| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.255963 |
| IGF2 | insulin-like growth factor 2 | 0.159632 |
| C3 | complement component 3 | 0.141244 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0948959 |
| VEGFA | vascular endothelial growth factor A | 0.0514577 |
| RPL3 | ribosomal protein L3 | 0.0480364 |
| DSPP | dentin sialophosphoprotein | 0.0354993 |
| TNS1 | tensin 1 | 0.031354 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0261856 |
| POTEF | POTE ankyrin domain family, member F | 0.0250972 |
| TF | transferrin | 0.0248996 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.021494 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0208302 |
| CCNL1 | cyclin L1 | 0.0201612 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0200716 |
| GSE1 | Gse1 coiled-coil protein | 0.0195859 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0177044 |
| PCBP2 | poly(rC) binding protein 2 | 0.017676 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0171463 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0170281 |
| RPS18 | ribosomal protein S18 | 0.016648 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0165229 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0164294 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0159754 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0159399 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0158221 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0153546 |
| VMP1 | vacuole membrane protein 1 | 0.0149731 |
| SETD5 | SET domain containing 5 | 0.0147629 |
| MYO1B | myosin IB | 0.01398 |
| ZFP36 | ZFP36 ring finger protein | 0.0139667 |
| EGR1 | early growth response 1 | 0.0133916 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0128573 |
| DHFR | dihydrofolate reductase | 0.0128319 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.012779 |
| ATP13A3 | ATPase type 13A3 | 0.012487 |
| NUP58 | nucleoporin 58 | 0.0121516 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0119496 |
| BRD4 | bromodomain containing 4 | 0.0116739 |
| BAG6 | BCL2-associated athanogene 6 | 0.0116354 |
| DIAPH1 | diaphanous-related formin 1 | 0.0115844 |
| FAM120A | family with sequence similarity 120A | 0.0115156 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.011413 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.01139 |
| RPL21 | ribosomal protein L21 | 0.0112226 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0111419 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0110678 |
| MYO6 | myosin VI | 0.0108903 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0108682 |
| ATXN2L | ataxin 2-like | 0.0107747 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0107734 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0107544 |
| CRLS1 | cardiolipin synthase 1 | 0.0106925 |
| SON | SON DNA binding protein | 0.0105581 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | 0.0105273 |
| CUL3 | cullin 3 | 0.0105167 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0104718 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0103297 |
| KIF1B | kinesin family member 1B | 0.0103057 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0102657 |
| JAG1 | jagged 1 | 0.0102327 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0100777 |
| PRPF8 | pre-mRNA processing factor 8 | 0.00986561 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.00978061 |
| RPS7 | ribosomal protein S7 | 0.00965711 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.009612 |
| ATXN2 | ataxin 2 | 0.00948716 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.00947107 |
| TCIM | transcriptional and immune response regulator | 0.00941868 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00937882 |
| TPM3 | tropomyosin 3 | 0.00925911 |
| BRD2 | bromodomain containing 2 | 0.00925502 |
| FERMT2 | fermitin family member 2 | 0.00920749 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00915242 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.00913387 |
| MXRA7 | matrix-remodelling associated 7 | 0.00913114 |
| HDGF | hepatoma-derived growth factor | 0.00910513 |
| TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.00909692 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.009026 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00899106 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.00896227 |
| CDC7 | cell division cycle 7 | 0.00895149 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.00886177 |
| KIF26B | kinesin family member 26B | 0.00880739 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00878893 |
| PALLD | palladin, cytoskeletal associated protein | 0.00878381 |
| BEND7 | BEN domain containing 7 | 0.00865028 |
| GSPT1 | G1 to S phase transition 1 | 0.00860785 |
| FBRS | fibrosin | 0.00857912 |
| CHPF | chondroitin polymerizing factor | 0.00857471 |
| RPS4X | ribosomal protein S4, X-linked | 0.00854872 |
| COG6 | component of oligomeric golgi complex 6 | 0.00853339 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00852652 |
| GTPBP1 | GTP binding protein 1 | 0.00851727 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00851562 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.00847844 |
| TOM1 | target of myb1 (chicken) | 0.00841755 |
| TGOLN2 | trans-golgi network protein 2 | 0.00837456 |
| YAP1 | Yes-associated protein 1 | 0.00827798 |
| RPL29 | ribosomal protein L29 | 0.00826649 |
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | -0.157763 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.154365 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.151433 |
| GPC3 | glypican 3 | -0.145009 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0992498 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0946007 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0735227 |
| EHBP1 | EH domain binding protein 1 | -0.0701863 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0651139 |
| APOA2 | apolipoprotein A-II | -0.0632212 |
| RPS24 | ribosomal protein S24 | -0.0604741 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0598399 |
| MT2A | metallothionein 2A | -0.059597 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0586451 |
| RPS8 | ribosomal protein S8 | -0.057829 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0566116 |
| TRIM26 | tripartite motif containing 26 | -0.0551962 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0539809 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0530089 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0516355 |
| SDC4 | syndecan 4 | -0.0513469 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0513025 |
| RPS6 | ribosomal protein S6 | -0.051029 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0508188 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0506723 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.04989 |
| RPS27A | ribosomal protein S27a | -0.0482833 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0468559 |
| FN1 | fibronectin 1 | -0.0461211 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0457861 |
| FRMD5 | FERM domain containing 5 | -0.0440331 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0440035 |
| ENO1 | enolase 1, (alpha) | -0.0439719 |
| A2M | alpha-2-macroglobulin | -0.0432357 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0429113 |
| RPL37A | ribosomal protein L37a | -0.0403497 |
| RPLP1 | ribosomal protein, large, P1 | -0.0398848 |
| TMSB10 | thymosin beta 10 | -0.0388945 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0387679 |
| RPLP0 | ribosomal protein, large, P0 | -0.0385292 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0385147 |
| RRBP1 | ribosome binding protein 1 | -0.0382766 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0381113 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0375894 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0375167 |
| CANX | calnexin | -0.0374723 |
| KIAA1217 | KIAA1217 | -0.0357813 |
| RPL35A | ribosomal protein L35a | -0.0347083 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0344989 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0342625 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0336836 |
| RBM39 | RNA binding motif protein 39 | -0.0335482 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0334466 |
| IER3 | immediate early response 3 | -0.0331045 |
| RPL38 | ribosomal protein L38 | -0.033098 |
| RPL12 | ribosomal protein L12 | -0.0329489 |
| RPL11 | ribosomal protein L11 | -0.0324654 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0320995 |
| RPL34 | ribosomal protein L34 | -0.0320676 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0318579 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0315537 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0315158 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0312268 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0307812 |
| RPL31 | ribosomal protein L31 | -0.0306459 |
| ACTN4 | actinin, alpha 4 | -0.0305186 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0304622 |
| AHNAK | AHNAK nucleoprotein | -0.0302914 |
| ATP10A | ATPase, class V, type 10A | -0.0302174 |
| RPS21 | ribosomal protein S21 | -0.0302116 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0300352 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0299947 |
| PEG3 | paternally expressed 3 | -0.0296829 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.0295108 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0293486 |
| PGK1 | phosphoglycerate kinase 1 | -0.0292991 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0292919 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0290198 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | -0.0288911 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0287968 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0287943 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0286851 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0286123 |
| RPS11 | ribosomal protein S11 | -0.0281638 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0280816 |
| MALT1 | MALT1 paracaspase | -0.0279968 |
| TMEM123 | transmembrane protein 123 | -0.0279005 |
| RPS19 | ribosomal protein S19 | -0.0277559 |
| GNAS | GNAS complex locus | -0.0277037 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0274651 |
| RPL32 | ribosomal protein L32 | -0.0274594 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0274451 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0272767 |
| GPC6 | glypican 6 | -0.0272375 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0271983 |
| RPS13 | ribosomal protein S13 | -0.0271865 |
| ATXN1 | ataxin 1 | -0.0270469 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0270058 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0269595 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0269005 |
