1 | 0.0328798 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0321181 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0315669 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0313519 |
| SET | SET nuclear proto-oncogene | 0.0303109 |
| MEF2A | myocyte enhancer factor 2A | 0.0298679 |
| PCBP2 | poly(rC) binding protein 2 | 0.0295048 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0294244 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0290124 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0283871 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0282722 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0281337 |
| KIAA1671 | KIAA1671 | 0.0280796 |
| UTRN | utrophin | 0.0276282 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0273088 |
| RAI14 | retinoic acid induced 14 | 0.027298 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0271321 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.026891 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0268625 |
| RPS3 | ribosomal protein S3 | 0.0266022 |
| SLK | STE20-like kinase | 0.0264591 |
| EZR | ezrin | 0.0261333 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0260424 |
| KRT14 | keratin 14, type I | 0.0259979 |
| DST | dystonin | 0.0256289 |
| PRELID2 | PRELI domain containing 2 | 0.0251247 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0250216 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0249379 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0249004 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0248912 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0248045 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0245977 |
| EFNA5 | ephrin-A5 | 0.0240052 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0239182 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0238218 |
| MTSS1 | metastasis suppressor 1 | 0.0237728 |
| DIAPH1 | diaphanous-related formin 1 | 0.0237417 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0236261 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0234583 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0230831 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0228312 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0227571 |
| YAP1 | Yes-associated protein 1 | 0.022739 |
| RNF217 | ring finger protein 217 | 0.0225461 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0224407 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0224226 |
| LAMC2 | laminin, gamma 2 | 0.0224187 |
| BLCAP | bladder cancer associated protein | 0.0224103 |
| RASA3 | RAS p21 protein activator 3 | 0.0223691 |
| RPS12 | ribosomal protein S12 | 0.0223218 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0223037 |
| LUZP1 | leucine zipper protein 1 | 0.0219304 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0218211 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.0217593 |
| DOK5 | docking protein 5 | 0.0217166 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0215414 |
| RBM26 | RNA binding motif protein 26 | 0.0213073 |
| AMOTL1 | angiomotin like 1 | 0.0212463 |
| RPL4 | ribosomal protein L4 | 0.021204 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.021066 |
| BCL2L1 | BCL2-like 1 | 0.0210108 |
| RAD51B | RAD51 paralog B | 0.0209854 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0209046 |
| ITGB4 | integrin, beta 4 | 0.0208789 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0206054 |
| C1D | C1D nuclear receptor corepressor | 0.0205973 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.228135 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.162678 |
| H1-0 | H1.0 linker histone | -0.0972641 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0969517 |
| IGF2 | insulin-like growth factor 2 | -0.0920903 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0906115 |
| CLU | clusterin | -0.0826298 |
| RPS21 | ribosomal protein S21 | -0.073341 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0584476 |
| CD44 | CD44 molecule (Indian blood group) | -0.0578093 |
| STC1 | stanniocalcin 1 | -0.0575364 |
| GNAS | GNAS complex locus | -0.0571279 |
| RPS6 | ribosomal protein S6 | -0.0562758 |
| S100A10 | S100 calcium binding protein A10 | -0.0507867 |
| RPS24 | ribosomal protein S24 | -0.050452 |
| HLA-B | major histocompatibility complex, class I, B | -0.0493164 |
| TMSB10 | thymosin beta 10 | -0.0480346 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0462352 |
| ARF1 | ADP-ribosylation factor 1 | -0.0456824 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0447679 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0447193 |
| EMP1 | epithelial membrane protein 1 | -0.0428057 |
| KIAA1217 | KIAA1217 | -0.0414112 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0409414 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0402818 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0395308 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0392163 |
| RPL35A | ribosomal protein L35a | -0.0363057 |
| RPLP0 | ribosomal protein, large, P0 | -0.0353078 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0348571 |
| IER3 | immediate early response 3 | -0.0348274 |
| OSMR | oncostatin M receptor | -0.0347444 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0340674 |
| SDCBP | syndecan binding protein (syntenin) | -0.0335427 |
| RPL8 | ribosomal protein L8 | -0.0335365 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0332391 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0331479 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0325351 |
| RPS25 | ribosomal protein S25 | -0.032531 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0324576 |
| S100A6 | S100 calcium binding protein A6 | -0.0316998 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0316273 |
| RPLP1 | ribosomal protein, large, P1 | -0.0315676 |
| RPL27A | ribosomal protein L27a | -0.0307096 |
| MORF4L2 | mortality factor 4 like 2 | -0.0306287 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0301157 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0298365 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0298242 |
| HMGB1 | high mobility group box 1 | -0.0293124 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0289857 |
| RPL34 | ribosomal protein L34 | -0.0284429 |
| PALLD | palladin, cytoskeletal associated protein | -0.0283772 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0282599 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0282239 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0281417 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0279484 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0277808 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0275867 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0275689 |
| RPL11 | ribosomal protein L11 | -0.0272476 |
| RPS13 | ribosomal protein S13 | -0.0271618 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0268381 |
| RPS8 | ribosomal protein S8 | -0.0267587 |
| YBX3 | Y box binding protein 3 | -0.0263855 |
| HLA-E | major histocompatibility complex, class I, E | -0.0263253 |
| TUBB | tubulin, beta class I | -0.0259276 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0258273 |
| LDHA | lactate dehydrogenase A | -0.025225 |
| IRF1 | interferon regulatory factor 1 | -0.0250212 |
| RPS23 | ribosomal protein S23 | -0.0248591 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0246748 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0243692 |
| FUS | FUS RNA binding protein | -0.02422 |
| RPLP2 | ribosomal protein, large, P2 | -0.0236434 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.023608 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0234266 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0232602 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0232327 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0230394 |
| TMEM123 | transmembrane protein 123 | -0.0229733 |
| S100A9 | S100 calcium binding protein A9 | -0.0229361 |
| PGK1 | phosphoglycerate kinase 1 | -0.0228043 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0227854 |
| S100A4 | S100 calcium binding protein A4 | -0.0226853 |
| UBC | ubiquitin C | -0.0226605 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0225976 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0225654 |
| WASF2 | WAS protein family, member 2 | -0.0224955 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0224003 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0221681 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.022117 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0216246 |
| ADIRF | adipogenesis regulatory factor | -0.0213432 |
| MT2A | metallothionein 2A | -0.0212716 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0211807 |
| VAMP3 | vesicle-associated membrane protein 3 | -0.0210503 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0209417 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0208929 |
| TRAM1 | translocation associated membrane protein 1 | -0.0208154 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.0207938 |
