| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivabradine (hydrochloride) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivabradine (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.256305 |
| VCL | vinculin | 0.110059 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.108557 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.103292 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0889623 |
| DST | dystonin | 0.0863947 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0862922 |
| FBL | fibrillarin | 0.0828749 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0800889 |
| EGFR | epidermal growth factor receptor | 0.073337 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0708833 |
| MCL1 | myeloid cell leukemia 1 | 0.0655717 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.063912 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0634246 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0581424 |
| SEPTIN9 | septin 9 | 0.0538794 |
| ACTN4 | actinin, alpha 4 | 0.0524308 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0523584 |
| ACTG1 | actin gamma 1 | 0.0495369 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0469835 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0461577 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0423607 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0404779 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0398741 |
| AHNAK | AHNAK nucleoprotein | 0.0374146 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0374085 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0374036 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0371209 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.036809 |
| TNS3 | tensin 3 | 0.0364688 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0357785 |
| TPM1 | tropomyosin 1 (alpha) | 0.0356378 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0350077 |
| HMGA2 | high mobility group AT-hook 2 | 0.0348021 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0334149 |
| SMAD3 | SMAD family member 3 | 0.03293 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0328572 |
| MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 0.0328475 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0324842 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0324269 |
| SMYD3 | SET and MYND domain containing 3 | 0.0306048 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0305241 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0301812 |
| MSN | moesin | 0.0301475 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0299907 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0299432 |
| EXOC4 | exocyst complex component 4 | 0.0296755 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0294643 |
| EFNA5 | ephrin-A5 | 0.0291522 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0290003 |
| ASPH | aspartate beta-hydroxylase | 0.0289742 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0289446 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0287738 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0286842 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0286435 |
| MYOF | myoferlin | 0.0284875 |
| EHBP1 | EH domain binding protein 1 | 0.0281845 |
| NHSL1 | NHS-like 1 | 0.027935 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0276272 |
| FHL2 | four and a half LIM domains 2 | 0.027473 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0274317 |
| RNF220 | ring finger protein 220 | 0.0272871 |
| CDK19 | cyclin-dependent kinase 19 | 0.0270259 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0269005 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0268348 |
| L1CAM | L1 cell adhesion molecule | 0.0268264 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0267849 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0266894 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0265581 |
| RAD51B | RAD51 paralog B | 0.0259934 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.02599 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0258246 |
| ANGPTL4 | angiopoietin-like 4 | 0.0256504 |
| RPL3 | ribosomal protein L3 | 0.0255851 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.025323 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0251895 |
| PHF14 | PHD finger protein 14 | 0.0251243 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.02512 |
| PTK2 | protein tyrosine kinase 2 | 0.0250902 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0250447 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | 0.0250179 |
| AFAP1 | actin filament associated protein 1 | 0.0245897 |
| RNF213 | ring finger protein 213 | 0.0244968 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0243356 |
| DNMBP | dynamin binding protein | 0.0242278 |
| WDR27 | WD repeat domain 27 | 0.0240968 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0239856 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0238643 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0238343 |
| ATXN1 | ataxin 1 | 0.0237239 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0235942 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0230666 |
| SATB2 | SATB homeobox 2 | 0.0229431 |
| POTEF | POTE ankyrin domain family, member F | 0.0228612 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0226176 |
| UTRN | utrophin | 0.0224489 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0222702 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0222419 |
| ATM | ATM serine/threonine kinase | 0.0221968 |
| RASAL2 | RAS protein activator like 2 | 0.0221803 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.272552 |
| RPS16 | ribosomal protein S16 | -0.223823 |
| VIM | vimentin | -0.138132 |
| TMSB10 | thymosin beta 10 | -0.0943915 |
| PTMA | prothymosin, alpha | -0.090635 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0905332 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0795409 |
| SPAG9 | sperm associated antigen 9 | -0.0703077 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0691429 |
| RPLP0 | ribosomal protein, large, P0 | -0.0674921 |
| MORF4L2 | mortality factor 4 like 2 | -0.059595 |
| TMEM123 | transmembrane protein 123 | -0.056812 |
| TXNRD1 | thioredoxin reductase 1 | -0.0563632 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0561813 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.055514 |
| RPL35A | ribosomal protein L35a | -0.0552823 |
| CANX | calnexin | -0.0546963 |
| H1-0 | H1.0 linker histone | -0.0533761 |
| WDR45B | WD repeat domain 45B | -0.0520567 |
| RPS24 | ribosomal protein S24 | -0.050491 |
| S100A6 | S100 calcium binding protein A6 | -0.0489183 |
| S100A10 | S100 calcium binding protein A10 | -0.0482453 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0480501 |
| SNX14 | sorting nexin 14 | -0.0469129 |
| FTL | ferritin, light polypeptide | -0.0465389 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0434616 |
| YBX1 | Y box binding protein 1 | -0.0427917 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.042669 |
| GOLGA4 | golgin A4 | -0.0422229 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0421424 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0420898 |
| UBC | ubiquitin C | -0.0416093 |
| RPL12 | ribosomal protein L12 | -0.0413613 |
| RPS5 | ribosomal protein S5 | -0.0408692 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0406852 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0396932 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0395872 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0394066 |
| RPLP1 | ribosomal protein, large, P1 | -0.0383457 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0378119 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0377983 |
| RLF | rearranged L-myc fusion | -0.0367472 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0362497 |
| USP3 | ubiquitin specific peptidase 3 | -0.0359822 |
| SEPTIN7 | septin 7 | -0.0357113 |
| TUBB | tubulin, beta class I | -0.033905 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0331745 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.032867 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0324924 |
| RPS25 | ribosomal protein S25 | -0.0324491 |
| RPS6 | ribosomal protein S6 | -0.0323893 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0321276 |
| NOP58 | NOP58 ribonucleoprotein | -0.0321222 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0313332 |
| RPLP2 | ribosomal protein, large, P2 | -0.0311817 |
| ANXA2 | annexin A2 | -0.0308449 |
| OGA | O-GlcNAcase | -0.0298909 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0298718 |
| IER3 | immediate early response 3 | -0.029871 |
| MATR3 | matrin 3 | -0.0295574 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0292894 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0286744 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0285841 |
| RPL8 | ribosomal protein L8 | -0.0283783 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0283674 |
| ANLN | anillin, actin binding protein | -0.0281661 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0271463 |
| HDLBP | high density lipoprotein binding protein | -0.0269949 |
| HMGA1 | high mobility group AT-hook 1 | -0.0268331 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0268291 |
| MT2A | metallothionein 2A | -0.0267394 |
| SUCO | SUN domain containing ossification factor | -0.0267344 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0266879 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0263086 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0261211 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0260409 |
| TAOK1 | TAO kinase 1 | -0.0260307 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0259815 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | -0.0258239 |
| RPL36A | ribosomal protein L36a | -0.0256245 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0255179 |
| HMGB1 | high mobility group box 1 | -0.0254358 |
| TPX2 | TPX2, microtubule-associated | -0.0254233 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0253376 |
| GNAS | GNAS complex locus | -0.0251312 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0250576 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0249858 |
| NPR2 | natriuretic peptide receptor 2 | -0.0249195 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0248069 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0247861 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0243062 |
| MED29 | mediator complex subunit 29 | -0.0242718 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0240242 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0239725 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0238862 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0238337 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0238241 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0235663 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0234402 |
| RBM39 | RNA binding motif protein 39 | -0.0233996 |
