| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.106062 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0708922 |
| ASPH | aspartate beta-hydroxylase | 0.0660845 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0530048 |
| INTS6 | integrator complex subunit 6 | 0.0347839 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0328172 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0321069 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0235403 |
| GRAMD1B | GRAM domain containing 1B | 0.0233452 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0227781 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0198718 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0196162 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0195154 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0192169 |
| HOMER1 | homer scaffolding protein 1 | 0.0187009 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0182043 |
| RPS3 | ribosomal protein S3 | 0.0181842 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.018013 |
| SCEL | sciellin | 0.0169492 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0162214 |
| MYOF | myoferlin | 0.0158636 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0157193 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.015713 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0156438 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0152768 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0150514 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0146294 |
| EFNA5 | ephrin-A5 | 0.0145581 |
| SMAD3 | SMAD family member 3 | 0.0143359 |
| SMYD3 | SET and MYND domain containing 3 | 0.0140812 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | 0.0132458 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0128186 |
| AHNAK | AHNAK nucleoprotein | 0.0127561 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0126759 |
| SLTM | SAFB-like, transcription modulator | 0.0120346 |
| FLNB | filamin B, beta | 0.0119218 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0117185 |
| RPL3 | ribosomal protein L3 | 0.0116991 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0116519 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0116107 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0112085 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0111945 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0111009 |
| SVIL | supervillin | 0.01106 |
| RNF213 | ring finger protein 213 | 0.0109597 |
| APP | amyloid beta (A4) precursor protein | 0.0107886 |
| MCU | mitochondrial calcium uniporter | 0.0107842 |
| RPS4X | ribosomal protein S4, X-linked | 0.0107538 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0106088 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0105868 |
| CMIP | c-Maf inducing protein | 0.0104706 |
| ANXA2 | annexin A2 | 0.010437 |
| CTBP2 | C-terminal binding protein 2 | 0.0103833 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0103498 |
| KRT86 | keratin 86, type II | 0.0101364 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00982516 |
| CUX1 | cut-like homeobox 1 | 0.00973164 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00969021 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.00957293 |
| LMO7 | LIM domain 7 | 0.0095266 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.00937235 |
| MIPOL1 | mirror-image polydactyly 1 | 0.00933337 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.00929585 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00920474 |
| DOCK5 | dedicator of cytokinesis 5 | 0.00906927 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0089467 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0089446 |
| PKM | pyruvate kinase, muscle | 0.00894325 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00883144 |
| RPLP1 | ribosomal protein, large, P1 | 0.00883037 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0088172 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.00875298 |
| MYO1E | myosin IE | 0.00865275 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00863454 |
| PTMA | prothymosin, alpha | 0.00861445 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00849558 |
| DSPP | dentin sialophosphoprotein | 0.00833848 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.00828794 |
| CCND1 | cyclin D1 | 0.00827247 |
| TNS3 | tensin 3 | 0.0080879 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0079737 |
| SP100 | SP100 nuclear antigen | 0.00795717 |
| PRKCA | protein kinase C, alpha | 0.00791346 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.00783524 |
| RPS7 | ribosomal protein S7 | 0.0077908 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0077895 |
| MYO5B | myosin VB | 0.00770184 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.00767494 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.00756423 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.00754888 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.00753466 |
| RASAL2 | RAS protein activator like 2 | 0.00750617 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.00734583 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00733606 |
| RPL37A | ribosomal protein L37a | 0.00732575 |
| VCL | vinculin | 0.00727776 |
| POTEF | POTE ankyrin domain family, member F | 0.00725437 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.00724779 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.00717988 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.00716519 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.203962 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.131927 |
| TXNRD1 | thioredoxin reductase 1 | -0.0926513 |
| NDRG1 | N-myc downstream regulated 1 | -0.05633 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0399854 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0338719 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0272191 |
| JMJD1C | jumonji domain containing 1C | -0.0271243 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0270144 |
| CES1 | carboxylesterase 1 | -0.026088 |
| OSMR | oncostatin M receptor | -0.0256701 |
| MT2A | metallothionein 2A | -0.0253165 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0236568 |
| UBC | ubiquitin C | -0.0231676 |
| EGR1 | early growth response 1 | -0.0226442 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0224894 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0218675 |
| LAMA4 | laminin, alpha 4 | -0.021699 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0213979 |
| SPAG9 | sperm associated antigen 9 | -0.020993 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0205519 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0203625 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0203369 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0202057 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0197548 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0196355 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0196346 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0181544 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0179169 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0178402 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0175545 |
| NGLY1 | N-glycanase 1 | -0.0174966 |
| CCNL1 | cyclin L1 | -0.0172918 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0169148 |
| TMSB10 | thymosin beta 10 | -0.0167795 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0166245 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0163707 |
| PATJ | PATJ crumbs cell polarity complex component | -0.016323 |
| SYAP1 | synapse associated protein 1 | -0.0162418 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0158935 |
| CCNI | cyclin I | -0.0158045 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.015769 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0157681 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0154219 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0149826 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | -0.0148501 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0143475 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0141442 |
| RTN4 | reticulon 4 | -0.0141151 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0139603 |
| RAB1A | RAB1A, member RAS oncogene family | -0.013897 |
| OGA | O-GlcNAcase | -0.0138644 |
| S100A10 | S100 calcium binding protein A10 | -0.0136625 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0134651 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0133562 |
| STC1 | stanniocalcin 1 | -0.0130763 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.013064 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0126877 |
| WDR45B | WD repeat domain 45B | -0.0124876 |
| RSF1 | remodeling and spacing factor 1 | -0.012418 |
| MGAT4C | MGAT4 family, member C | -0.0123476 |
| USP34 | ubiquitin specific peptidase 34 | -0.0123417 |
| TES | testin LIM domain protein | -0.0122637 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0121701 |
| AREG | amphiregulin | -0.0119329 |
| FNIP1 | folliculin interacting protein 1 | -0.0118124 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0117009 |
| NBEAL1 | neurobeachin-like 1 | -0.0115589 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0114341 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.011353 |
| MT1X | metallothionein 1X | -0.0113196 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0112931 |
| TMEM165 | transmembrane protein 165 | -0.011144 |
| TMEM87A | transmembrane protein 87A | -0.0109789 |
| PTEN | phosphatase and tensin homolog | -0.0109534 |
| YEATS2 | YEATS domain containing 2 | -0.0109207 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.010906 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0107593 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0107014 |
| SEPTIN2 | septin 2 | -0.010487 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0104453 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0104269 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0104239 |
| F11R | F11 receptor | -0.0103966 |
| B2M | beta-2-microglobulin | -0.0102566 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0102539 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0100833 |
| CPE | carboxypeptidase E | -0.0100527 |
| ZNF292 | zinc finger protein 292 | -0.0100495 |
| OFD1 | oral-facial-digital syndrome 1 | -0.0100237 |
| MCL1 | myeloid cell leukemia 1 | -0.00996659 |
| MYO1B | myosin IB | -0.00985278 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00966923 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | -0.0095794 |
| AFF4 | AF4/FMR2 family, member 4 | -0.00942174 |
| RUNX1 | runt-related transcription factor 1 | -0.00935953 |
| RBM25 | RNA binding motif protein 25 | -0.00935335 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.00934321 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.00933879 |
| RAP2B | RAP2B, member of RAS oncogene family | -0.00926536 |
