| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.253369 |
| FLNB | filamin B, beta | 0.13197 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.110411 |
| PODXL | podocalyxin-like | 0.105082 |
| LMO7 | LIM domain 7 | 0.0969325 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0902204 |
| LDHA | lactate dehydrogenase A | 0.0858379 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.085489 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0794108 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.079011 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0743675 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0734394 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0719362 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0682179 |
| HM13 | histocompatibility (minor) 13 | 0.0674055 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0623606 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.062017 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0603855 |
| SULF1 | sulfatase 1 | 0.0602748 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0561401 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0557942 |
| INTS6 | integrator complex subunit 6 | 0.0551661 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0535413 |
| HLA-E | major histocompatibility complex, class I, E | 0.0511354 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0509533 |
| FOXO1 | forkhead box O1 | 0.0507708 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0499487 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0483712 |
| ENO1 | enolase 1, (alpha) | 0.0478924 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0463755 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.045933 |
| EGR1 | early growth response 1 | 0.0452059 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0449672 |
| HLA-B | major histocompatibility complex, class I, B | 0.0448031 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0427697 |
| FN1 | fibronectin 1 | 0.0420374 |
| MTSS1 | metastasis suppressor 1 | 0.0404072 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0400557 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0399696 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0397087 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0394703 |
| TNS3 | tensin 3 | 0.0390683 |
| ANXA1 | annexin A1 | 0.0385003 |
| SQLE | squalene epoxidase | 0.0376988 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0373754 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.0372028 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0362801 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0362288 |
| LAMA5 | laminin, alpha 5 | 0.0358345 |
| RASAL2 | RAS protein activator like 2 | 0.0357899 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0354146 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0353312 |
| MT1E | metallothionein 1E | 0.0352346 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0352012 |
| IGF2 | insulin-like growth factor 2 | 0.0348808 |
| FTL | ferritin, light polypeptide | 0.0344319 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0341026 |
| AMOTL1 | angiomotin like 1 | 0.0340751 |
| LAMC2 | laminin, gamma 2 | 0.0338838 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0337571 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0336079 |
| PCDH1 | protocadherin 1 | 0.0331333 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0330973 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0326322 |
| NAV2 | neuron navigator 2 | 0.0323391 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0322943 |
| SULF2 | sulfatase 2 | 0.0322037 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0317856 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.031351 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0312169 |
| CALB1 | calbindin 1, 28kDa | 0.0306634 |
| KIAA1671 | KIAA1671 | 0.0304911 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0301846 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0297963 |
| PLTP | phospholipid transfer protein | 0.0293452 |
| EMP1 | epithelial membrane protein 1 | 0.029261 |
| TJP1 | tight junction protein 1 | 0.0291692 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.0290869 |
| CD44 | CD44 molecule (Indian blood group) | 0.0287403 |
| PLEC | plectin | 0.0285039 |
| EZR | ezrin | 0.0284359 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0284347 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.0283255 |
| ITGB4 | integrin, beta 4 | 0.0283229 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.02791 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0279045 |
| DGKH | diacylglycerol kinase, eta | 0.0278789 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0278745 |
| STC1 | stanniocalcin 1 | 0.027654 |
| AOPEP | aminopeptidase O (putative) | 0.0276292 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0275902 |
| PLXNB2 | plexin B2 | 0.0274597 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0273473 |
| RPS13 | ribosomal protein S13 | 0.0273456 |
| FAM107B | family with sequence similarity 107, member B | 0.0272559 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0271793 |
| PLS3 | plastin 3 | 0.0270135 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0265006 |
| HLA-A | major histocompatibility complex, class I, A | 0.0264794 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0264612 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0804262 |
| RPS2 | ribosomal protein S2 | -0.0753625 |
| MYOF | myoferlin | -0.0728745 |
| TMSB4X | thymosin beta 4, X-linked | -0.0726638 |
| CLU | clusterin | -0.0711416 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0661677 |
| MEF2A | myocyte enhancer factor 2A | -0.0621572 |
| H1-0 | H1.0 linker histone | -0.0499593 |
| ASPH | aspartate beta-hydroxylase | -0.0466731 |
| CUL4B | cullin 4B | -0.0464025 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0444436 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0433437 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0424398 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0410497 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0382241 |
| CENPF | centromere protein F, 350/400kDa | -0.0361064 |
| ZNF292 | zinc finger protein 292 | -0.0359602 |
| RIN2 | Ras and Rab interactor 2 | -0.0358253 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0356309 |
| PTK2 | protein tyrosine kinase 2 | -0.0347898 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.034453 |
| NDRG1 | N-myc downstream regulated 1 | -0.0337033 |
| YBX3 | Y box binding protein 3 | -0.0330901 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0328342 |
| YBX1 | Y box binding protein 1 | -0.0324554 |
| SET | SET nuclear proto-oncogene | -0.031043 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0307552 |
| RPS21 | ribosomal protein S21 | -0.030495 |
| PRELID2 | PRELI domain containing 2 | -0.0298652 |
| NUP58 | nucleoporin 58 | -0.0298393 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0296063 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0290708 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.028692 |
| RPLP1 | ribosomal protein, large, P1 | -0.0286841 |
| RPL12 | ribosomal protein L12 | -0.0283125 |
| RLF | rearranged L-myc fusion | -0.0281192 |
| ANLN | anillin, actin binding protein | -0.0278929 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0277587 |
| AHNAK | AHNAK nucleoprotein | -0.0274552 |
| XPO1 | exportin 1 | -0.0269717 |
| RPL7 | ribosomal protein L7 | -0.0266371 |
| DSTN | destrin (actin depolymerizing factor) | -0.025976 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0254608 |
| SMAD3 | SMAD family member 3 | -0.0252496 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.025131 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0250948 |
| RPL35 | ribosomal protein L35 | -0.0246185 |
| TOP1 | topoisomerase (DNA) I | -0.024388 |
| FOXP1 | forkhead box P1 | -0.024378 |
| RPL8 | ribosomal protein L8 | -0.0242785 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0242177 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0239276 |
| MATR3 | matrin 3 | -0.0239072 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0236392 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0236276 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0234948 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0234739 |
| RPS12 | ribosomal protein S12 | -0.0234535 |
| NFIB | nuclear factor I/B | -0.023379 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0229479 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.022923 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0228012 |
| MT2A | metallothionein 2A | -0.0227768 |
| COG5 | component of oligomeric golgi complex 5 | -0.0227122 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0224566 |
| RPS6 | ribosomal protein S6 | -0.0224477 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0224245 |
| KIAA1217 | KIAA1217 | -0.0222971 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0222605 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0222588 |
| ARRDC3 | arrestin domain containing 3 | -0.0221564 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0219335 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0218326 |
| CANX | calnexin | -0.0217396 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0213509 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0213144 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0212957 |
| YAP1 | Yes-associated protein 1 | -0.0212888 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0211428 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0210851 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0210781 |
| RPL5 | ribosomal protein L5 | -0.0210609 |
| TPX2 | TPX2, microtubule-associated | -0.0208435 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0208393 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0207872 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0207799 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0207484 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0206742 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.0204029 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0202234 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0201954 |
| FAM13A | family with sequence similarity 13, member A | -0.0201923 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0201852 |
| GOLGA4 | golgin A4 | -0.0201746 |
| CKAP2 | cytoskeleton associated protein 2 | -0.020124 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0200999 |
| TPM3 | tropomyosin 3 | -0.0199398 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.0196989 |
| TXNRD1 | thioredoxin reductase 1 | -0.0195964 |
| PNN | pinin, desmosome associated protein | -0.0193171 |
