| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.126064 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.113392 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.111016 |
| EFNA5 | ephrin-A5 | 0.0948689 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0879273 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0825219 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0818239 |
| LOX | lysyl oxidase | 0.0817732 |
| STC1 | stanniocalcin 1 | 0.079243 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.073587 |
| NAV2 | neuron navigator 2 | 0.0717451 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0661602 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0645616 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0641388 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.062897 |
| USP34 | ubiquitin specific peptidase 34 | 0.0616882 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0605387 |
| FN1 | fibronectin 1 | 0.0603257 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0560027 |
| FAM20C | family with sequence similarity 20, member C | 0.0519629 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0507066 |
| LOXL2 | lysyl oxidase-like 2 | 0.047977 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0478966 |
| PRELID2 | PRELI domain containing 2 | 0.0478657 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0477322 |
| PCBP2 | poly(rC) binding protein 2 | 0.0474242 |
| RBM39 | RNA binding motif protein 39 | 0.0467766 |
| EXT1 | exostosin glycosyltransferase 1 | 0.045114 |
| ATXN1 | ataxin 1 | 0.0448349 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0438122 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0436997 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0436871 |
| ANXA2 | annexin A2 | 0.0425289 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0417351 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0413456 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0412987 |
| RUNX1 | runt-related transcription factor 1 | 0.040046 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0396878 |
| VIM | vimentin | 0.0394572 |
| SEC24A | SEC24 family member A | 0.0380925 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0373634 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0371237 |
| CA12 | carbonic anhydrase XII | 0.0370761 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0370356 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0368276 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0366392 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0361995 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0358186 |
| GOLGA4 | golgin A4 | 0.0351036 |
| ARF4 | ADP-ribosylation factor 4 | 0.0349961 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0346788 |
| VMP1 | vacuole membrane protein 1 | 0.0346259 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0334078 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0333255 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0332603 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0332579 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0332031 |
| NDRG1 | N-myc downstream regulated 1 | 0.0331168 |
| FAM107B | family with sequence similarity 107, member B | 0.0329717 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0323075 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0321949 |
| FAM13A | family with sequence similarity 13, member A | 0.0320074 |
| PARD3 | par-3 family cell polarity regulator | 0.0314692 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0314456 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0313882 |
| SMAD3 | SMAD family member 3 | 0.0312557 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0310761 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0310562 |
| PFKP | phosphofructokinase, platelet | 0.0304389 |
| JMJD1C | jumonji domain containing 1C | 0.0302016 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0299517 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0298073 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0295557 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0295219 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0294151 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0293916 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0293567 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0292767 |
| SSH2 | slingshot protein phosphatase 2 | 0.029211 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0292022 |
| HIP1 | huntingtin interacting protein 1 | 0.0290598 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0287743 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0286863 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0286595 |
| DST | dystonin | 0.028641 |
| CALU | calumenin | 0.028532 |
| ANXA1 | annexin A1 | 0.0281323 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0277908 |
| ARFGEF3 | ARFGEF family member 3 | 0.0276613 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0275548 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0271713 |
| UBC | ubiquitin C | 0.0269194 |
| FMNL2 | formin-like 2 | 0.0268758 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0267336 |
| RIOK3 | RIO kinase 3 | 0.0266371 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0265267 |
| NUMB | numb homolog (Drosophila) | 0.02652 |
| ANXA5 | annexin A5 | 0.0265109 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0264691 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0263414 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPLP1 | ribosomal protein, large, P1 | -0.0440171 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.043577 |
| FTL | ferritin, light polypeptide | -0.0397009 |
| YBX1 | Y box binding protein 1 | -0.0362689 |
| GLCCI1 | glucocorticoid induced 1 | -0.0319782 |
| NTN4 | netrin 4 | -0.0305275 |
| POTEF | POTE ankyrin domain family, member F | -0.0305046 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0303556 |
| TMSB10 | thymosin beta 10 | -0.029929 |
| RPS19 | ribosomal protein S19 | -0.0233679 |
| RPS3 | ribosomal protein S3 | -0.0208812 |
| KSR1 | kinase suppressor of ras 1 | -0.0205339 |
| USP3 | ubiquitin specific peptidase 3 | -0.0191318 |
| RPL3 | ribosomal protein L3 | -0.0183483 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0178085 |
| NRG1 | neuregulin 1 | -0.0172633 |
| RPS12 | ribosomal protein S12 | -0.0166255 |
| RPS17 | ribosomal protein S17 | -0.0165912 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0158443 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0157297 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0156526 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0155311 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0155249 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0152299 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0146007 |
| RPL4 | ribosomal protein L4 | -0.0140637 |
| NUP58 | nucleoporin 58 | -0.0137708 |
| RNF145 | ring finger protein 145 | -0.0135861 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0129848 |
| LDHB | lactate dehydrogenase B | -0.0129745 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0129015 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0127122 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0126352 |
| PTMA | prothymosin, alpha | -0.012563 |
| IL1R1 | interleukin 1 receptor, type I | -0.0123891 |
| PREPL | prolyl endopeptidase-like | -0.0121626 |
| VRK2 | vaccinia related kinase 2 | -0.0119113 |
| RPS2 | ribosomal protein S2 | -0.0118507 |
| DSTN | destrin (actin depolymerizing factor) | -0.0116571 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0116145 |
| RPL35 | ribosomal protein L35 | -0.0116119 |
| PFN1 | profilin 1 | -0.0114472 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0114295 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0114004 |
| RPL36 | ribosomal protein L36 | -0.0112449 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0110484 |
| MAX | MYC associated factor X | -0.0109672 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0109279 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0108558 |
| MEF2D | myocyte enhancer factor 2D | -0.0108296 |
| SET | SET nuclear proto-oncogene | -0.0107741 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.010682 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.010672 |
| BSG | basigin (Ok blood group) | -0.0106385 |
| NEFM | neurofilament, medium polypeptide | -0.0104063 |
| RPL27 | ribosomal protein L27 | -0.01038 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0102133 |
| RPL9 | ribosomal protein L9 | -0.0101877 |
| RPL23 | ribosomal protein L23 | -0.0101322 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -0.0100345 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0100043 |
| FAM162A | family with sequence similarity 162, member A | -0.00997202 |
| KYNU | kynureninase | -0.00982518 |
| ZNF12 | zinc finger protein 12 | -0.00977797 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.00968376 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.00950759 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00945704 |
| WDR43 | WD repeat domain 43 | -0.0094298 |
| RPS6 | ribosomal protein S6 | -0.0094177 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.00917647 |
| ANXA10 | annexin A10 | -0.00916045 |
| HMGB2 | high mobility group box 2 | -0.00912091 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | -0.00904852 |
| ANAPC1 | anaphase promoting complex subunit 1 | -0.00903423 |
| ROMO1 | reactive oxygen species modulator 1 | -0.00902317 |
| TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | -0.00892454 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.00891617 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | -0.00891554 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00887544 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.00886323 |
| RPS27 | ribosomal protein S27 | -0.00882738 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00875598 |
| SKP1 | S-phase kinase-associated protein 1 | -0.00875252 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.00872422 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.00869604 |
| CDK17 | cyclin-dependent kinase 17 | -0.00865712 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.00861602 |
| BRD8 | bromodomain containing 8 | -0.00857658 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | -0.00850828 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00850094 |
| CYB5R4 | cytochrome b5 reductase 4 | -0.00849449 |
| RPS9 | ribosomal protein S9 | -0.00847921 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00838881 |
| RPL13A | ribosomal protein L13a | -0.0083794 |
| HDGF | hepatoma-derived growth factor | -0.00836125 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | -0.00835327 |
| POU2F1 | POU class 2 homeobox 1 | -0.00823398 |
| TFG | TRK-fused gene | -0.00822369 |
| SELENOH | selenoprotein H | -0.00818887 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.00818492 |
