| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSCAM | Down syndrome cell adhesion molecule | 0.0957593 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0765257 |
| MACC1 | metastasis associated in colon cancer 1 | 0.073642 |
| CCNL1 | cyclin L1 | 0.0682999 |
| STK24 | serine/threonine kinase 24 | 0.0548147 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0522269 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0510877 |
| NCKAP5 | NCK-associated protein 5 | 0.0486915 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0469451 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0463985 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.04469 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.044526 |
| MYO1E | myosin IE | 0.0421417 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0392509 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0387302 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0376445 |
| MEIS2 | Meis homeobox 2 | 0.0372074 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.036914 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0319561 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0315024 |
| TMEM51 | transmembrane protein 51 | 0.0312117 |
| TUFT1 | tuftelin 1 | 0.0302402 |
| VMP1 | vacuole membrane protein 1 | 0.0301743 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0300743 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0297391 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0295449 |
| COG6 | component of oligomeric golgi complex 6 | 0.0293027 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.029291 |
| OCLN | occludin | 0.0291496 |
| ALPK1 | alpha-kinase 1 | 0.0290766 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0285943 |
| PTEN | phosphatase and tensin homolog | 0.0285777 |
| RBM26 | RNA binding motif protein 26 | 0.0285738 |
| FOXP1 | forkhead box P1 | 0.0284402 |
| RBM39 | RNA binding motif protein 39 | 0.0282086 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0279932 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0279245 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0279011 |
| COPA | coatomer protein complex, subunit alpha | 0.0273344 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0272475 |
| EHF | ets homologous factor | 0.027064 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0266817 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | 0.0266239 |
| CENPF | centromere protein F, 350/400kDa | 0.0263962 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0253296 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.025057 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0249383 |
| TXNIP | thioredoxin interacting protein | 0.0249338 |
| WDR26 | WD repeat domain 26 | 0.0248464 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0247023 |
| TMEM62 | transmembrane protein 62 | 0.0243091 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | 0.0241354 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0239435 |
| ZNF638 | zinc finger protein 638 | 0.0237943 |
| PHF3 | PHD finger protein 3 | 0.0236782 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.02355 |
| ATXN1 | ataxin 1 | 0.0232568 |
| UBL3 | ubiquitin-like 3 | 0.0230459 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.022985 |
| LRRC1 | leucine rich repeat containing 1 | 0.0228713 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0226843 |
| MKI67 | marker of proliferation Ki-67 | 0.0225913 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0224875 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0224026 |
| TPCN1 | two pore segment channel 1 | 0.0223736 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0221647 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0220326 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | 0.0217905 |
| ETNK1 | ethanolamine kinase 1 | 0.0217652 |
| FHL2 | four and a half LIM domains 2 | 0.0217062 |
| OGA | O-GlcNAcase | 0.021506 |
| FOSL2 | FOS-like antigen 2 | 0.021428 |
| AOPEP | aminopeptidase O (putative) | 0.0213558 |
| SBF2 | SET binding factor 2 | 0.0211646 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0210457 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0210243 |
| CDHR2 | cadherin-related family member 2 | 0.020985 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0209218 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0208734 |
| RNF43 | ring finger protein 43 | 0.0202188 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.019999 |
| ATM | ATM serine/threonine kinase | 0.0198903 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0198356 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0197068 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0195387 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.0195066 |
| FNIP1 | folliculin interacting protein 1 | 0.0194673 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0193911 |
| YEATS2 | YEATS domain containing 2 | 0.0193362 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0192252 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0191246 |
| RNF149 | ring finger protein 149 | 0.0190952 |
| ATOSA | atos homolog A | 0.0189908 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0189733 |
| KLHL24 | kelch-like family member 24 | 0.0189327 |
| PDZD8 | PDZ domain containing 8 | 0.0188065 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0186955 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0186678 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0185582 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0184344 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.171115 |
| B2M | beta-2-microglobulin | -0.153552 |
| PTMA | prothymosin, alpha | -0.134654 |
| LCN2 | lipocalin 2 | -0.117114 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116896 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.111495 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.104835 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.103935 |
| LYZ | lysozyme | -0.103444 |
| HLA-B | major histocompatibility complex, class I, B | -0.0854764 |
| RNF213 | ring finger protein 213 | -0.0854252 |
| XAF1 | XIAP associated factor 1 | -0.0852157 |
| ANXA2 | annexin A2 | -0.0850306 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.081635 |
| SP100 | SP100 nuclear antigen | -0.0806405 |
| NPSR1 | neuropeptide S receptor 1 | -0.0801751 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.078372 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.073983 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0735111 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0733426 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0718604 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.071381 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.071142 |
| ACTG1 | actin gamma 1 | -0.0702861 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0688368 |
| FTL | ferritin, light polypeptide | -0.0678453 |
| PERP | PERP, TP53 apoptosis effector | -0.0676229 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0651902 |
| MX2 | MX dynamin-like GTPase 2 | -0.064795 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0625595 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0622412 |
| RPL35A | ribosomal protein L35a | -0.0619037 |
| RPL34 | ribosomal protein L34 | -0.0618477 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0613432 |
| INTS6 | integrator complex subunit 6 | -0.0609234 |
| TMSB10 | thymosin beta 10 | -0.0600729 |
| AREG | amphiregulin | -0.059833 |
| PLSCR2 | phospholipid scramblase 2 | -0.0595582 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0580812 |
| RPS6 | ribosomal protein S6 | -0.055615 |
| S100A6 | S100 calcium binding protein A6 | -0.0548655 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0542284 |
| RIGI | RNA sensor RIG-I | -0.0533776 |
| RPL23 | ribosomal protein L23 | -0.0533516 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0528683 |
| SQSTM1 | sequestosome 1 | -0.0528136 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.051223 |
| PKM | pyruvate kinase, muscle | -0.051023 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.05018 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0492505 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0491889 |
| RPS19 | ribosomal protein S19 | -0.0487044 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0456199 |
| IER3 | immediate early response 3 | -0.0446929 |
| RPLP1 | ribosomal protein, large, P1 | -0.0442454 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0439975 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0436422 |
| MT2A | metallothionein 2A | -0.0429812 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0421576 |
| RPL19 | ribosomal protein L19 | -0.0416763 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.041069 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0407612 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0398491 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0398436 |
| RPS8 | ribosomal protein S8 | -0.0394264 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0391771 |
| MX1 | MX dynamin-like GTPase 1 | -0.0383621 |
| PRKCA | protein kinase C, alpha | -0.0383491 |
| CUX1 | cut-like homeobox 1 | -0.0382507 |
| CST3 | cystatin C | -0.0379748 |
| ABLIM1 | actin binding LIM protein 1 | -0.0377374 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0377122 |
| HLA-C | major histocompatibility complex, class I, C | -0.0374881 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.036743 |
| RPL12 | ribosomal protein L12 | -0.0367349 |
| KRT18 | keratin 18, type I | -0.0366537 |
| KRT19 | keratin 19, type I | -0.0364048 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0363416 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0360805 |
| ENO1 | enolase 1, (alpha) | -0.0358213 |
| RPS24 | ribosomal protein S24 | -0.0357016 |
| ASPH | aspartate beta-hydroxylase | -0.0356659 |
| UBC | ubiquitin C | -0.034982 |
| S100A10 | S100 calcium binding protein A10 | -0.0348957 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0339445 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0337136 |
| HLA-E | major histocompatibility complex, class I, E | -0.0336662 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0334999 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0334601 |
| PGK1 | phosphoglycerate kinase 1 | -0.033194 |
| SSH2 | slingshot protein phosphatase 2 | -0.0331598 |
| HLA-A | major histocompatibility complex, class I, A | -0.0331112 |
| MSI2 | musashi RNA-binding protein 2 | -0.0330175 |
| PMP22 | peripheral myelin protein 22 | -0.0329915 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0329383 |
| MUC20 | mucin 20, cell surface associated | -0.0317641 |
| LAMA4 | laminin, alpha 4 | -0.0317629 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0316467 |
| EGR1 | early growth response 1 | -0.0313736 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0313292 |
