| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.111921 |
| GOLGA4 | golgin A4 | 0.101939 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0903549 |
| NDRG1 | N-myc downstream regulated 1 | 0.0843032 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0832669 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0732947 |
| TXNIP | thioredoxin interacting protein | 0.0721227 |
| DSPP | dentin sialophosphoprotein | 0.0701916 |
| LMO7 | LIM domain 7 | 0.0696766 |
| PTEN | phosphatase and tensin homolog | 0.0686785 |
| LDHA | lactate dehydrogenase A | 0.0675806 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0674165 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0669613 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0643116 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0641664 |
| EZR | ezrin | 0.0589156 |
| RNF43 | ring finger protein 43 | 0.0577846 |
| EREG | epiregulin | 0.056959 |
| PKM | pyruvate kinase, muscle | 0.0555827 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0555127 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0549772 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0526653 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0521177 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0509278 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.050368 |
| ATXN1 | ataxin 1 | 0.0502923 |
| ITGA6 | integrin, alpha 6 | 0.0495359 |
| MED13L | mediator complex subunit 13-like | 0.0485652 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0481603 |
| FAM13A | family with sequence similarity 13, member A | 0.0481206 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0478639 |
| VEGFA | vascular endothelial growth factor A | 0.0474572 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0466648 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0458734 |
| TNS4 | tensin 4 | 0.0452792 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0449311 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0443441 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0443305 |
| ABHD2 | abhydrolase domain containing 2 | 0.0435949 |
| NEBL | nebulette | 0.0434025 |
| USP34 | ubiquitin specific peptidase 34 | 0.0433602 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0432972 |
| OGA | O-GlcNAcase | 0.042814 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0419139 |
| RBM39 | RNA binding motif protein 39 | 0.0408727 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0408294 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0396719 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0393017 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0390295 |
| SETD5 | SET domain containing 5 | 0.0390068 |
| NF1 | neurofibromin 1 | 0.0387853 |
| KIF5B | kinesin family member 5B | 0.0383124 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.037958 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0376874 |
| VMP1 | vacuole membrane protein 1 | 0.0376368 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0376293 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0374745 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0373878 |
| TXNRD1 | thioredoxin reductase 1 | 0.0373277 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0371097 |
| TPD52 | tumor protein D52 | 0.0370602 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0370535 |
| TRIM2 | tripartite motif containing 2 | 0.0368751 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0368572 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0365358 |
| AREG | amphiregulin | 0.0364455 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0364302 |
| ZNF292 | zinc finger protein 292 | 0.0362866 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0362787 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0362593 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0359386 |
| MED13 | mediator complex subunit 13 | 0.0356918 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0350751 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0350121 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0350083 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0346171 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0342377 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0341078 |
| SSR1 | signal sequence receptor, alpha | 0.034029 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0338228 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.033467 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0332187 |
| USP6NL | USP6 N-terminal like | 0.033131 |
| HELZ | helicase with zinc finger | 0.0330108 |
| CDK19 | cyclin-dependent kinase 19 | 0.03291 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0324617 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0322578 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0321295 |
| RNF145 | ring finger protein 145 | 0.0320339 |
| NFIA | nuclear factor I/A | 0.0319174 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0316461 |
| TMF1 | TATA element modulatory factor 1 | 0.0314756 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0314377 |
| ZNF654 | zinc finger protein 654 | 0.0314262 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0312273 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.03071 |
| SNX13 | sorting nexin 13 | 0.0307054 |
| SBF2 | SET binding factor 2 | 0.0306805 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.03041 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0303039 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.202853 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.138805 |
| PTMA | prothymosin, alpha | -0.119076 |
| TMSB10 | thymosin beta 10 | -0.109202 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.10681 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0960428 |
| VCL | vinculin | -0.0795934 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0771149 |
| AHNAK | AHNAK nucleoprotein | -0.0603701 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0563002 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0546667 |
| RPLP1 | ribosomal protein, large, P1 | -0.052706 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0502376 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0495909 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0467895 |
| ACTG1 | actin gamma 1 | -0.0431991 |
| FHIT | fragile histidine triad | -0.0431333 |
| RPL35A | ribosomal protein L35a | -0.0414227 |
| RPS6 | ribosomal protein S6 | -0.0405215 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0395661 |
| RPS8 | ribosomal protein S8 | -0.0390849 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0375795 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0374668 |
| RPL23 | ribosomal protein L23 | -0.0366528 |
| LAMA4 | laminin, alpha 4 | -0.0358905 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0352556 |
| EGFR | epidermal growth factor receptor | -0.0348384 |
| ONECUT3 | one cut homeobox 3 | -0.0342257 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0338068 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0337699 |
| RNF217 | ring finger protein 217 | -0.0329158 |
| RAD51B | RAD51 paralog B | -0.0325624 |
| RPS19 | ribosomal protein S19 | -0.0323378 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0307461 |
| RPL37A | ribosomal protein L37a | -0.0300271 |
| IER3 | immediate early response 3 | -0.0296743 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0293068 |
| RPL36 | ribosomal protein L36 | -0.0291439 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0282309 |
| RPL34 | ribosomal protein L34 | -0.027428 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0272632 |
| RPL9 | ribosomal protein L9 | -0.0261088 |
| HMGB1 | high mobility group box 1 | -0.0260883 |
| LSAMP | limbic system-associated membrane protein | -0.0259519 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0253632 |
| EXOC4 | exocyst complex component 4 | -0.0248765 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0248316 |
| NRXN3 | neurexin 3 | -0.0242304 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.024161 |
| PCDH9 | protocadherin 9 | -0.0238285 |
| DENND1A | DENN/MADD domain containing 1A | -0.0237049 |
| RPS12 | ribosomal protein S12 | -0.0225158 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0224458 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.022036 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0218077 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0217544 |
| RPS20 | ribosomal protein S20 | -0.0216201 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0212468 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0210595 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0209933 |
| RPL31 | ribosomal protein L31 | -0.0208313 |
| POF1B | premature ovarian failure, 1B | -0.0208108 |
| TUBB | tubulin, beta class I | -0.0197441 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0195302 |
| RPS27A | ribosomal protein S27a | -0.019236 |
| RPS2 | ribosomal protein S2 | -0.0187468 |
| MTAP | methylthioadenosine phosphorylase | -0.0186037 |
| POU2F1 | POU class 2 homeobox 1 | -0.0184477 |
| RPS24 | ribosomal protein S24 | -0.0183027 |
| CCND1 | cyclin D1 | -0.0182322 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0180733 |
| CFAP44 | cilia and flagella associated protein 44 | -0.0180286 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0180083 |
| KRT18 | keratin 18, type I | -0.0180052 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0179085 |
| DIAPH3 | diaphanous-related formin 3 | -0.0179037 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0176501 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0175056 |
| WWOX | WW domain containing oxidoreductase | -0.0173902 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0173198 |
| RPS27 | ribosomal protein S27 | -0.017292 |
| GPR39 | G protein-coupled receptor 39 | -0.0171434 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0171305 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0169612 |
| VCAN | versican | -0.016876 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0166847 |
| S100A6 | S100 calcium binding protein A6 | -0.0165132 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0163593 |
| AGR2 | anterior gradient 2 | -0.0163422 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0163145 |
| ECT2 | epithelial cell transforming 2 | -0.0163086 |
| RPL27 | ribosomal protein L27 | -0.016296 |
| YBX1 | Y box binding protein 1 | -0.0162491 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0161612 |
| RPL28 | ribosomal protein L28 | -0.0160351 |
| RIN2 | Ras and Rab interactor 2 | -0.0157898 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0156401 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0155789 |
| MYO1D | myosin ID | -0.0155474 |
| RPL37 | ribosomal protein L37 | -0.0155094 |
