| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0996206 |
| VIM | vimentin | 0.0797944 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0630549 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0594403 |
| POTEF | POTE ankyrin domain family, member F | 0.0591512 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0575679 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0562244 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0513886 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0506697 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0485084 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0479521 |
| EPHA4 | EPH receptor A4 | 0.0470427 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0466311 |
| TNS3 | tensin 3 | 0.0457828 |
| CD44 | CD44 molecule (Indian blood group) | 0.0443711 |
| LDHA | lactate dehydrogenase A | 0.0431939 |
| EFNA5 | ephrin-A5 | 0.0428829 |
| EHBP1 | EH domain binding protein 1 | 0.042431 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.037411 |
| RPS4X | ribosomal protein S4, X-linked | 0.0343501 |
| APP | amyloid beta (A4) precursor protein | 0.0337586 |
| RNF213 | ring finger protein 213 | 0.0333726 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0317596 |
| TMSB10 | thymosin beta 10 | 0.0313872 |
| RIGI | RNA sensor RIG-I | 0.030983 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0307269 |
| CADM2 | cell adhesion molecule 2 | 0.03063 |
| EGR1 | early growth response 1 | 0.0301835 |
| HDAC9 | histone deacetylase 9 | 0.0284924 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0281615 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.025987 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0258603 |
| RAD51B | RAD51 paralog B | 0.0257669 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0253196 |
| PLK2 | polo-like kinase 2 | 0.0252168 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0251311 |
| CFAP299 | cilia and flagella associated protein 299 | 0.0250826 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.02488 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0246563 |
| RUNX1 | runt-related transcription factor 1 | 0.0241356 |
| ITGB4 | integrin, beta 4 | 0.0238847 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0235474 |
| TP63 | tumor protein p63 | 0.0235359 |
| MYOF | myoferlin | 0.022524 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0223318 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.022068 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0220468 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0218116 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0215888 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0211915 |
| JUN | jun proto-oncogene | 0.0211579 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0208953 |
| EGFR | epidermal growth factor receptor | 0.0208233 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0208057 |
| DNER | delta/notch-like EGF repeat containing | 0.0207893 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0207793 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0206228 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0203994 |
| PKM | pyruvate kinase, muscle | 0.020046 |
| EXOC4 | exocyst complex component 4 | 0.0199583 |
| TMEM123 | transmembrane protein 123 | 0.0195122 |
| SP100 | SP100 nuclear antigen | 0.0194415 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0190303 |
| PODXL | podocalyxin-like | 0.0188182 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0186886 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0185879 |
| FNBP4 | formin binding protein 4 | 0.018568 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.018374 |
| HMGA1 | high mobility group AT-hook 1 | 0.0179891 |
| UBAP2L | ubiquitin associated protein 2-like | 0.01788 |
| ENO1 | enolase 1, (alpha) | 0.0178419 |
| WDR27 | WD repeat domain 27 | 0.0174597 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0173773 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0173032 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0171228 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.0166898 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.016659 |
| LRRC49 | leucine rich repeat containing 49 | 0.0166303 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0162768 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0160491 |
| MTCL1 | microtubule crosslinking factor 1 | 0.016044 |
| DENND1A | DENN/MADD domain containing 1A | 0.0158673 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0152877 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0150707 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0149831 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0149481 |
| PLIN2 | perilipin 2 | 0.0148448 |
| CALR | calreticulin | 0.0146673 |
| PTK2 | protein tyrosine kinase 2 | 0.0144264 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0141596 |
| SSR1 | signal sequence receptor, alpha | 0.01404 |
| RPS3 | ribosomal protein S3 | 0.013735 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0136772 |
| ZNF638 | zinc finger protein 638 | 0.0133156 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0132857 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0130211 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0128283 |
| PMP22 | peripheral myelin protein 22 | 0.0127326 |
| LYST | lysosomal trafficking regulator | 0.0127317 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0127223 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.249719 |
| MT2A | metallothionein 2A | -0.179939 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.132082 |
| TXNRD1 | thioredoxin reductase 1 | -0.0903929 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.07089 |
| MT1X | metallothionein 1X | -0.0553588 |
| RPS2 | ribosomal protein S2 | -0.0539528 |
| SPAG9 | sperm associated antigen 9 | -0.0511314 |
| MT1E | metallothionein 1E | -0.0490069 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.047217 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0463772 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0456088 |
| EMP1 | epithelial membrane protein 1 | -0.0454864 |
| USP34 | ubiquitin specific peptidase 34 | -0.0446082 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0445167 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.04224 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0416105 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0382966 |
| UBC | ubiquitin C | -0.0377189 |
| RPS8 | ribosomal protein S8 | -0.0376801 |
| EREG | epiregulin | -0.0370016 |
| RPS6 | ribosomal protein S6 | -0.0336743 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0325928 |
| TMEM41B | transmembrane protein 41B | -0.0321994 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0321047 |
| CDCP1 | CUB domain containing protein 1 | -0.0320043 |
| CAPRIN2 | caprin family member 2 | -0.0319503 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0318219 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0315833 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.030669 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0305782 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0301342 |
| CENPF | centromere protein F, 350/400kDa | -0.0300783 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0298708 |
| RTN4 | reticulon 4 | -0.0296944 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0296371 |
| RPL38 | ribosomal protein L38 | -0.0292988 |
| SRGN | serglycin | -0.0291639 |
| YBX3 | Y box binding protein 3 | -0.0278145 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0277387 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0267795 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0260678 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0260236 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0258997 |
| S100A6 | S100 calcium binding protein A6 | -0.025314 |
| EZR | ezrin | -0.0246426 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0244984 |
| CLTC | clathrin, heavy chain (Hc) | -0.0244367 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0233294 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0229569 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0228528 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0227025 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0226433 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0223798 |
| XPO1 | exportin 1 | -0.0219137 |
| S100A10 | S100 calcium binding protein A10 | -0.0212796 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0212742 |
| RPL12 | ribosomal protein L12 | -0.0212233 |
| GOLT1B | golgi transport 1B | -0.0206324 |
| JMJD1C | jumonji domain containing 1C | -0.0204962 |
| USP12 | ubiquitin specific peptidase 12 | -0.0201436 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0200299 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0199081 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0198999 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0198399 |
| RRM2 | ribonucleotide reductase M2 | -0.0193636 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0192622 |
| SEPTIN7 | septin 7 | -0.0192061 |
| NCKAP1 | NCK-associated protein 1 | -0.0191972 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0191177 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.018913 |
| SNX14 | sorting nexin 14 | -0.0187565 |
| PRDX1 | peroxiredoxin 1 | -0.0185606 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0184004 |
| RECQL | RecQ helicase-like | -0.0183182 |
| NUP58 | nucleoporin 58 | -0.0183146 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0181254 |
| SRPK2 | SRSF protein kinase 2 | -0.0180258 |
| POM121 | POM121 transmembrane nucleoporin | -0.0179853 |
| RPL32 | ribosomal protein L32 | -0.0179488 |
| MKI67 | marker of proliferation Ki-67 | -0.0179248 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.0179179 |
| FERMT1 | fermitin family member 1 | -0.017911 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.017563 |
| RBM39 | RNA binding motif protein 39 | -0.0174956 |
| SDC4 | syndecan 4 | -0.0174732 |
| RPLP2 | ribosomal protein, large, P2 | -0.0174554 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.017356 |
| IL6ST | interleukin 6 signal transducer | -0.0172931 |
| RPS23 | ribosomal protein S23 | -0.0172861 |
| CEP170 | centrosomal protein 170kDa | -0.0172767 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0171542 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0171253 |
| RPLP0 | ribosomal protein, large, P0 | -0.0170956 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0169475 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0169243 |
| RPL7 | ribosomal protein L7 | -0.0168681 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0168053 |
| RPS12 | ribosomal protein S12 | -0.016557 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0163342 |
