| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Ivermectin perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Ivermectin_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.198173 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0958056 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0759155 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0700008 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0688513 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0679037 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.062465 |
| TPM3 | tropomyosin 3 | 0.0621178 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0600568 |
| POTEF | POTE ankyrin domain family, member F | 0.0599005 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0555658 |
| GRAMD1B | GRAM domain containing 1B | 0.050325 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0497406 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0497144 |
| PHIP | pleckstrin homology domain interacting protein | 0.048726 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.047812 |
| PKM | pyruvate kinase, muscle | 0.043637 |
| PCBP2 | poly(rC) binding protein 2 | 0.042582 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0418629 |
| RTN4 | reticulon 4 | 0.0417009 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0416869 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0411288 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0400746 |
| MSN | moesin | 0.0378195 |
| XPO1 | exportin 1 | 0.0374527 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0363428 |
| CCNL1 | cyclin L1 | 0.0354575 |
| PTK2 | protein tyrosine kinase 2 | 0.0353221 |
| EGR1 | early growth response 1 | 0.0335506 |
| NOTCH2 | notch 2 | 0.0331106 |
| SMAD3 | SMAD family member 3 | 0.0323162 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0318969 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0315663 |
| MED13L | mediator complex subunit 13-like | 0.0312591 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0296365 |
| MMP12 | matrix metallopeptidase 12 | 0.0295461 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0295074 |
| SRPK2 | SRSF protein kinase 2 | 0.0294935 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0291719 |
| BRD2 | bromodomain containing 2 | 0.0290963 |
| RASAL2 | RAS protein activator like 2 | 0.0286871 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0283612 |
| ZNF638 | zinc finger protein 638 | 0.0283604 |
| ATP11A | ATPase, class VI, type 11A | 0.0283392 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0283236 |
| PCNX1 | pecanex 1 | 0.0282234 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.028113 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0281114 |
| LATS2 | large tumor suppressor kinase 2 | 0.0279232 |
| YAP1 | Yes-associated protein 1 | 0.0278136 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0276968 |
| JMJD1C | jumonji domain containing 1C | 0.0276611 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0276187 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | 0.0272481 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0267114 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0266774 |
| NUP153 | nucleoporin 153kDa | 0.0264543 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0263166 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0262643 |
| MKI67 | marker of proliferation Ki-67 | 0.0260749 |
| USP34 | ubiquitin specific peptidase 34 | 0.0253932 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0252537 |
| SPAG9 | sperm associated antigen 9 | 0.0252283 |
| ANXA5 | annexin A5 | 0.0250146 |
| MEF2D | myocyte enhancer factor 2D | 0.0249116 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0248444 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0247913 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0246389 |
| COPA | coatomer protein complex, subunit alpha | 0.0243552 |
| PLCB4 | phospholipase C, beta 4 | 0.0243549 |
| NUP155 | nucleoporin 155kDa | 0.0239294 |
| CALD1 | caldesmon 1 | 0.0234457 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0233141 |
| NCKAP1 | NCK-associated protein 1 | 0.0232786 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0232397 |
| CENPF | centromere protein F, 350/400kDa | 0.023077 |
| MELK | maternal embryonic leucine zipper kinase | 0.0230288 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0229328 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0228613 |
| SIN3A | SIN3 transcription regulator family member A | 0.0228579 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0227744 |
| BBX | bobby sox homolog (Drosophila) | 0.0227513 |
| ATXN2 | ataxin 2 | 0.0227216 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0225746 |
| IGF2 | insulin-like growth factor 2 | 0.0224224 |
| IPO7 | importin 7 | 0.0223115 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0223079 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0222673 |
| DIS3L2 | DIS3 like 3'-5' exoribonuclease 2 | 0.0221275 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.022031 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0220188 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0219991 |
| FAM168A | family with sequence similarity 168, member A | 0.0219752 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0219729 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0217399 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0216737 |
| VMP1 | vacuole membrane protein 1 | 0.0216578 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0216553 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0216273 |
| ANO6 | anoctamin 6 | 0.0216239 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.259628 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.139903 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.128014 |
| TMSB10 | thymosin beta 10 | -0.124764 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0813963 |
| PTMA | prothymosin, alpha | -0.0726219 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0664009 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0639708 |
| RPL37A | ribosomal protein L37a | -0.060972 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0608519 |
| RPS8 | ribosomal protein S8 | -0.0572295 |
| VIM | vimentin | -0.0560317 |
| AEBP2 | AE binding protein 2 | -0.0516658 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0513816 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0512822 |
| VCL | vinculin | -0.0484979 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0484275 |
| RPL12 | ribosomal protein L12 | -0.0478546 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0472824 |
| YBX3 | Y box binding protein 3 | -0.046143 |
| RPL23 | ribosomal protein L23 | -0.045621 |
| RPLP1 | ribosomal protein, large, P1 | -0.0442239 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0438483 |
| RPL35A | ribosomal protein L35a | -0.0435622 |
| PDE10A | phosphodiesterase 10A | -0.0425834 |
| RPL37 | ribosomal protein L37 | -0.0406712 |
| RPL38 | ribosomal protein L38 | -0.0398988 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0394224 |
| HMGA2 | high mobility group AT-hook 2 | -0.0393657 |
| RPS19 | ribosomal protein S19 | -0.0383775 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0383124 |
| RPS27A | ribosomal protein S27a | -0.0382609 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0381563 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0369532 |
| RPL34 | ribosomal protein L34 | -0.0368848 |
| RPLP0 | ribosomal protein, large, P0 | -0.0368087 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.036805 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0360286 |
| RYR3 | ryanodine receptor 3 | -0.0356364 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0352241 |
| FBXO11 | F-box protein 11 | -0.0351734 |
| INTS6 | integrator complex subunit 6 | -0.0345167 |
| RPS24 | ribosomal protein S24 | -0.0343892 |
| RPS29 | ribosomal protein S29 | -0.0343159 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0335814 |
| RPS27 | ribosomal protein S27 | -0.0334674 |
| CANX | calnexin | -0.0333151 |
| RPS3 | ribosomal protein S3 | -0.032824 |
| RPL31 | ribosomal protein L31 | -0.0327029 |
| RPL36 | ribosomal protein L36 | -0.0323433 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.032303 |
| HLA-B | major histocompatibility complex, class I, B | -0.0321917 |
| RPS12 | ribosomal protein S12 | -0.0321737 |
| RACK1 | receptor for activated C kinase 1 | -0.0316005 |
| GNAS | GNAS complex locus | -0.03149 |
| RPL26 | ribosomal protein L26 | -0.0314258 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0313028 |
| AHNAK | AHNAK nucleoprotein | -0.0312489 |
| PRELID2 | PRELI domain containing 2 | -0.0307187 |
| WWOX | WW domain containing oxidoreductase | -0.0306089 |
| CAVIN1 | caveolae associated protein 1 | -0.030308 |
| RPS21 | ribosomal protein S21 | -0.0302645 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0302158 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0302105 |
| MT2A | metallothionein 2A | -0.0294463 |
| RPL19 | ribosomal protein L19 | -0.028896 |
| ATG7 | autophagy related 7 | -0.0284736 |
| OSMR | oncostatin M receptor | -0.0278516 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0277321 |
| RPL11 | ribosomal protein L11 | -0.0277259 |
| RPS6 | ribosomal protein S6 | -0.0274589 |
| RPLP2 | ribosomal protein, large, P2 | -0.0273314 |
| FMNL2 | formin-like 2 | -0.0265157 |
| S100A10 | S100 calcium binding protein A10 | -0.0264326 |
| RPL36A | ribosomal protein L36a | -0.0262132 |
| IER3 | immediate early response 3 | -0.0259835 |
| RPL5 | ribosomal protein L5 | -0.025912 |
| FTL | ferritin, light polypeptide | -0.0257961 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.025656 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0254558 |
| S100A6 | S100 calcium binding protein A6 | -0.0252033 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0251653 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0251437 |
| MORF4L2 | mortality factor 4 like 2 | -0.0249302 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0247216 |
| RPL7A | ribosomal protein L7a | -0.0247056 |
| MCL1 | myeloid cell leukemia 1 | -0.0242881 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.024085 |
| RPS15 | ribosomal protein S15 | -0.0231273 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0228891 |
| RPL30 | ribosomal protein L30 | -0.0227708 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0227474 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0226534 |
| ENOSF1 | enolase superfamily member 1 | -0.0226329 |
| RAB1A | RAB1A, member RAS oncogene family | -0.022418 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0223857 |
| NEK10 | NIMA-related kinase 10 | -0.0220584 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0220144 |
| RPS17 | ribosomal protein S17 | -0.0218721 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0217307 |
