| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivabradine (hydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivabradine (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.173203 |
| FN1 | fibronectin 1 | 0.113201 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.110472 |
| PLIN2 | perilipin 2 | 0.100395 |
| AHNAK | AHNAK nucleoprotein | 0.0994858 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0954134 |
| ENO1 | enolase 1, (alpha) | 0.0932984 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0930319 |
| PGK1 | phosphoglycerate kinase 1 | 0.090683 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0880089 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0837362 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0769108 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0653296 |
| VCAN | versican | 0.0620634 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0614177 |
| ACTG1 | actin gamma 1 | 0.0597318 |
| LDHA | lactate dehydrogenase A | 0.059488 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.057717 |
| C3 | complement component 3 | 0.055814 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0536464 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0525584 |
| RPL23 | ribosomal protein L23 | 0.0521917 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0514682 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0495876 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0489448 |
| RPS3 | ribosomal protein S3 | 0.0472403 |
| TMSB4X | thymosin beta 4, X-linked | 0.0456264 |
| YBX1 | Y box binding protein 1 | 0.0455746 |
| PTMA | prothymosin, alpha | 0.045265 |
| ANXA2 | annexin A2 | 0.04517 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0443228 |
| RNF213 | ring finger protein 213 | 0.0440632 |
| HLA-B | major histocompatibility complex, class I, B | 0.0440169 |
| CADM1 | cell adhesion molecule 1 | 0.0438575 |
| RPL4 | ribosomal protein L4 | 0.0431555 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.042806 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0425271 |
| TPM4 | tropomyosin 4 | 0.0419212 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0413263 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0397697 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0397084 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.038802 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0386847 |
| RPS12 | ribosomal protein S12 | 0.0370311 |
| CALR | calreticulin | 0.0366369 |
| RAI1 | retinoic acid induced 1 | 0.0363928 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0361369 |
| PCBP2 | poly(rC) binding protein 2 | 0.0360926 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0354961 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0352491 |
| COL1A2 | collagen, type I, alpha 2 | 0.0351906 |
| THBS2 | thrombospondin 2 | 0.0350207 |
| FBXO32 | F-box protein 32 | 0.033912 |
| SDC4 | syndecan 4 | 0.0332498 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0331364 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0330663 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0329536 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.032792 |
| RPS4X | ribosomal protein S4, X-linked | 0.0326997 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0318771 |
| FAM20C | family with sequence similarity 20, member C | 0.0309966 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0308932 |
| THBS1 | thrombospondin 1 | 0.0300833 |
| ZNF292 | zinc finger protein 292 | 0.0299959 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0296051 |
| ITM2B | integral membrane protein 2B | 0.0289231 |
| APP | amyloid beta (A4) precursor protein | 0.0287787 |
| B2M | beta-2-microglobulin | 0.0287031 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0282887 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0278297 |
| TXNIP | thioredoxin interacting protein | 0.0277804 |
| ADAR | adenosine deaminase, RNA-specific | 0.0272568 |
| FLNB | filamin B, beta | 0.027138 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0265454 |
| HLA-A | major histocompatibility complex, class I, A | 0.0261614 |
| RPL3 | ribosomal protein L3 | 0.0253305 |
| SQSTM1 | sequestosome 1 | 0.0250573 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0247653 |
| FTL | ferritin, light polypeptide | 0.0246391 |
| POTEF | POTE ankyrin domain family, member F | 0.0245343 |
| RPL37A | ribosomal protein L37a | 0.0240902 |
| RPS20 | ribosomal protein S20 | 0.0240685 |
| MXI1 | MAX interactor 1, dimerization protein | 0.023999 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0235962 |
| RPL35A | ribosomal protein L35a | 0.0233141 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0230732 |
| MMP2 | matrix metallopeptidase 2 | 0.0228525 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0227534 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0222812 |
| MCL1 | myeloid cell leukemia 1 | 0.0221365 |
| DENND5A | DENN/MADD domain containing 5A | 0.0220013 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0216963 |
| CDC27 | cell division cycle 27 | 0.0212538 |
| PRELID2 | PRELI domain containing 2 | 0.0208125 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0208081 |
| FOSL1 | FOS-like antigen 1 | 0.0207799 |
| LIMA1 | LIM domain and actin binding 1 | 0.0207139 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0207011 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0206461 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0205944 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.167441 |
| SPAG9 | sperm associated antigen 9 | -0.0898357 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0892116 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.088404 |
| CD44 | CD44 molecule (Indian blood group) | -0.0806345 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0802081 |
| NAV2 | neuron navigator 2 | -0.0794843 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0762836 |
| MSN | moesin | -0.0762452 |
| RPS6 | ribosomal protein S6 | -0.0748514 |
| VCL | vinculin | -0.0737566 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0722302 |
| RPS2 | ribosomal protein S2 | -0.0718089 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0703526 |
| FRMD4A | FERM domain containing 4A | -0.0687609 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0666771 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0654074 |
| HMGA2 | high mobility group AT-hook 2 | -0.063572 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0633347 |
| INTS6 | integrator complex subunit 6 | -0.0622879 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.062152 |
| CDH13 | cadherin 13 | -0.0605585 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0559742 |
| GPC6 | glypican 6 | -0.053757 |
| CLTC | clathrin, heavy chain (Hc) | -0.0529765 |
| BICC1 | BicC family RNA binding protein 1 | -0.0522504 |
| KYNU | kynureninase | -0.0510723 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0489977 |
| NABP1 | nucleic acid binding protein 1 | -0.0484482 |
| MORF4L2 | mortality factor 4 like 2 | -0.04823 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0475654 |
| JMJD1C | jumonji domain containing 1C | -0.0469841 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0469637 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0464449 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0456316 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0444816 |
| PDE10A | phosphodiesterase 10A | -0.043855 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0436309 |
| NDRG1 | N-myc downstream regulated 1 | -0.0436018 |
| GLIS3 | GLIS family zinc finger 3 | -0.0433472 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0427377 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0424312 |
| IER3 | immediate early response 3 | -0.0416274 |
| GOLGA4 | golgin A4 | -0.0412227 |
| GOLGB1 | golgin B1 | -0.0408431 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.04058 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0390067 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0389871 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0384255 |
| STC1 | stanniocalcin 1 | -0.0376041 |
| TAOK1 | TAO kinase 1 | -0.0375227 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0373822 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0373605 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0373438 |
| RPS24 | ribosomal protein S24 | -0.0370402 |
| NAV1 | neuron navigator 1 | -0.0369008 |
| SNX9 | sorting nexin 9 | -0.0368783 |
| TMEM132D | transmembrane protein 132D | -0.0366929 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0366319 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0363358 |
| FNIP1 | folliculin interacting protein 1 | -0.0361744 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0360387 |
| SEPTIN9 | septin 9 | -0.0357974 |
| UBC | ubiquitin C | -0.0356772 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0353385 |
| SMYD3 | SET and MYND domain containing 3 | -0.0353336 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0351639 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0351371 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0350867 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0343876 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0342054 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0339061 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0338852 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.033713 |
| VMP1 | vacuole membrane protein 1 | -0.0331541 |
| RBM39 | RNA binding motif protein 39 | -0.033047 |
| RPL38 | ribosomal protein L38 | -0.0324641 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0323963 |
| FMN1 | formin 1 | -0.0323626 |
| FUS | FUS RNA binding protein | -0.0321801 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0320976 |
| TAPBP | TAP binding protein (tapasin) | -0.0315714 |
| EGFR | epidermal growth factor receptor | -0.0313983 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0310022 |
| PRKCA | protein kinase C, alpha | -0.0307947 |
| MAP1B | microtubule-associated protein 1B | -0.0307024 |
| CTSD | cathepsin D | -0.0306341 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0305529 |
| PALLD | palladin, cytoskeletal associated protein | -0.0302296 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0296698 |
| EFNA5 | ephrin-A5 | -0.0296616 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0295959 |
| FBXO11 | F-box protein 11 | -0.0294683 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0290501 |
| KLHL24 | kelch-like family member 24 | -0.0290175 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.028897 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0284146 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0279142 |
| ANO6 | anoctamin 6 | -0.0276887 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0276329 |
