| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Ivermectin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.095538 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0933748 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0760199 |
| VIM | vimentin | 0.0724824 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0711676 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0694307 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0631993 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0577792 |
| FN1 | fibronectin 1 | 0.0560823 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.0518897 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0506659 |
| EXT1 | exostosin glycosyltransferase 1 | 0.04829 |
| OGA | O-GlcNAcase | 0.0472465 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0469963 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0468189 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0467634 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0463995 |
| PKM | pyruvate kinase, muscle | 0.0459582 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0456144 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0439667 |
| FTL | ferritin, light polypeptide | 0.0437388 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0428027 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0423621 |
| RPL12 | ribosomal protein L12 | 0.0421454 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.040928 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0404247 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0391273 |
| SPAG9 | sperm associated antigen 9 | 0.0369148 |
| HELZ | helicase with zinc finger | 0.03671 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.03666 |
| GOLGA4 | golgin A4 | 0.0364547 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0347249 |
| ENO1 | enolase 1, (alpha) | 0.0341897 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0340082 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0335988 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0335298 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0332301 |
| DTNA | dystrobrevin, alpha | 0.0327165 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.032589 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0323642 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0320141 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.031621 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0314549 |
| GNAS | GNAS complex locus | 0.0311618 |
| OSBP | oxysterol binding protein | 0.0309239 |
| ATP13A3 | ATPase type 13A3 | 0.0306139 |
| THOC2 | THO complex 2 | 0.0305832 |
| HLA-B | major histocompatibility complex, class I, B | 0.0305528 |
| RPS3 | ribosomal protein S3 | 0.0299166 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0299166 |
| FLNB | filamin B, beta | 0.0296355 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0292 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0291541 |
| CLTC | clathrin, heavy chain (Hc) | 0.029004 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0287462 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0287122 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0284675 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0280787 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0272254 |
| STC1 | stanniocalcin 1 | 0.0267168 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0267152 |
| CDC73 | cell division cycle 73 | 0.0265331 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0264814 |
| PHF21A | PHD finger protein 21A | 0.0264743 |
| SRP54 | signal recognition particle 54kDa | 0.0262019 |
| BRD2 | bromodomain containing 2 | 0.0258792 |
| RPS12 | ribosomal protein S12 | 0.0257506 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0257082 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0255853 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0255801 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0254744 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0254739 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0251077 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0249852 |
| AFAP1 | actin filament associated protein 1 | 0.0249101 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0247085 |
| ASPH | aspartate beta-hydroxylase | 0.0245638 |
| OLA1 | Obg-like ATPase 1 | 0.0243544 |
| SETD5 | SET domain containing 5 | 0.0243076 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.024279 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0242546 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0238406 |
| YBX1 | Y box binding protein 1 | 0.0236488 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0233926 |
| R3HDM1 | R3H domain containing 1 | 0.0232339 |
| RTN4 | reticulon 4 | 0.0232014 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0229765 |
| MT2A | metallothionein 2A | 0.0228967 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0221574 |
| CCNL1 | cyclin L1 | 0.0220553 |
| RBM39 | RNA binding motif protein 39 | 0.0219376 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0218383 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.021814 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0215356 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.021201 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.021166 |
| CSTB | cystatin B (stefin B) | 0.0210941 |
| GDNF | glial cell derived neurotrophic factor | 0.0209773 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0209397 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0208092 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.095603 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0796009 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0779492 |
| LMO7 | LIM domain 7 | -0.076782 |
| ATOSA | atos homolog A | -0.070698 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0649835 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0642574 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.057433 |
| SVIL | supervillin | -0.0568932 |
| ABHD17C | abhydrolase domain containing 17C | -0.0556782 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0525203 |
| TXNRD1 | thioredoxin reductase 1 | -0.05083 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0507129 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0500805 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0485558 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0466714 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0440184 |
| ANXA2 | annexin A2 | -0.043973 |
| LAMB3 | laminin, beta 3 | -0.0431688 |
| AHNAK | AHNAK nucleoprotein | -0.0423792 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0418131 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0417078 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0413287 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0407753 |
| MYO1E | myosin IE | -0.0402688 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0395019 |
| SNX9 | sorting nexin 9 | -0.0376988 |
| MUC16 | mucin 16, cell surface associated | -0.037409 |
| FAM107B | family with sequence similarity 107, member B | -0.0370289 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0364289 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0362008 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0351601 |
| MYO6 | myosin VI | -0.0340877 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0335715 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0333814 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0333771 |
| DENND1A | DENN/MADD domain containing 1A | -0.0333607 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0313429 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0309715 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0307679 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0302279 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0301853 |
| CEP350 | centrosomal protein 350kDa | -0.0301407 |
| IGF2 | insulin-like growth factor 2 | -0.0292705 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.029006 |
| EGFR | epidermal growth factor receptor | -0.0288302 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0287971 |
| FNBP1L | formin binding protein 1-like | -0.0287621 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0285628 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0284624 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.028123 |
| FOXP1 | forkhead box P1 | -0.0280141 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0280022 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0278012 |
| ATP11A | ATPase, class VI, type 11A | -0.0276005 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0274853 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0273855 |
| KRT17 | keratin 17, type I | -0.0271735 |
| STK17A | serine/threonine kinase 17a | -0.0271281 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0266607 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0263903 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0263266 |
| JUP | junction plakoglobin | -0.0263215 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0260986 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0260725 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.026047 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0260141 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0257512 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0256933 |
| TAOK3 | TAO kinase 3 | -0.0256919 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0253735 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0252961 |
| SLMAP | sarcolemma associated protein | -0.0249145 |
| EFNA5 | ephrin-A5 | -0.0249065 |
| PARD3 | par-3 family cell polarity regulator | -0.0246831 |
| SETX | senataxin | -0.0246743 |
| FDPS | farnesyl diphosphate synthase | -0.0246594 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0246333 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0245641 |
| OXSR1 | oxidative stress responsive 1 | -0.0245546 |
| NRG1 | neuregulin 1 | -0.0244963 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0243263 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0242605 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0240193 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0237505 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0235079 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0232506 |
| NPTN | neuroplastin | -0.0229797 |
| EZR | ezrin | -0.0229343 |
| CDYL | chromodomain protein, Y-like | -0.0229036 |
| LAMC2 | laminin, gamma 2 | -0.0227554 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.022581 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0225672 |
| TJP1 | tight junction protein 1 | -0.0225271 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0224773 |
| ACTN4 | actinin, alpha 4 | -0.0221224 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0220921 |
| MATR3 | matrin 3 | -0.0220195 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0216276 |
| CMIP | c-Maf inducing protein | -0.0214191 |
