| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivabradine (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivabradine (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.234903 |
| VCL | vinculin | 0.17733 |
| AHNAK | AHNAK nucleoprotein | 0.163037 |
| TMSB4X | thymosin beta 4, X-linked | 0.144755 |
| ACTG1 | actin gamma 1 | 0.143851 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.135905 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.122372 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.11318 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0926165 |
| TJP1 | tight junction protein 1 | 0.0908253 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0902675 |
| ENO1 | enolase 1, (alpha) | 0.0870088 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0848762 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0834775 |
| FOXP1 | forkhead box P1 | 0.0834332 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0793626 |
| POTEF | POTE ankyrin domain family, member F | 0.0765976 |
| EFNA5 | ephrin-A5 | 0.0726071 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0710653 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0708689 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0702536 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0678708 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0675152 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.062275 |
| NFIA | nuclear factor I/A | 0.0603135 |
| PCBP2 | poly(rC) binding protein 2 | 0.0597951 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0582036 |
| RPL3 | ribosomal protein L3 | 0.057946 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0565926 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0564911 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0553437 |
| APP | amyloid beta (A4) precursor protein | 0.0550129 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.052226 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0516519 |
| PRELID2 | PRELI domain containing 2 | 0.0515284 |
| RPL23 | ribosomal protein L23 | 0.0511072 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0498282 |
| CALR | calreticulin | 0.0485556 |
| SET | SET nuclear proto-oncogene | 0.0481126 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0469901 |
| RPL4 | ribosomal protein L4 | 0.0462642 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0462428 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0460664 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0457787 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.045725 |
| RPL37A | ribosomal protein L37a | 0.0445808 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0442116 |
| PDGFC | platelet derived growth factor C | 0.043984 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0437718 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0430985 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.042696 |
| NBEA | neurobeachin | 0.0422945 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0420643 |
| HDAC9 | histone deacetylase 9 | 0.041155 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0408439 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0403528 |
| SMYD3 | SET and MYND domain containing 3 | 0.0400593 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0400066 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0383257 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0377563 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0376926 |
| EVI5 | ecotropic viral integration site 5 | 0.037089 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0370222 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0369657 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0368013 |
| CANX | calnexin | 0.0367085 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0360109 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0359018 |
| CD47 | CD47 molecule | 0.0355542 |
| RBM39 | RNA binding motif protein 39 | 0.0354063 |
| TRERF1 | transcriptional regulating factor 1 | 0.0350679 |
| SBF2 | SET binding factor 2 | 0.0349616 |
| RPS27A | ribosomal protein S27a | 0.0346394 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 | 0.0341745 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0340255 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.0329449 |
| RPL13A | ribosomal protein L13a | 0.0324453 |
| RPS3 | ribosomal protein S3 | 0.0323994 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0320555 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0317772 |
| LDHA | lactate dehydrogenase A | 0.0307344 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0306879 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0306162 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.0305605 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0305477 |
| RPS12 | ribosomal protein S12 | 0.0301037 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | 0.0299649 |
| LOXL3 | lysyl oxidase-like 3 | 0.0292616 |
| YBX1 | Y box binding protein 1 | 0.0291743 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0288459 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0287082 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.028629 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0285152 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0284624 |
| COPA | coatomer protein complex, subunit alpha | 0.0282235 |
| PDE10A | phosphodiesterase 10A | 0.0281922 |
| GOLGA4 | golgin A4 | 0.0281744 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0279216 |
| RPS8 | ribosomal protein S8 | 0.0278183 |
| HDLBP | high density lipoprotein binding protein | 0.027714 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128065 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.067452 |
| CCND1 | cyclin D1 | -0.0471425 |
| RPS2 | ribosomal protein S2 | -0.0372481 |
| RTN4 | reticulon 4 | -0.0367871 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0366514 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0348879 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0320757 |
| BMP10 | bone morphogenetic protein 10 | -0.0284723 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0275686 |
| TXNRD1 | thioredoxin reductase 1 | -0.0273628 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0266682 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0266261 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0263749 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0260041 |
| RPS6 | ribosomal protein S6 | -0.024592 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0244799 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0227837 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0216112 |
| HMGA1 | high mobility group AT-hook 1 | -0.02079 |
| H1-4 | H1.4 linker histone, cluster member | -0.0204418 |
| UBC | ubiquitin C | -0.0185962 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0176676 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0174959 |
| IRS1 | insulin receptor substrate 1 | -0.0173034 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0172963 |
| SGMS2 | sphingomyelin synthase 2 | -0.0172823 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0172801 |
| COMMD10 | COMM domain containing 10 | -0.0168955 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0167337 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0167288 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0165848 |
| MRTFA | myocardin related transcription factor A | -0.0162627 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0160968 |
| S100A10 | S100 calcium binding protein A10 | -0.0156717 |
| CARS1 | cysteinyl-tRNA synthetase 1 | -0.0155826 |
| RPL38 | ribosomal protein L38 | -0.015578 |
| DIAPH3 | diaphanous-related formin 3 | -0.0154755 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0154409 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | -0.0153164 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.0151456 |
| ATN1 | atrophin 1 | -0.0151308 |
| MEF2A | myocyte enhancer factor 2A | -0.014967 |
| MFSD14A | major facilitator superfamily domain containing 14A | -0.0148827 |
| RPL21 | ribosomal protein L21 | -0.0148157 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0147467 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0146924 |
| RELA | v-rel avian reticuloendotheliosis viral oncogene homolog A | -0.0144136 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0142177 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0141668 |
| CENPE | centromere protein E, 312kDa | -0.0141326 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0140827 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0140348 |
| BRD2 | bromodomain containing 2 | -0.0137559 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0137058 |
| THBD | thrombomodulin | -0.0135234 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | -0.0133181 |
| BRD4 | bromodomain containing 4 | -0.0130617 |
| DIPK2A | divergent protein kinase domain 2A | -0.0129642 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0128855 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0127563 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0125246 |
| INO80 | INO80 complex subunit | -0.012511 |
| S100A11 | S100 calcium binding protein A11 | -0.0124332 |
| RPS15 | ribosomal protein S15 | -0.0122957 |
| KDM6B | lysine (K)-specific demethylase 6B | -0.0122119 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 | -0.012092 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.0120576 |
| HJURP | Holliday junction recognition protein | -0.0119788 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.011958 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | -0.0118831 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0118022 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0117585 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0117239 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0115923 |
| ZNF608 | zinc finger protein 608 | -0.0115793 |
| CLTC | clathrin, heavy chain (Hc) | -0.011504 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0114977 |
| C1ORF52 | chromosome 1 open reading frame 52 | -0.0113675 |
| LRRC58 | leucine rich repeat containing 58 | -0.0113503 |
| MT2A | metallothionein 2A | -0.0113359 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0112867 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0112778 |
| IPO11 | importin 11 | -0.0112505 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.011244 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0110762 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.011076 |
| RUNX1 | runt-related transcription factor 1 | -0.0110667 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | -0.0110644 |
| CWC27 | CWC27 spliceosome-associated protein homolog (S. cerevisiae) | -0.0109259 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0109182 |
| NUP98 | nucleoporin 98kDa | -0.0108957 |
| DHFR | dihydrofolate reductase | -0.0108288 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | -0.010799 |
| JAK1 | Janus kinase 1 | -0.0107683 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0105699 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | -0.0105675 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0105246 |
| RASAL2 | RAS protein activator like 2 | -0.0105193 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0105182 |
