| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOX | lysyl oxidase | 0.13427 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.119519 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.117163 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.114405 |
| LOXL2 | lysyl oxidase-like 2 | 0.10265 |
| PODXL | podocalyxin-like | 0.0986647 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0957818 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0875397 |
| APP | amyloid beta (A4) precursor protein | 0.082389 |
| FLNB | filamin B, beta | 0.0808623 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0774241 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.077098 |
| STC1 | stanniocalcin 1 | 0.0747837 |
| THBS2 | thrombospondin 2 | 0.0724539 |
| PLAT | plasminogen activator, tissue | 0.07236 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0696474 |
| FBN1 | fibrillin 1 | 0.0678549 |
| COL5A2 | collagen, type V, alpha 2 | 0.0663597 |
| CD44 | CD44 molecule (Indian blood group) | 0.0662651 |
| COL3A1 | collagen, type III, alpha 1 | 0.0624742 |
| COL5A1 | collagen, type V, alpha 1 | 0.0624629 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0602946 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.058068 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0564465 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0542003 |
| SEPTIN9 | septin 9 | 0.0521921 |
| FNIP1 | folliculin interacting protein 1 | 0.0521435 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0509814 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0508843 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0497067 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0495722 |
| SMYD3 | SET and MYND domain containing 3 | 0.0450649 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0444248 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0426156 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0417247 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0413662 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0398692 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0393944 |
| SP3 | Sp3 transcription factor | 0.0393034 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0380852 |
| EGFR | epidermal growth factor receptor | 0.0367051 |
| APAF1 | apoptotic peptidase activating factor 1 | 0.0364433 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0364171 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0362418 |
| ANO6 | anoctamin 6 | 0.0356931 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.035306 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0349292 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0346482 |
| LDHA | lactate dehydrogenase A | 0.0345617 |
| FNBP1 | formin binding protein 1 | 0.0337798 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0331492 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0326885 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0324252 |
| USP34 | ubiquitin specific peptidase 34 | 0.0324089 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0322763 |
| TPR | translocated promoter region, nuclear basket protein | 0.0322034 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0317851 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0317412 |
| DST | dystonin | 0.0315407 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0313427 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.031139 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0310672 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0309682 |
| AFDN | afadin, adherens junction formation factor | 0.0307949 |
| ZNF148 | zinc finger protein 148 | 0.0307503 |
| VMP1 | vacuole membrane protein 1 | 0.0305042 |
| PRELID2 | PRELI domain containing 2 | 0.0302692 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0302584 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0302119 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.030113 |
| NBAS | neuroblastoma amplified sequence | 0.0300557 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0299544 |
| ATP13A3 | ATPase type 13A3 | 0.0298147 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0297956 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0297756 |
| CTSB | cathepsin B | 0.0297696 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0296874 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0294563 |
| GLG1 | golgi glycoprotein 1 | 0.029206 |
| NOTCH2 | notch 2 | 0.028942 |
| RNF169 | ring finger protein 169 | 0.0288022 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0287081 |
| OGA | O-GlcNAcase | 0.0286131 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0280213 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0279136 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0278343 |
| SBF2 | SET binding factor 2 | 0.0277842 |
| RBM25 | RNA binding motif protein 25 | 0.0276456 |
| C1D | C1D nuclear receptor corepressor | 0.0275107 |
| SNX27 | sorting nexin family member 27 | 0.0266505 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0264074 |
| CANX | calnexin | 0.0262119 |
| EZR | ezrin | 0.0260698 |
| RASA2 | RAS p21 protein activator 2 | 0.0257869 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0254019 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0253414 |
| LAMB1 | laminin, beta 1 | 0.0249269 |
| TPM3 | tropomyosin 3 | 0.0249267 |
| GOLGA2 | golgin A2 | 0.0247998 |
| PFKP | phosphofructokinase, platelet | 0.0247608 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.185753 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.120525 |
| S100A10 | S100 calcium binding protein A10 | -0.107221 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105023 |
| MT2A | metallothionein 2A | -0.0664319 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0652691 |
| VIM | vimentin | -0.0636827 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0611266 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.059567 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0537398 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0498422 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0496525 |
| S100A6 | S100 calcium binding protein A6 | -0.0478667 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0476715 |
| PTMA | prothymosin, alpha | -0.0474297 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0458229 |
| FTL | ferritin, light polypeptide | -0.0457077 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0456331 |
| RPLP1 | ribosomal protein, large, P1 | -0.0435904 |
| RPL35A | ribosomal protein L35a | -0.0430336 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0429097 |
| RPS8 | ribosomal protein S8 | -0.0403236 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0372769 |
| FN1 | fibronectin 1 | -0.0365674 |
| RPL23 | ribosomal protein L23 | -0.0362526 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0359873 |
| LMNA | lamin A/C | -0.0353623 |
| RPS19 | ribosomal protein S19 | -0.035245 |
| CDH13 | cadherin 13 | -0.0350618 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0345822 |
| RPL28 | ribosomal protein L28 | -0.0339801 |
| TPM1 | tropomyosin 1 (alpha) | -0.0339739 |
| B2M | beta-2-microglobulin | -0.0326104 |
| RPS6 | ribosomal protein S6 | -0.0324451 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0324418 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0322329 |
| RPL12 | ribosomal protein L12 | -0.0319442 |
| RPL36 | ribosomal protein L36 | -0.0316942 |
| PFN1 | profilin 1 | -0.0311102 |
| POTEF | POTE ankyrin domain family, member F | -0.0307411 |
| RACK1 | receptor for activated C kinase 1 | -0.0303289 |
| RPS14 | ribosomal protein S14 | -0.029781 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.029225 |
| RPLP2 | ribosomal protein, large, P2 | -0.0291917 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0290838 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0283993 |
| HLA-B | major histocompatibility complex, class I, B | -0.0283754 |
| SUCNR1 | succinate receptor 1 | -0.0283135 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.02764 |
| RPL19 | ribosomal protein L19 | -0.0275378 |
| SEC61G | Sec61 gamma subunit | -0.0267013 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.026367 |
| RPL35 | ribosomal protein L35 | -0.0256303 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0255209 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.025497 |
| RPL34 | ribosomal protein L34 | -0.0253998 |
| MEIS2 | Meis homeobox 2 | -0.0250766 |
| S100A11 | S100 calcium binding protein A11 | -0.0248184 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0244748 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0239322 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0234621 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0234471 |
| IL7R | interleukin 7 receptor | -0.0228768 |
| MED13L | mediator complex subunit 13-like | -0.0225644 |
| IRF1 | interferon regulatory factor 1 | -0.0225494 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0223934 |
| RPS27 | ribosomal protein S27 | -0.0219899 |
| MAP1B | microtubule-associated protein 1B | -0.0219419 |
| LRRC17 | leucine rich repeat containing 17 | -0.0215245 |
| CSTB | cystatin B (stefin B) | -0.0214226 |
| MX2 | MX dynamin-like GTPase 2 | -0.0212952 |
| S100A4 | S100 calcium binding protein A4 | -0.0211161 |
| RPS24 | ribosomal protein S24 | -0.020979 |
| RRBP1 | ribosome binding protein 1 | -0.0209779 |
| RPS27A | ribosomal protein S27a | -0.0209495 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0208894 |
| RPL37A | ribosomal protein L37a | -0.0205747 |
| IER3 | immediate early response 3 | -0.0205609 |
| SRPK2 | SRSF protein kinase 2 | -0.0204484 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0204346 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | -0.0203997 |
| RPL31 | ribosomal protein L31 | -0.0202841 |
| RPL27 | ribosomal protein L27 | -0.0201011 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0196061 |
| TENM3 | teneurin transmembrane protein 3 | -0.0194477 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.019406 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0191107 |
| S100A9 | S100 calcium binding protein A9 | -0.0190243 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0189414 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0189236 |
| AHNAK | AHNAK nucleoprotein | -0.0187197 |
| RPS21 | ribosomal protein S21 | -0.0186273 |
| RPS15 | ribosomal protein S15 | -0.0182051 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0181085 |
| KRT18 | keratin 18, type I | -0.0180685 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0177782 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.017776 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.0174834 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.017394 |
| RPS5 | ribosomal protein S5 | -0.017346 |
